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  1. Chronic obstructive pulmonary disease (COPD) is the fifth leading cause of death in China with a reported prevalence of 8.2% people aged ≥40 years. It is recommended that Chinese physicians follow Global Initi...

    Authors: Ting Yang, Baiqiang Cai, Bin Cao, Jian Kang, Fuqiang Wen, Wanzhen Yao, Jinping Zheng, Xia Ling, Hongyan Shang and Chen Wang

    Citation: BMC Pulmonary Medicine 2020 20:11

    Content type: Study protocol

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  2. Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was t...

    Authors: Johanna Pakkasela, Pinja Ilmarinen, Jasmin Honkamäki, Leena E. Tuomisto, Heidi Andersén, Päivi Piirilä, Hanna Hisinger-Mölkänen, Anssi Sovijärvi, Helena Backman, Bo Lundbäck, Eva Rönmark, Hannu Kankaanranta and Lauri Lehtimäki

    Citation: BMC Pulmonary Medicine 2020 20:9

    Content type: Research article

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  3. Scleromyxedema is a progressive, systemic connective tissue disorder characterized by fibro-mucous skin lesions and increased serum monoclonal immunoglobulin levels. Pulmonary involvement occurs in a subset of...

    Authors: Mazen Kreidy, Ali Al-Hilli, Ralph Yachoui and Jeffrey Resnick

    Citation: BMC Pulmonary Medicine 2020 20:8

    Content type: Case report

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  4. Pulse oximetry is widely used in the clinical setting. The purpose of this validation study was to investigate the level of agreement between oxygen saturations measured by pulse oximeter (SpO2) and arterial bloo...

    Authors: Janine Pilcher, Laura Ploen, Steve McKinstry, George Bardsley, Jimmy Chien, Lesley Howard, Sharon Lee, Lutz Beckert, Maureen Swanney, Mark Weatherall and Richard Beasley

    Citation: BMC Pulmonary Medicine 2020 20:7

    Content type: Research article

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  5. The purpose of this study was to evaluate the value of serum krebs von den lungen-6 (KL-6) level as a diagnostic indicator for connective tissue disease associated with interstitial lung disease (CTD-ILD).

    Authors: Hua Ma, Junhui Lu, Yuanyuan Song, Huixuan Wang and Songlou Yin

    Citation: BMC Pulmonary Medicine 2020 20:6

    Content type: Research article

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  6. Simultaneous infection in tuberculosis (TB) is rare. The mixed infection between Streptococcus anginosus group (SAG) and M. tuberculosis (MTB) has not been reported in children. The aim of this report was to desc...

    Authors: Napoleon González Saldaña, José Iván Castillo Bejarano, Marte Hernández Porras, Eduardo Arias de la Garza, Sofia Fortes Gutiérrez, Jose Luis Copado Gutiérrez and Hugo Juarez Olguin

    Citation: BMC Pulmonary Medicine 2020 20:5

    Content type: Case report

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  7. Marfan Syndrome (MFS) is a heritable connective tissue disorder with a high degree of clinical variability including respiratory diseases; a rare case of MFS with massive intrathoracic bleeding has been report...

    Authors: Yuki Yabuuchi, Hitomi Goto, Mizu Nonaka, Hiroaki Tachi, Tatsuya Akiyama, Naoki Arai, Hiroaki Ishikawa, Kentaro Hyodo, Kenji Nemoto, Yukiko Miura, Isano Hase, Shingo Usui, Shuji Oh-ishi, Kenji Hayashihara, Takefumi Saito and Tatsuya Chonan

    Citation: BMC Pulmonary Medicine 2020 20:4

    Content type: Case report

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  8. The two 52-week INPULSIS trials investigated nintedanib versus placebo in patients with IPF, FVC ≥50% predicted and DLco 30–79% predicted. The 24-week INSTAGE trial investigated nintedanib plus sildenafil vers...

