Skip to main content

Table 5 Postoperative complications during hospitalization in the ICU and short-term outcomes of the recipients; donor BMI univariate analysis

From: Impact of recipient and donor pretransplantation body mass index on early postosperative complications after lung transplantation

 

Overall,

N = 279 (100%)

Donor underweight,

N = 10 (3.6%)

Donor normal weight,

N = 128 (46%)

Donor overweight,

N = 95 (34%)

Donor obesity,

N = 46 (16%)

p value

At admission in the ICU

 SAPS II at admission in ICU, med [IQR]

44 [39–53]

40 [36–48]

45 [39–53]

44 [39–53]

45 [41–52]

0.41

 SOFA score at admission in ICU, med [IQR]

8 [7–10]

6 [6–9.3]

8 [7–10]

8 [7–10]

7.5 [6–10]

0.30

 Serum lactate > 3 mmol/L

101 (36)

3 (30)

46 (36)

35 (37)

17 (37)

0.99

 Serum lactate > 2 mmol/L

170 (61)

8 (80)

77 (60)

62 (65)

23 (50)

0.22

 Hemodynamic status during hospitalization in ICU

      

 Duration of catecholamine support, med [IQR]

2 [1–4]

2 [1–7]

2 [1–4]

2 [1–4]

2 [1–3]

0.75

 Atrial fibrillation, n (%)

103 (37)

7 (70)

39 (31)

43 (45)

14 (32)

0.020

 MOF syndrome, n (%)

94 (34)

4 (40)

42 (33)

36 (38)

12 (26)

0.54

 Duration of ECMO support

0 [0–2]

0 [0–0]

0 [0–2]

1 [0–3]

0 [0–0]

0.004

Respiratory complications

 Duration of MV, med [IQR]

3 [1–19]

5 [1–24]

3 [1–17]

3 [1–18]

3 [1–20]

0.98

 PGD, n (%)

147 (53)

4 (40)

66 (52)

55 (58)

22 (48)

0.54

 Grade 3 PGD, n (%)

74 (27)

2 (20)

36 (28)

30 (32)

6 (13)

0.10

 NBA administration, n (%)

85 (31)

4 (40)

36 (29)

32 (34)

13 (28)

0.73

 Duration of NBA administrationn, med [IQR]

3 [1–5]

5 [4–8]

3 [1–4]

3 [1–5]

2 [1–5]

0.45

 Prone positionning, n (%)

41 (15)

3 (30)

17 (13)

16 (17)

5 (11)

0.37

 Reintubation

50 (22)

2 (22)

26 (25)

11 (15)

11 (28)

0.28

 Tracheostomy for ventilation weaning, n (%)

80 (29)

3 (30)

38 (30)

27 (28)

12 (26)

0.97

Infectious complications

 Bacteriemia, n (%)

44 (16)

3 (30)

18 (14)

17 (18)

6 (13)

0.50

 Mediastinitis, n (%)

15 (5.4)

1 (10)

6 (4.7)

5 (5.3)

3 (6.5)

0.67

 Septic shock

83 (30)

2 (20)

36 (28)

32 (34)

13 (29)

0.76

 Number of pneumonia, med [IQR]

1 [1, 2]

1 [1–1.75]

1 [1, 2]

1 [1, 2]

1 [1, 2]

0.86

Surgical complications

 Surgical thoracic reintervention, n (%)

54 (19)

1 (10)

23 (18)

22 (23)

8 (17)

0.71

 Abdominal surgery, n (%)

29 (10)

2 (20)

13 (10)

11 (12)

3 (6.5)

0.50

Renal complications

 AKI, n (%)

133 (48)

4 (40)

62 (49)

43 (45)

24 (52)

0.84

 KDIGO stage, med [IQR]

1 [0–2]

0 [0–1]

1 [0–2]

1 [0–2]

1 [0–2]

0.50

 Renal replacement therapy, n(%)

44 (16)

0 (0)

19 (15)

19 (20)

6 (13)

0.39

Other complications

 Bronchial anastomotic dehiscence, n(%)

38 (16)

2 (25)

17 (15)

9 (11)

10 (24)

0.17

 Antibody mediated rejection, n (%)

75 (27)

2 (20)

36 (28)

27 (29)

10 (22)

0.83

 Acute cellular rejection, n (%)

33 (12)

1 (10)

17 (13)

10 (11)

5 (11)

0.94

Outcome

 Duration of ICU stay, med IQR]

17 [9–32]

20 [9, 11–32]

17 [10–35]

18 [12–28]

15 [9–31]

0.77

 Death on day-90, n (%)

49 (18)

0 (0)

21 (16)

20 (21)

8 (17)

0.45

  1. Quantitative variables were compared using Mann-Withney U test; qualitative datas using Chi-2 tests
  2. SAPS II simplified acute physiology score II, SOFA sequential organ failure assessment, ICU intensive care unit, ECMO extracorporeal membrane oxygenation, MOF multiorgan failure, PGD primary graft dysfunction, NBA neuroblocking agent, AKI acute kidney injury, RRT renal replacement therapy, KDIGO, kidney disease improving global outcome