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  1. Content type: Research article

    “Velcro-type” crackles on chest auscultation are considered a typical acoustic finding of Fibrotic Interstitial Lung Disease (FILD), however whether they may have a role in the early detection of these disorde...

    Authors: Giacomo Sgalla, Simon L. F. Walsh, Nicola Sverzellati, Sophie Fletcher, Stefania Cerri, Borislav Dimitrov, Dragana Nikolic, Anna Barney, Fabrizio Pancaldi, Luca Larcher, Fabrizio Luppi, Mark G. Jones, Donna Davies and Luca Richeldi

    Citation: BMC Pulmonary Medicine 2018 18:103

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  2. Content type: Research article

    The ability of circulating monocytes to develop into lung macrophages and promote lung tissue damage depends upon their phenotypic pattern of differentiation and activation. Whether this phenotypic pattern var...

    Authors: William D. Cornwell, Victor Kim, Xiaoxuan Fan, Marie Elena Vega, Frederick V. Ramsey, Gerard J. Criner and Thomas J. Rogers

    Citation: BMC Pulmonary Medicine 2018 18:101

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  3. Content type: Research article

    The chronic and progressive nature of chronic obstructive pulmonary disease (COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are increasingly being used for inhalation ther...

    Authors: Pablo Altman, Luis Wehbe, Juergen Dederichs, Tadhg Guerin, Brian Ament, Miguel Cardenas Moronta, Andrea Valeria Pino and Pankaj Goyal

    Citation: BMC Pulmonary Medicine 2018 18:100

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  4. Content type: Research article

    Regular airway clearance by chest physiotherapy and/or exercise is critical to lung health in cystic fibrosis (CF). Combination of cycling exercise and chest physiotherapy using the Flutter® device on sputum p...

    Authors: Thomas Radtke, Lukas Böni, Peter Bohnacker, Marion Maggi-Beba, Peter Fischer, Susi Kriemler, Christian Benden and Holger Dressel

    Citation: BMC Pulmonary Medicine 2018 18:99

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  5. Content type: Research article

    The purpose of the current study was to determine the association between sedentary time and physical activity with clinically relevant health outcomes among adults with impaired spirometry and those with or w...

    Authors: Shilpa Dogra, Joshua Good, Matthew P. Buman, Paul A. Gardiner, Jennifer L. Copeland and Michael K. Stickland

    Citation: BMC Pulmonary Medicine 2018 18:98

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  7. Content type: Research article

    Understanding the risk factors that are associated with the development of interstitial lung disease might have an important role in understanding the pathogenetic mechanism of interstitial lung disease as wel...

    Authors: Won-Il Choi, Sonila Dauti, Hyun Jung Kim, Sun Hyo Park, Jae Seok Park and Choong Won Lee

    Citation: BMC Pulmonary Medicine 2018 18:96

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  9. Content type: Research article

    Active pulmonary tuberculosis (TB) is associated with intra-hospital spread of the disease. Expeditious diagnosis and isolation are critical for infection control. However, factors that lead to delayed isolati...

    Authors: Sho Nishiguchi, Shusaku Tomiyama, Izumi Kitagawa and Yasuharu Tokuda

    Citation: BMC Pulmonary Medicine 2018 18:94

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  10. Content type: Research article

    Variation in hospital management of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may prolong length of stay, increasing the risk of hospital-acquired complications and wor...

    Authors: Sachin R. Pendharkar, Maria B. Ospina, Danielle A. Southern, Naushad Hirani, Jim Graham, Peter Faris, Mohit Bhutani, Richard Leigh, Christopher H. Mody and Michael K. Stickland

    Citation: BMC Pulmonary Medicine 2018 18:93

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  11. Content type: Case report

    Plague is a life-threatening disease caused by the bacterium, Yersinia pestis. Madagascar is the leading country for human plague cases worldwide. Human plague is a serious disease, particularly in its septicaemi...

    Authors: Voahangy Andrianaivoarimanana, Eric Bertherat, Rojo Rajaonarison, Tiana Rakotondramaro, Christophe Rogier and Minoarisoa Rajerison

    Citation: BMC Pulmonary Medicine 2018 18:92

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  12. Content type: Research article

    An increasing number of studies using primary human bronchial epithelial cells (BECs) have reported intrinsic differences in the expression of several genes between cells from asthmatic and non-asthmatic donor...