    Authors: Luca Richeldi, Martin Kolb, Stéphane Jouneau, Wim A. Wuyts, Birgit Schinzel, Susanne Stowasser, Manuel Quaresma and Ganesh Raghu

    Citation: BMC Pulmonary Medicine 2020 20:3

    Content type: Research article

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  9. Gastroesophageal reflux disease (GERD) was suggested to be associated with exacerbations of chronic obstructive pulmonary disease (COPD) in recent years. The aim of this study was to examine the association be...

    Authors: Chunrong Huang, Yahui Liu and Guochao Shi

    Citation: BMC Pulmonary Medicine 2020 20:2

    Content type: Research article

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  10. Peripheral muscle weakness can be caused by both peripheral muscle and neural alterations. Although peripheral alterations cannot totally explain peripheral muscle weakness in COPD, the existence of an activat...

    Authors: Francois Alexandre, Nelly Héraud, Emilie Tremey, Nicolas Oliver, Dominique Bourgouin and Alain Varray

    Citation: BMC Pulmonary Medicine 2020 20:1

    Content type: Research article

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  11. Multiple studies have shown that diaphragmatic ultrasound can better predict the outcome of weaning in adults. However, there are few studies focusing on children, leading to a lack of sufficient clinical evid...

    Authors: Yang Xue, Zhen Zhang, Chu-Qiao Sheng, Yu-Mei Li and Fei-Yong Jia

    Citation: BMC Pulmonary Medicine 2019 19:270

    Content type: Research article

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  12. Skeletal muscle function dysfunction has been reported in patients with cystic fibrosis (CF). Studies so far showed inconclusive data whether reduced exercise capacity is related to intrinsic muscle dysfunctio...

    Authors: Katharina Ruf, Meinrad Beer, Herbert Köstler, Andreas Max Weng, Henning Neubauer, Alexander Klein, Kathleen Platek, Kristina Roth, Ralph Beneke and Helge Hebestreit

    Citation: BMC Pulmonary Medicine 2019 19:269

    Content type: Research article

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  13. This study aimed to determine the association between chronic periodontitis (CP) and community-acquired pneumonia (CAP) according to CP severity in the Korean population based on the National Health Insurance ...

    Authors: Seon-Jip Kim, Kyuwoong Kim, Seulggie Choi, Jooyoung Chang, Sung Min Kim, Sang Min Park and Hyun-Jae Cho

    Citation: BMC Pulmonary Medicine 2019 19:268

    Content type: Research article

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  14. The initial management of pneumothorax remains controversial, and we speculated that this might be because there is no method available for evaluation of air leak during initial management. We have developed a...

    Authors: Hiroyuki Kaneda, Takahito Nakano and Tomohiro Murakawa

    Citation: BMC Pulmonary Medicine 2019 19:267

    Content type: Technical advance

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  15. Workers in the zinc production and processing of galvanized sheet steel are exposed to a complex mixture of particles and gases, including zinc oxide (ZnO) that can affect human health. We aimed to study the e...

    Authors: Christian Monsé, Monika Raulf, Olaf Hagemeyer, Vera van Kampen, Benjamin Kendzia, Vitali Gering, Eike-Maximilian Marek, Birger Jettkant, Jürgen Bünger, Rolf Merget and Thomas Brüning

    Citation: BMC Pulmonary Medicine 2019 19:266

    Content type: Research article

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  16. Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is life-threatening. Several serum biomarkers, such as Krebs von den Lungen-6 (KL-6) and surfactant protein D (SP-D), are clinically used for evalua...

    Authors: Tetsuya Hanaka, Takashi Kido, Shingo Noguchi, Sohsuke Yamada, Hirotsugu Noguchi, Xin Guo, Aya Nawata, Ke-Yong Wang, Keishi Oda, Tsutomu Takaki, Hiroto Izumi, Hiroshi Ishimoto, Kazuhiro Yatera and Hiroshi Mukae

    Citation: BMC Pulmonary Medicine 2019 19:265

    Content type: Research article

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  17. The dose-response relationship of inhaled corticosteroid (ICS)/fast-onset long acting beta agonist (LABA) reliever therapy has not been formally addressed. The objective of this retrospective analysis is to as...

