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  1. Previous health economic studies recommend either a dual screening strategy [tuberculin skin test (TST) followed by interferon-γ-release assay (IGRA)] or a single one [IGRA only] for latent tuberculosis infect...

    Authors: Anil Pooran, Helen Booth, Robert F Miller, Geoff Scott, Motasim Badri, Jim F Huggett, Graham Rook, Alimuddin Zumla and Keertan Dheda
    Citation: BMC Pulmonary Medicine 2010 10:7
  2. Preventing ventilator-associated lung injury (VALI) has become pivotal in mechanical ventilation of patients with acute lung injury (ALI) or its more severe form, acute respiratory distress syndrome (ARDS). In...

    Authors: Rogier M Determann, Annick ANM Royakkers, Jack J Haitsma, Haibo Zhang, Arthur S Slutsky, V Marco Ranieri and Marcus J Schultz
    Citation: BMC Pulmonary Medicine 2010 10:6
  3. Non-cystic fibrosis bronchiectasis is characterised by sputum production, exercise limitation and recurrent infections. Although pulmonary rehabilitation is advocated for this patient group, its effects are un...

    Authors: Annemarie L Lee, Nola Cecins, Catherine J Hill, Anne E Holland, Linda Rautela, Robert G Stirling, Phillip J Thompson, Christine F McDonald and Sue Jenkins
    Citation: BMC Pulmonary Medicine 2010 10:5
  4. Nitric oxide (NO) shows differing concentrations in lower and upper airways. Patients after total laryngectomy are the only individuals, in whom a complete separation of upper and lower airways is guaranteed. ...

    Authors: Matthias F Kramer, Bernhard Olzowy, Annette Bihler, Dorothea de la Motte, Dennis Nowak, Rudolf A Jörres and Holger Dressel
    Citation: BMC Pulmonary Medicine 2010 10:4
  5. IL-13 has been implicated in the development of airway inflammation and hyperresponsiveness. This study investigated the multiple-dose pharmacokinetics and safety profile of human anti-IL-13 antibody (CAT-354)...

    Authors: Dave Singh, Binita Kane, Nestor A Molfino, Raffaella Faggioni, Lorin Roskos and Ashley Woodcock
    Citation: BMC Pulmonary Medicine 2010 10:3
  6. Urinary incontinence (UI) is a distressing problem for older people. To investigate the relationship between UI and respiratory symptoms among middle-aged and older men, a community-based study was conducted i...

    Authors: Fumi Hirayama, Andy H Lee, Tetsuo Hiramatsu and Yoshimasa Tanikawa
    Citation: BMC Pulmonary Medicine 2010 10:2
  7. Poor adherence with prescribed asthma medication is a major barrier to positive treatment outcomes. This study was designed to determine the effect of a once-daily administration of mometasone furoate administ...

    Authors: David Price, Anne Robertson, Kevin Bullen, Cynthia Rand, Rob Horne and Heribert Staudinger
    Citation: BMC Pulmonary Medicine 2010 10:1
  8. Airway inflammation and airway hyperresponsiveness (AHR) are two characteristic features of asthma. Fractional exhaled nitric oxide (FENO) has shown good correlation with AHR in asthmatics. Less information is...

    Authors: Valérie Demange, Abraham Bohadana, Nicole Massin and Pascal Wild
    Citation: BMC Pulmonary Medicine 2009 9:53
  9. Early detection of exacerbations by COPD patients initiating prompt interventions has shown to be clinically relevant. Until now, research failed to identify the effectiveness of a written individualized Actio...

    Authors: Jaap CA Trappenburg, Lieselotte Koevoets, Gerdien H de Weert-van Oene, Evelyn M Monninkhof, Jean Bourbeau, Thierry Troosters, Theo JM Verheij, Jan-Willem J Lammers and Augustinus JP Schrijvers
    Citation: BMC Pulmonary Medicine 2009 9:52
  10. High levels of exhaled carbon monoxide (eCO) are a marker of airway or lung inflammation. We investigated whether hypo- or hyperventilation can affect measured values.

    Authors: Franco Cavaliere, Carmen Volpe, Riccardo Gargaruti, Andrea Poscia, Michele Di Donato, Giovanni Grieco and Umberto Moscato
    Citation: BMC Pulmonary Medicine 2009 9:51
  11. Spirometry is a cost-effective diagnostic tool for evaluation of lung function and for case-finding in a resource-limited setting. The acceptance of this test depends on the awareness of its indications and th...