    Authors: Stephen R. Reeves, Kaitlyn A. Barrow, Maria P. White, Lucille M. Rich, Maryam Naushab and Jason S. Debley

    Citation: BMC Pulmonary Medicine 2018 18:91

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  13. Content type: Research article

    lipopolysaccharide-binding protein (LBP) has been to be a surrogate marker of inflammation in OSA. This study aimed to test the hypothesis that the concentration of LBP is elevated in adult patients with obstr...

    Authors: Yinfeng Kong, Zhijun Li, Tingyu Tang, Haiyan Wu, Juan Liu, Liang Gu, Tian Zhao and Qingdong Huang

    Citation: BMC Pulmonary Medicine 2018 18:90

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  14. Content type: Research article

    Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in br...

    Authors: Eric V. Neufeld, Brett A. Dolezal, William Speier and Christopher B. Cooper

    Citation: BMC Pulmonary Medicine 2018 18:89

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  15. Content type: Research article

    Mortality prediction of pneumonia by severity scores in patients with multiple underlying health conditions has not fully been investigated. This prospective cohort study is to identify mortality-associated un...

    Authors: Sugihiro Hamaguchi, Motoi Suzuki, Kota Sasaki, Masahiko Abe, Takao Wakabayashi, Eiichiro Sando, Makito Yaegashi, Shimpei Morimoto, Norichika Asoh, Naohisa Hamashige, Masahiro Aoshima, Koya Ariyoshi and Konosuke Morimoto

    Citation: BMC Pulmonary Medicine 2018 18:88

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  16. Content type: Research article

    Data on the lung microbiome in HIV-infected children is limited. The current study sought to determine the lung microbiome in HIV-associated bronchiectasis and to assess its association with pulmonary exacerba...

    Authors: Refiloe Masekela, Solize Vosloo, Stephanus N. Venter, Wilhelm Z. de Beer and Robin J. Green

    Citation: BMC Pulmonary Medicine 2018 18:87

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  17. Content type: Research article

    In people with cystic fibrosis infection with NonTuberculous Mycobacteria is of increasing prevalence. Mycobacterium abscessus complex is of particular concern and has been associated with adverse clinical outcom...

    Authors: Adrien Tissot, Matthew F. Thomas, Paul A. Corris and Malcolm Brodlie

    Citation: BMC Pulmonary Medicine 2018 18:86

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  18. Content type: Research article

    Non-tuberculous mycobacteria (NTM) infection is an increasing problem worldwide. The epidemiology of NTM in most Asian countries is unknown. This study investigated the epidemiology, and clinical profile of in...

    Authors: Albert Y. H. Lim, Sanjay H. Chotirmall, Eric T. K. Fok, Akash Verma, Partha P. De, Soon Keng Goh, Ser Hon Puah, Daryl E. L. Goh and John A. Abisheganaden

    Citation: BMC Pulmonary Medicine 2018 18:85

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  19. Content type: Research article

    Bronchiectasis is a chronic respiratory condition. Persistent bacterial colonisation in the stable state with increased and sometimes altered bacterial burden during exacerbations are accepted as key features ...

    Authors: Alicia B. Mitchell, Bassel Mourad, Lachlan Buddle, Matthew J. Peters, Brian G. G. Oliver and Lucy C. Morgan

    Citation: BMC Pulmonary Medicine 2018 18:84

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  20. Content type: Review

    Bronchiectasis is a disease associated with chronic progressive and irreversible dilatation of the bronchi and is characterised by chronic infection and associated inflammation. The prevalence of bronchiectasi...

    Authors: Ravishankar Chandrasekaran, Micheál Mac Aogáin, James D. Chalmers, Stuart J. Elborn and Sanjay H. Chotirmall

    Citation: BMC Pulmonary Medicine 2018 18:83

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  21. Content type: Research article

    Lung transplantation is a well-established treatment for end-stage non-cystic fibrosis bronchiectasis (BR), though information regarding outcomes of transplantation remains limited. Our results of lung transpl...

    Authors: Jodie Birch, Syba S. Sunny, Katy L. M. Hester, Gareth Parry, F. Kate Gould, John H. Dark, Stephen C. Clark, Gerard Meachery, James Lordan, Andrew J. Fisher, Paul A. Corris and Anthony De Soyza

    Citation: BMC Pulmonary Medicine 2018 18:82

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  22. Content type: Research article

    Bronchiectasis is a heterogeneous disease which affects quality of life. Measuring symptoms and quality of life has proved challenging and research is limited by extrapolation of questionnaires and treatments ...