    Authors: Richard Beasley, James Harper, Grace Bird, Harriette Dunphy, Alex Semprini, Ian D. Pavord, Alberto Papi and Mark Weatherall

    Citation: BMC Pulmonary Medicine 2019 19:264

    Content type: Research article

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  18. The diagnosis of acute pulmonary embolism (PE) is one of the most challenging in emergency settings where prompt and accurate decisions need to be taken for life-saving purposes. Here, the assessment of the cl...

    Authors: Agnès Esiéné, Joel Noutakdie Tochie, Junette Arlette Mbengono Metogo, Paul Owono Etoundi and Jacqueline Ze Minkande

    Citation: BMC Pulmonary Medicine 2019 19:263

    Content type: Research article

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  19. Our study aimed to verify the prognostic value of circulating tumor cells (CTCs) prior to initial treatment on survival of non-small cell lung cancer (NSCLC) by using meta-analysis and system review of publish...

    Authors: Sha-Sha Jiang, Bo Deng, Yong-Geng Feng, Kai Qian, Qun-You Tan and Ru-Wen Wang

    Citation: BMC Pulmonary Medicine 2019 19:262

    Content type: Research article

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  20. Use of humidifier disinfectants (HD) at home leads to chemical airborne exposure, causing HD associated lung injury (HDLI) with high mortality. However, the lung function in children diagnosed with HDLI is not...

    Authors: Hyun-Ju Cho, So Yeon Lee, Donguk Park, Seung-Hun Ryu, Jisun Yoon, Sungsu Jung, Eun Lee, Song-I Yang and Soo-Jong Hong

    Citation: BMC Pulmonary Medicine 2019 19:261

    Content type: Research article

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  21. The emergence of multi-drug resistant pathogens is an urgent health-related problem, and the appropriate use of antibiotics is imperative. It is often difficult to identify the causative bacteria in patients w...

    Authors: Ken Otsuji, Kazumasa Fukuda, Midori Ogawa, Yoshihisa Fujino, Masayuki Kamochi and Mitsumasa Saito

    Citation: BMC Pulmonary Medicine 2019 19:260

    Content type: Research article

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  22. To promote the utilization of pulmonary function tests (PFT) through analyzing the data of PFT during the past seven years in one large teaching hospital in China.

    Authors: Fei Li, Zhi-wen Huang, Xiao-fei Wang, Hui-wen Xu, Hua Yu, Yan-bin Chen, Jian-an Huang, Jia-jia Wang and Wei Lei

    Citation: BMC Pulmonary Medicine 2019 19:259

    Content type: Research article

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  23. There is little information about vitamin D (Vit D) deficiency in patients with pulmonary hypertension (PH). The objective of this study was: 1) compare Vit D levels between patients with PH, left ventricular ...

    Authors: Andrés N. Atamañuk, Diego F. Litewka, Sergio J. Baratta, Ignacio M. Seropian, Graciela Perez Prados, Miguel O. Payaslian, Juan P. Ortiz Fragola and Pilar Escribano Subias

    Citation: BMC Pulmonary Medicine 2019 19:258

    Content type: Research article

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  24. Pulmonary veno-occlusive disease (PVOD) is a rare condition with poor prognosis, and lung transplantation is recommended as the only curative therapy. The role of pulmonary arterial hypertension targeted thera...

    Authors: Qin Luo, Qi Jin, Zhihui Zhao, Qing Zhao, Xue Yu, Lu Yan, Yi Zhang, Changming Xiong and Zhihong Liu

    Citation: BMC Pulmonary Medicine 2019 19:257

    Content type: Research article

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  25. Although the impact of asthma education on important outcomes (e.g. emergency visits) has been well established, only an estimated quarter of asthma patients in Germany have received patient education yet. The...