    Authors: Olufemi O Desalu, Olusegun A Busari, Cajetan C Onyedum, Fatai K Salawu, Olusegun A Obateru, Kelechukwu C Nwogu and Alakija K Salami
    Citation: BMC Pulmonary Medicine 2009 9:50
  12. Despite consensus criteria, diagnosing acute lung injury, or its more severe form acute respiratory distress syndrome (ALI/ARDS) remains challenging. Adding objective measures, such as plasma levels of biologi...

    Authors: Rogier M Determann, Julian L Millo, Sam Waddy, Rene Lutter, Chris S Garrard and Marcus J Schultz
    Citation: BMC Pulmonary Medicine 2009 9:49
  13. The collection of exhaled breath condensate (EBC) is a suitable and non-invasive method for evaluation of airway inflammation. Several studies indicate that the composition of the condensate and the recovery o...

    Authors: Frank Hoffmeyer, Monika Raulf-Heimsoth, Volker Harth, Jürgen Bünger and Thomas Brüning
    Citation: BMC Pulmonary Medicine 2009 9:48
  14. Previous studies have shown conflicting results for the association between TLR4 polymorphism (Asp299Gly) and lung function. We investigated the influence of TLR4 Asp299Gly, a polymorphism, on lung function in...

    Authors: Punam Pahwa, Chandima P Karunanayake, Donna C Rennie, Yue Chen, David A Schwartz and James A Dosman
    Citation: BMC Pulmonary Medicine 2009 9:46
  15. To determine whether oral administration of geranylgeranylacetone (GGA), a nontoxic anti-ulcer drug that is an inducer of heat shock protein (HSP) 70, protects against drug-induced lung injury/fibrosis in vivo.

    Authors: Takayoshi Fujibayashi, Naozumi Hashimoto, Mayumi Jijiwa, Yoshinori Hasegawa, Toshihisa Kojima and Naoki Ishiguro
    Citation: BMC Pulmonary Medicine 2009 9:45
  16. Tigecycline, an expanded broad-spectrum glycylcycline, exhibits in vitro activity against many common pathogens associated with community-acquired pneumonia (CAP), as well as penetration into lung tissues that...

    Authors: Cristina Tanaseanu, Slobodan Milutinovic, Petre I Calistru, Janos Strausz, Marius Zolubas, Valeriy Chernyak, Nathalie Dartois, Nathalie Castaing, Hassan Gandjini and C Angel Cooper
    Citation: BMC Pulmonary Medicine 2009 9:44
  17. Asthma and COPD are major health problems and an extensive burden for the patient and the health care system. Patient education has been recommended, but the influence on knowledge and health outcomes is not f...

    Authors: Margareta Emtner, Anna Hedin, Mikael Andersson and Christer Janson
    Citation: BMC Pulmonary Medicine 2009 9:43
  18. Epidemiological research into the role of traffic pollution on chronic respiratory and allergic disease has focused primarily on children. Studies in adults, in particular those based on objective outcomes suc...

    Authors: Mar Pujades-Rodríguez, Tricia McKeever, Sarah Lewis, Duncan Whyatt, John Britton and Andrea Venn
    Citation: BMC Pulmonary Medicine 2009 9:42
  19. Lithuania is a country with a high incidence of tuberculosis (TB), despite a high coverage with bacille Calmette-Guerin (BCG) vaccination. Until now the only method used to detect latent TB infection was the t...

    Authors: Edita Hansted, Angele Andriuskeviciene, Raimundas Sakalauskas, Rimantas Kevalas and Brigita Sitkauskiene
    Citation: BMC Pulmonary Medicine 2009 9:41
  20. Solitary endobronchial papillomas (SEP) are rare tumors and most of them are described by case report. A misdiagnosis is common with viral related papillomas. A histopathological classification has recently pe...

    Authors: Fabrice Paganin, Martine Prevot, Jean Baptiste Noel, Marie Frejeville, Claude Arvin-Berod and Arnaud Bourdin
    Citation: BMC Pulmonary Medicine 2009 9:40
  21. The lung consists of at least seven compartments with relevance to immune reactions. Compartment 1 - the bronchoalveolar lavage (BAL), which represents the cells of the bronchoalveolar space: From a diagnostic...

    Authors: Thomas Tschernig and Reinhard Pabst
    Citation: BMC Pulmonary Medicine 2009 9:39
  22. Multicentre drug use evaluations are described in the literature infrequently and usually publish only the results. The purpose of this paper is to describe the experience of Queensland hospitals participating...