    Authors: Emily K. Dudgeon, Megan Crichton and James D. Chalmers

    Citation: BMC Pulmonary Medicine 2018 18:81

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  23. Content type: Review

    Bronchiectasis is an incurable lung disease characterised by irreversible airway dilatation. It causes symptoms including chronic productive cough, dyspnoea, and recurrent respiratory infections often requirin...

    Authors: Katy L. M. Hester, Julia Newton, Tim Rapley and Anthony De Soyza

    Citation: BMC Pulmonary Medicine 2018 18:80

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  24. Content type: Review

    Bronchiectasis is a common feature of severe inherited and acquired pulmonary disease conditions. Among inherited diseases, cystic fibrosis (CF) is the major disorder associated with bronchiectasis, while acqu...

    Authors: Jürgen Schäfer, Matthias Griese, Ravishankar Chandrasekaran, Sanjay H. Chotirmall and Dominik Hartl

    Citation: BMC Pulmonary Medicine 2018 18:79

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  25. Content type: Research article

    Those affected by advanced fibrotic interstitial lung diseases have limited treatment options and in the terminal stages, the focus of care is on symptom management. However, quantitatively, little is known ab...

    Authors: Sabrina Carvajalino, Carla Reigada, Miriam J. Johnson, Mendwas Dzingina and Sabrina Bajwah

    Citation: BMC Pulmonary Medicine 2018 18:78

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  26. Content type: Case report

    Occupational lung diseases, such as pneumoconiosis, are one of the health problems of dental workers that have been receiving increasing interest. Pulmonary amyloidosis is a heterogenous group of diseases, and...

    Authors: Taizou Hirano, Tadahisa Numakura, Hiroshi Moriyama, Ryoko Saito, Yutaka Shishikura, Jun Shiihara, Hisatoshi Sugiura and Masakazu Ichinose

    Citation: BMC Pulmonary Medicine 2018 18:77

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  27. Content type: Editorial

    Bronchiectasis has an increasing profile within respiratory medicine. This chronic and irreversible airways disease is common but suffers from a lack of evidenced based therapy for patients and, a lack of unde...

    Authors: Sanjay H. Chotirmall and James D. Chalmers

    Citation: BMC Pulmonary Medicine 2018 18:76

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  28. Content type: Research article

    Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrosing interstitial pneumonia of unknown cause associated with the histopathologic and/or radiologic pattern of usual interstitial pneumonia (UI...

    Authors: Giulia Paolocci, Ilenia Folletti, Kjell Torén, Magnus Ekström, Marco Dell’Omo, Giacomo Muzi and Nicola Murgia

    Citation: BMC Pulmonary Medicine 2018 18:75

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  29. Content type: Research article

    Findings describing the relationship between pulmonary function and peripheral vascular function have been inconclusive. We explored this relationship in Guangzhou Biobank Cohort Study-Cardiovascular Subcohort...

    Authors: Jing Pan, Lin Xu, Tai Hing Lam, Chao Qiang Jiang, Wei Sen Zhang, Feng Zhu, Ya Li Jin, G. Neil Thomas, Kar Keung Cheng and Peymane Adab

    Citation: BMC Pulmonary Medicine 2018 18:74

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  30. Content type: Case report

    Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease (ILD) characterized by progressive fibrotic lesions of the visceral pleura and the sub-pleural parenchyma, affecting predominant...

    Authors: D. Hassoun, S. Dirou, P. P. Arrigoni, C. Durant, M. Hamidou, A. Néel and C. Agard

    Citation: BMC Pulmonary Medicine 2018 18:73

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  31. Content type: Research article

    There are currently no data on the prevalence of sleep-disordered breathing (SDB) in patients with newly-diagnosed lung cancer. This might be of interest given that SDB is associated with increased cancer inci...

    Authors: Michael Dreher, Stefan Krüger, Susanne Schulze-Olden, András Keszei, Jan Hendrik Storre, Holger Woehrle, Michael Arzt and Tobias Müller

    Citation: BMC Pulmonary Medicine 2018 18:72

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  32. Content type: Study protocol

    Pulmonary rehabilitation is an effective therapeutic intervention for people with chronic respiratory disease. However, fewer than 5% of eligible individuals receive pulmonary rehabilitation on an annual basis...