    Authors: Oxana Atmann, Klaus Linde, Christoph Werner, Ulrike Dorn and Antonius Schneider

    Citation: BMC Pulmonary Medicine 2019 19:256

    Content type: Research article

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  26. Health-related quality of life (HRQL) is impaired in patients with idiopathic pulmonary fibrosis (IPF). The King’s Brief Interstitial Lung Disease questionnaire (K-BILD) is a validated measure of HRQL, but no ...

    Authors: Thomas Skovhus Prior, Ole Hilberg, Saher Burhan Shaker, Jesper Rømhild Davidsen, Nils Hoyer, Surinder S. Birring and Elisabeth Bendstrup

    Citation: BMC Pulmonary Medicine 2019 19:255

    Content type: Research article

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  27. Pneumonia is an important cause of morbidity and mortality. COPD patients using inhaled corticosteroids (ICS) have an increased risk of pneumonia, but less is known about whether ICS treatment in asthma also i...

    Authors: Emil Ekbom, Jennifer Quint, Linus Schöler, Andrei Malinovschi, Karl Franklin, Mathias Holm, Kjell Torén, Eva Lindberg, Deborah Jarvis and Christer Janson

    Citation: BMC Pulmonary Medicine 2019 19:254

    Content type: Research article

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  28. Regular participation in physical activity by people with cystic fibrosis (CF) promotes positive clinical and health outcomes including reduced rate of decline in lung function, fewer hospitalizations and grea...

    Authors: Narelle S. Cox, Beverley Eldridge, Sarah Rawlings, Julianna Dreger, Jennifer Corda, Jennifer Hauser, Brenda M. Button, Jennifer Bishop, Amanda Nichols, Anna Middleton, Nathan Ward, Tiffany Dwyer, Owen W. Tomlinson, Sarah Denford, Alan R. Barker, Craig A. Williams…

    Citation: BMC Pulmonary Medicine 2019 19:253

    Content type: Study protocol

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  29. Mycoplasma pneumoniae is one of the most common pathogens causing community acquired pneumonia in children. Although the rate of macrolide-refractory Mycoplasma pneumoniae (MRMP) has increased, systemic glucocort...

    Authors: Hwan Soo Kim, In Suk Sol, Donghe Li, Miyoung Choi, Yun Jung Choi, Kyung Suk Lee, Ju Hee Seo, Yong Ju Lee, Hyeon-Jong Yang and Hyun Hee Kim

    Citation: BMC Pulmonary Medicine 2019 19:251

    Content type: Research article

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  30. The impact of anemia and red blood cell (RBC) transfusion on weaning from mechanical ventilation is not known. In theory, transfusions could facilitate liberation from the ventilator by improving oxygen transp...

    Authors: Alessandro Ghiani, Alexandros Sainis, Georgios Sainis and Claus Neurohr

    Citation: BMC Pulmonary Medicine 2019 19:250

    Content type: Research article

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  31. The diagnostic criteria for asthma-chronic obstructive pulmonary disease overlap have not been unified. Different studies have used different criteria, and this has led to diagnostic inconsistencies.

    Authors: Wenjing Ye, Xiaoming Li, Wen Gu, Xuejun Guo, Fengfeng Han and Song Liu

    Citation: BMC Pulmonary Medicine 2019 19:249

    Content type: Research article

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  32. This study investigated the sex-specific incidence of asthma and the effects of modifiable risk factors, particularly obesity, on asthma incidence among middle-aged and older individuals in Korea.

    Authors: Susan Park, Sun-Young Jung and Jin-Won Kwon

    Citation: BMC Pulmonary Medicine 2019 19:248

    Content type: Research article

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  33. The intensity and frequency of cough remain unclear in interstitial lung disease (ILD). The aim of this study was to evaluate the intensity and frequency of cough in idiopathic interstitial pneumonias (IIPs), ...

