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Table 3 Characteristics of the recipients and intra-operative period depending on donors BMI, univariate analysis

From: Impact of recipient and donor pretransplantation body mass index on early postosperative complications after lung transplantation

 

Overall,

N = 279 (100%)

Donor underweight,

N = 10 (3.6%)

Donor normal weight,

N = 128 (46%)

Donor overweight,

N = 95 (34%)

Donor obesity,

N = 46 (16%)

p-value

Before surgery

 Age, recipient, n (%)

57 [51–62]

56 [45–59]

57 [50–62]

57 [51–62]

58 [53–63]

0.46

 Male gender, recipient, n (%)

179 (64)

5 (50)

83 (65)

62 (65)

29 (63)

0.81

 Height, cm, med [IQR]

170 [163–176]

166 [159–175]

171 [164–176]

170 [163–177]

170 [164–177]

0.81

 Weight, Kg, med IQR]

69 [58- 80]

57 [46–78]

71 [59–82]

67 [57–79]

70 [60–80]

0.27

 BMI, Kg/m2, med[IQR]

24 [21–27]

21 [18–24]

24 [21–27]

23.9 [19–27]

24 [22–28]

0.19

 Diabetes mellitus, n (%)

30 (11)

3 (30)

15 (12)

10 (11)

2 (4)

0.12

 High blood pressure, n (%)

70 (25)

5 (50)

29 (23)

23 (24)

13 (28)

0.27

 Dyslipidemia, n (%)

57 (20)

3 (30)

27 (21)

19 (20)

8 (17)

0.79

 Ischc cardiopathy

27 (10)

1 (10)

11 (9)

10 (11)

5 (11)

0.91

Underlying disease

 COPD, n (%)

86 (31)

1 (10)

37 (29)

34 (36)

14 (30)

0.37

 PF, n (%)

130 (47)

7 (70)

65 (51)

35 (37)

23 (50)

0.071

 Other, n (%)

55 (20)

2 (20)

21 (16)

22 (23)

10 (22)

0.59

 High flow oxygenotherapy before surgery, n (%)

46 (16)

3 (30)

22 (17)

15 (16)

6 (13)

0.59

 MV before surgery, n (%)

4 (1.4)

0 (0)

1 (1)

3 (3.2)

0 (0)

0.47

 ECMO support before surgery, n (%)

21 (8)

2 (20)

8 (6)

8 (8)

3 (7)

0.38

 Tobacco use, n (%)

190 (68)

5 (50)

84 (66)

70 (74)

31 (67)

0.34

 Peripheral arterial disease, n (%)

12 (4)

0 (0)

7 (6)

5 (5)

0 (0)

0.41

 Pulmonary arterial hypertension, n (%)

134 (49)

5 (50)

63 (50)

44 (47)

22 (49)

0.97

 Dilatation of the right ventricle, n (ù°

77 (28)

3 (30)

32 (25)

32 (34)

10 (22)

0.36

 Ejection fraction of the left ventricle, %, med [IQR]

62 [58–68]

60 [58–64]

63 [58–69]

61 [60–65]

63 [55–68]

0.15

 Serum creatinine, med [IQR]

69 [56–80]

57 [54–76]

72 [56–84]

65 [53–78]

71 [59–83]

0.083

 High emergency LT, n (%)

53 (19)

3 (30)

23 (18)

19 (20)

8 (17)

0.74

 Retransplantation

7 (2.5)

1 (10)

4 (3)

0 (0)

2 (4.3)

0.067

 Redux

27 (9.9)

2 (22)

16 (13)

4 (4.3)

5 (11)

0.066

During surgery

 Bilateral LT, n (%)

193 (69)

6 (60)

88 (69)

70 (74)

29 (63)

0.52

 Duration of cold ischemia, min, first lung, med [IQR]

277 [240–334]

355 [285–420]

280 [240–342]

270 [226–330]

278 [240–340]

0.25

 Duration of cold ischemia, min, second lung, med [IQR]

375 [308–427]

428 [332–434]

390 [315–448]

360 [300–408]

365 [300–420]

0.20

 Duration of anesthesia, min, med [IQR]

420 [360–500]

390 [360–420]

420 [370–500]

420 [360–500]

410 [353–498]

0.66

Peridural anesthesia, n (%)

185 (67)

4 (40)

86 (68)

62 (67)

33 (73)

0.26

 ECMO support during surgery, n '(%)

202 (72)

7 (70)

96 (75)

62 (65)

37 (80)

0.23

 Catecholamine support during surgery, n (%)

273 (98)

10 (100)

126 (98)

92 (97)

45 (98)

0.89

 RBC transfusion during surgery, n (%)

188 (68)

9 (90)

85 (67)

66 (69)

28 (62)

0.40

 0 RBC unit, n (%)

88 (32)

1 (10)

42 (33)

29 (31)

16 (36)

 

 1–4 RBC units, n (%)

137 (49)

7 (70)

64 (50)

45 (47)

21 (47)

 

  ≥ 5 RBC units, n (%)

52 (19)

2 (20)

21 (17)

21 (22)

8 (18)

 

 Fresh frozen plasma transfusion, n (%)

175 (63)

6 (60)

79 (62)

61 (64)

29 (63)

0.98

 Platelet transfusion n (%)

56 (20)

5 (50)

24 (19)

16 (17)

11 (24)

0.094

 Vascular filling > 2500 mL, n (%)

236 (85)

10 (100)

104 (83)

84 (88)

38 (83)

0.37

  1. Quantitative variables were compared using Mann-Withney U test; qualitative datas using Chi-2 tests
  2. BMI body mass index, IQR interquartile range, ECMO extra-corporeal membrane oxygenation, LT lung transplantation, MV mechanichal ventilation, RBC red blood cell, FFP fresh frozen plasma