    Authors: Narelle S. Cox, Christine F. McDonald, Jennifer A. Alison, Ajay Mahal, Richard Wootton, Catherine J. Hill, Janet Bondarenko, Heather Macdonald, Paul O’Halloran, Paolo Zanaboni, Ken Clarke, Deidre Rennick, Kaye Borgelt, Angela T. Burge, Aroub Lahham, Bruna Wageck…

    Citation: BMC Pulmonary Medicine 2018 18:71

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  33. Content type: Review

    Interstitial lung diseases (ILDs) are a heterogeneous group of diseases characterized by widespread fibrotic and inflammatory abnormalities of the lung. Respiratory failure is a common complication in advanced...

    Authors: Paola Faverio, Federica De Giacomi, Luca Sardella, Giuseppe Fiorentino, Mauro Carone, Francesco Salerno, Jousel Ora, Paola Rogliani, Giulia Pellegrino, Giuseppe Francesco Sferrazza Papa, Francesco Bini, Bruno Dino Bodini, Grazia Messinesi, Alberto Pesci and Antonio Esquinas

    Citation: BMC Pulmonary Medicine 2018 18:70

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  34. Content type: Research article

    The most common cause of death of patients with idiopathic pulmonary fibrosis (IPF) has been reported to be the lung disease itself and mortality from IPF appears to be increasing. However, the causes of death...

    Authors: Miia Kärkkäinen, Hanna Nurmi, Hannu-Pekka Kettunen, Tuomas Selander, Minna Purokivi and Riitta Kaarteenaho

    Citation: BMC Pulmonary Medicine 2018 18:69

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  35. Content type: Research article

    Asthma is a common chronic respiratory disease leading to morbidity, mortality and impaired quality of life worldwide. Information on asthma prevalence in the Middle East is fragmented and relatively out-dated...

    Authors: Hesham Tarraf, Omur Aydin, Dilsad Mungan, Mohammad Albader, Bassam Mahboub, Adam Doble, Aaicha Lahlou, Luqman Tariq, Fayaz Aziz and Abdelkader El Hasnaoui

    Citation: BMC Pulmonary Medicine 2018 18:68

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  36. Content type: Research article

    The inherent risk of developing tuberculosis (TB) in HIV- infected individuals is further enhanced by hypovitaminosis D. Interventions that offset HIV-associated immune deterioration potentially arrest disease...

    Authors: Cuthbert Musarurwa, Lynn Sodai Zijenah, Doreen Zvipo Mhandire, Tsitsi Bandason, Kudakwashe Mhandire, Maria Mary Chipiti, Marshall Wesley Munjoma and Witmore Bayayi Mujaji

    Citation: BMC Pulmonary Medicine 2018 18:67

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  37. Content type: Research article

    Tuberculosis (TB) has been a major health problem globally since ages, and even today, it is a major cause of morbidity in millions of people each year. In 2015 alone, TB accounted for about 1.4 million deaths...

    Authors: S. K. Singh, Gyan Chandra Kashyap and Parul Puri

    Citation: BMC Pulmonary Medicine 2018 18:66

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  38. Content type: Research article

    Neutrophil-to-lymphocyte ratio (NLR) is a biomarker of inflammation in chronic obstructive pulmonary disease (COPD) patients. But, a meaningful threshold and the longitudinal changes are unknown. We aimed to i...

    Authors: Kaori Sakurai, Shotaro Chubachi, Hidehiro Irie, Akihiro Tsutsumi, Naofumi Kameyama, Takashi Kamatani, Hidefumi Koh, Takeshi Terashima, Hidetoshi Nakamura, Koichiro Asano and Tomoko Betsuyaku

    Citation: BMC Pulmonary Medicine 2018 18:65

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  39. Content type: Research article

    Despite reported long delays to initiate anti-TB treatment and poor outcomes in different parts of Ethiopia and elsewhere, evidences on association between the delay and treatment outcomes are scanty.

    Authors: Abyot Asres, Degu Jerene and Wakgari Deressa

    Citation: BMC Pulmonary Medicine 2018 18:64

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  40. Content type: Research article

    Pirfenidone, a pleiotropic anti-fibrotic treatment, has been shown to slow down disease progression of idiopathic pulmonary fibrosis (IPF), a fatal and devastating lung disease. Rapamycin, an inhibitor of fibr...

    Authors: M. Molina-Molina, C. Machahua-Huamani, V. Vicens-Zygmunt, R. Llatjós, I. Escobar, E. Sala-Llinas, P. Luburich-Hernaiz, J. Dorca and A. Montes-Worboys

    Citation: BMC Pulmonary Medicine 2018 18:63

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  41. Content type: Research article

    Pleural effusion (PE) drainage can relieve the symptoms of dyspnea; however, details of the resulting hemodynamic changes remain undefined.