    Authors: Ryuhei Sato, Tomohiro Handa, Hisako Matsumoto, Takeshi Kubo and Toyohiro Hirai

    Citation: BMC Pulmonary Medicine 2019 19:247

    Content type: Research article

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  34. Lung adenocarcinoma associated transcript 1 (LUADT1) has been reported as an oncogenic long non-coding RNA (lncRNA) in lung adenocarcinoma, while its roles in small cell lung cancer (SCLC) are unknown. Our RNA...

    Authors: Dingxue Wang, Wenyu Wu, Wenqi Huang, Jinghui Wang, Li Luo and Dongxin Tang

    Citation: BMC Pulmonary Medicine 2019 19:246

    Content type: Research article

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  35. Preterm newborns typically require supplemental oxygen but hyperoxic conditions also damage the premature lung. Oxygen-induced lung damages are mainly studied in newborn mouse models using oxygen concentration...

    Authors: Anke Kindermann, Leonore Binder, Jan Baier, Beate Gündel, Andreas Simm, Roland Haase and Babett Bartling

    Citation: BMC Pulmonary Medicine 2019 19:245

    Content type: Research article

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    The Correction to this article has been published in BMC Pulmonary Medicine 2020 20:17

  36. During cardiopulmonary exercise testing (CPET), Idiopathic Pulmonary Fibrosis (IPF) patients do not reach their direct maximum voluntary ventilation (MVV) and have deranged gas exchange. Their exercise limitat...

    Authors: Benjamin D. Fox, Yael Shostak, Barak Pertzov, Baruch Vainshelboim, Shimon Itzhakian, Irit Terner and Mordechai R. Kramer

    Citation: BMC Pulmonary Medicine 2019 19:244

    Content type: Research article

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  37. The Robotic Endoscopic System (Auris Health, Inc., Redwood City, CA) has the potential to overcome several limitations of contemporary guided-bronchoscopic technologies for the diagnosis of lung lesions. Our o...

    Authors: Udit Chaddha, Stephen P. Kovacs, Christopher Manley, D. Kyle Hogarth, Gustavo Cumbo-Nacheli, Sivasubramanium V. Bhavani, Rohit Kumar, Manisha Shende, John P. Egan III and Septimiu Murgu

    Citation: BMC Pulmonary Medicine 2019 19:243

    Content type: Research article

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  38. Rapid stratification and appropriate treatment on admission are critical to saving lives of patients with acute pulmonary embolism (PE). None of the clinical prediction tools perform well when applied to all p...

    Authors: Yan Wang, He Yang, Lisong Qiao, Zheng Tan, Jin Jin, Jingjing Yang, Li Zhang, Bao Min Fang and Xiaomao Xu

    Citation: BMC Pulmonary Medicine 2019 19:242

    Content type: Research article

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  39. There are limited data regarding the efficacy and safety of remifentanil sedation for diagnostic bronchoscopy. The aim of this study was to evaluate the clinical efficacy and safety of remifentanil by comparin...

    Authors: Hyun Lee, Yeong Hun Choe and Seungyong Park

    Citation: BMC Pulmonary Medicine 2019 19:240

    Content type: Research article

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  40. Bone mineral density (BMD) has been positively associated with lung function in patients diagnosed with respiratory diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis. However, t...

    Authors: Xiang Zeng, Dongling Liu, Xiangmei Zhao, Ling Chao, Yuchun Li, Huijun Li, Wen Li, Lihui Gui and Weidong Wu

    Citation: BMC Pulmonary Medicine 2019 19:239

    Content type: Research article

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  41. Pediatric community acquired pneumonia (pedCAP) is one of the leading causes for childhood morbidity accounting for up to 20% of pediatric hospital admissions in high income countries. In spite of its high mor...