    Authors: Zheng Wang, Qi-Zhe Cai, Cheng-Jun Ban, Duo Chen, Li-Li Xu, Xiao-Juan Wang, Zhen Wang, Yuan Yang, Xiu-Zhang Lv and Huan-Zhong Shi

    Citation: BMC Pulmonary Medicine 2018 18:62

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  42. Content type: Research article

    The purpose of the study is to describe the profile of patients with asthma and to identify the signifiant risks and the protective factors associated with asthma control.

    Authors: Imane Ghanname, Ahmed Chaker, Abha Cherkani Hassani, Laila Herrak, Serge Arnaul Ebongue, Mustapha Laine, Khalid Rahhali, Abdelhak Zoglat, Aida Maria Benitez Rexach, Samir Ahid and Yahia Cherrah

    Citation: BMC Pulmonary Medicine 2018 18:61

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  44. Content type: Case report

    Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific an...

    Authors: Safi Alqatari, Peter Riddell, Sinead Harney, Michael Henry and Grainne Murphy

    Citation: BMC Pulmonary Medicine 2018 18:59

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  45. Content type: Research article

    Although pre-puberty asthma is more prevalent in males, after puberty through middle-age, asthma is more prevalent in females. The surge of sex hormones with puberty might explain this gender switch.

    Authors: Mark D. DeBoer, Brenda R. Phillips, David T. Mauger, Joe Zein, Serpil C. Erzurum, Anne M. Fitzpatrick, Benjamin M. Gaston, Ross Myers, Kristie R. Ross, James Chmiel, Min Jie Lee, John V. Fahy, Michael Peters, Ngoc P. Ly, Sally E. Wenzel, Merritt L. Fajt…

    Citation: BMC Pulmonary Medicine 2018 18:58

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  46. Content type: Research article

    To compare, in terms of patient-ventilator interaction and performance, a new nasal mask (Respireo, AirLiquide, FR) with the Endotracheal tube (ET) and a commonly used nasal mask (FPM, Fisher and Paykel, NZ) f...

    Authors: Giorgio Conti, Giorgia Spinazzola, Cesare Gregoretti, Giuliano Ferrone, Andrea Cortegiani, Olimpia Festa, Marco Piastra, Luca Tortorolo and Roberta Costa

    Citation: BMC Pulmonary Medicine 2018 18:57

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  47. Content type: Research article

    Malignant pleural mesothelioma (MPM) is marked by its difficult diagnosis and poor prognosis. Medical thoracoscopy (MT) is an effective and safe procedure for the diagnosis of exudative pleural effusions and m...

    Authors: Li-Li Xu, Yuan Yang, Zhen Wang, Xiao-Juan Wang, Zhao-Hui Tong and Huan-Zhong Shi

    Citation: BMC Pulmonary Medicine 2018 18:56

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  48. Content type: Research article

    Recently awareness of the importance of Aspergillus colonization in the airway of patients with chronic obstructive pulmonary disease (COPD) was rising. The aim of this study was to investigate the clinical fe...

    Authors: Xunliang Tong, Anqi Cheng, Hongtao Xu, Jin Jin, Yimeng Yang, Sainan Zhu and Yanming Li

    Citation: BMC Pulmonary Medicine 2018 18:55

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  49. Content type: Research article

    Circulating adiponectin (ADPN) levels are inversely associated with disease severity in patients with chronic obstructive pulmonary disease (COPD), while studies assessing the relationship between ADPN and lun...

    Authors: Nina F. Caspersen, Helge Røsjø, Allan Flyvbjerg, Mette Bjerre, Anna Randby, Harald Hrubos-Strøm, Torbjørn Omland and Gunnar Einvik

    Citation: BMC Pulmonary Medicine 2018 18:54

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  50. Content type: Case report

    Allergic bronchopulmonary aspergillosis (ABPA) is an allergic pulmonary disease comprising a complex hypersensitivity reaction to Aspergillus fumigatus. Clinical features of ABPA are wheezing, mucoid impaction, a...

    Authors: Takeshi Terashima, Taro Shinozaki, Eri Iwami, Takahiro Nakajima and Tatsu Matsuzaki

    Citation: BMC Pulmonary Medicine 2018 18:53

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