    Authors: Martin Wetzke, Matthias Volkmar Kopp, Jürgen Seidenberg, Christian Vogelberg, Tobias Ankermann, Christine Happle, Gesche Voigt, Holger Köster, Thomas Illig, Christiane Lex, Antje Schuster, Marcus Panning, Grit Barten, Gernot Rohde, Tobias Welte and Gesine Hansen

    Citation: BMC Pulmonary Medicine 2019 19:238

    Content type: Study protocol

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  42. The use of extracorporeal membrane oxygenation (ECMO) in awake, spontaneously breathing and non-intubated patients (awake ECMO) may be a novel therapeutic strategy for severe acute respiratory distress syndrom...

    Authors: Jingen Xia, Sichao Gu, Min Li, Donglin Liu, Xu Huang, Li Yi, Lijuan Wu, Guohui Fan and Qingyuan Zhan

    Citation: BMC Pulmonary Medicine 2019 19:237

    Content type: Research article

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  43. Bronchoalveolar lavage is a useful bronchoscopy technique. However, studies in “normal” children populations are few. Furthermore, the anti-inflammatory effects of exogenous pulmonary surfactants on the bronch...

    Authors: Lyné van Rensburg, Johann M. van Zyl, Johan Smith and Pierre Goussard

    Citation: BMC Pulmonary Medicine 2019 19:236

    Content type: Research article

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  44. Following publication of the original article [1], the authors flagged that the article had been provided with the names of the authors (not including the STORICO study group) in the wrong order: the ‘Given Na...

    Authors: Nicola Scichilone, Raffaele Antonelli Incalzi, Francesco Blasi, Pietro Schino, Giuseppina Cuttitta, Alessandro Zullo, Alessandra Ori and Giorgio Walter Canonica

    Citation: BMC Pulmonary Medicine 2019 19:235

    Content type: Correction

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    The original article was published in BMC Pulmonary Medicine 2019 19:171

  45. Exogenous lipoid pneumonia is a rare disease resulting from intra-alveolar accumulation of lipids of mineral, vegetal, or animal origin, that induce a foreign body type of inflammatory reaction in the lungs. G...

    Authors: Jacques BOUTROS, Marine MUZZONE, Jonathan BENZAQUEN, Michael LEVRAUT, Charles-Hugo MARQUETTE, Fanny ROCHER, Yann DIASCORN, Bernard PADOVANI, Véronique HOFMAN and Sylvie LEROY

    Citation: BMC Pulmonary Medicine 2019 19:234

    Content type: Case report

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  46. While inhaled bronchodilators reduce symptoms and acute exacerbations of chronic obstructive pulmonary disease (COPD), their use is associated with increased cardiovascular events in some studies. This study i...

    Authors: Yen-Fu Chen, Yi-Ching Cheng, Chien-Hong Chou, Chung-Yu Chen and Chong-Jen Yu

    Citation: BMC Pulmonary Medicine 2019 19:233

    Content type: Research article

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  47. Recurrent pleural effusion is a common cause of dyspnoea, cough and chest pain during the course of malignant diseases. Chemical pleurodesis had been the only definitive treatment option until two decades ago....

    Authors: Nikolaj Frost, Martin Brünger, Christoph Ruwwe-Glösenkamp, Matthias Raspe, Antje Tessmer, Bettina Temmesfeld-Wollbrück, Dirk Schürmann, Norbert Suttorp and Martin Witzenrath

    Citation: BMC Pulmonary Medicine 2019 19:232

    Content type: Research article

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  48. Quantifying the effects of personal health behaviors and environmental exposure on asthma flare-ups is a challenge. Most studies have focused on monitoring the symptoms and drug usage for relieving symptoms. I...

    Authors: Ta-Chien Chan, Tsuey-Hwa Hu, Yen-Hua Chu and Jing-Shiang Hwang

    Citation: BMC Pulmonary Medicine 2019 19:231

    Content type: Research article

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