    Authors: Lisa K Pulver, Susan E Tett and Judith Coombes
    Citation: BMC Pulmonary Medicine 2009 9:38
  23. There is a substantial body of evidence on the efficacy of yoga in the management of bronchial asthma. Many studies have reported, as the effects of yoga on bronchial asthma, significant improvements in pulmon...

    Authors: Ramaprabhu Vempati, Ramesh Lal Bijlani and Kishore Kumar Deepak
    Citation: BMC Pulmonary Medicine 2009 9:37
  24. Heart surgery is associated with an occurrence of pulmonary complications. The aim of this study was to determine whether pre-surgery respiratory physiotherapy reduces the incidence of post-surgery pulmonary c...

    Authors: Isabel Yánez-Brage, Salvador Pita-Fernández, Alberto Juffé-Stein, Ursicino Martínez-González, Sonia Pértega-Díaz and Ángeles Mauleón-García
    Citation: BMC Pulmonary Medicine 2009 9:36
  25. Cardiac Troponin T (cTnT) elevation during exacerbations of chronic obstructive pulmonary disease (COPD) is associated with increased mortality the first year after hospital discharge. The factors associated w...

    Authors: Pål H Brekke, Torbjørn Omland, Stein Harald Holmedal, Pål Smith and Vidar Søyseth
    Citation: BMC Pulmonary Medicine 2009 9:35
  26. In asthma interleukin (IL)-13 is increased in the airway compared with non-asthmatic eosinophilic bronchitis. Whether this differential expression is specific to the airway or is more generalised is uncertain.

    Authors: Salman Siddiqui, Glenn Cruse, Susan Mckenna, William Monteiro, Vijay Mistry, Andrew Wardlaw and Christopher Brightling
    Citation: BMC Pulmonary Medicine 2009 9:34
  27. N-chlorotaurine, a long-lived oxidant produced by human leukocytes, can be applied in human medicine as an endogenous antiseptic. Its antimicrobial activity can be enhanced by ammonium chloride. This study was...

    Authors: Ralf Geiger, Benedikt Treml, Anna Pinna, Linn Barnickel, Harald Prossliner, Hannes Reinstadler, Michael Pilch, Maria Hauer, Christoph Walther, Hans-Jörg Steiner, Thomas Giese, Andreas Wemhöner, Sabine Scholl-Bürgi, Waldemar Gottardi, Roland Arnitz, Consolato Sergi…
    Citation: BMC Pulmonary Medicine 2009 9:33
  28. Statins have anti-inflammatory and immunomodulating properties which could possibly influence inflammatory airways disease. We assessed evidence for disease modifying effects of statin treatment in patients wi...

    Authors: Claudia C Dobler, Keith K Wong and Guy B Marks
    Citation: BMC Pulmonary Medicine 2009 9:32
  29. To evaluate the sensitivity, specificity and predictive values of spirometry for the diagnosis of chronic obstructive pulmonary disease (COPD) and asthma in patients suspected of suffering from an obstructive ...

    Authors: Antonius Schneider, Lena Gindner, Lisa Tilemann, Tjard Schermer, Geert-Jan Dinant, Franz Joachim Meyer and Joachim Szecsenyi
    Citation: BMC Pulmonary Medicine 2009 9:31
  30. Due to large-scale destruction, changes in membrane diffusion (Dm) may occur in cystic fibrosis (CF), in correspondence to alterations observed by computed tomography (CT). Dm can be easily quantified via the ...

    Authors: Holger Dressel, Laura Filser, Rainald Fischer, Katharina Marten, Ullrich Müller-Lisse, Dorothea de la Motte, Dennis Nowak, Rudolf M Huber and Rudolf A Jörres
    Citation: BMC Pulmonary Medicine 2009 9:30
  31. Exercise-related respiratory symptoms in the diagnosis of exercise-induced bronchoconstriction (EIB) have poor predictive value. The aim of this study was to evaluate how athletes presenting with these symptom...

    Authors: James H Hull, Peter J Hull, Jonathan P Parsons, John W Dickinson and Les Ansley
    Citation: BMC Pulmonary Medicine 2009 9:29
  32. Increased respiratory rate (tachypnea) is frequently observed as a clinical sign of influenza pneumonia in pediatric patients admitted to the hospital. We previously demonstrated that influenza infection of ad...

    Authors: Elman L Trias, Arash Hassantoufighi, Gregory A Prince and Maryna C Eichelberger
    Citation: BMC Pulmonary Medicine 2009 9:28
  33. SCF (stem cell factor) is a pleiotropic cytokine exerting its role at different stages of bone marrow development and affecting eosinophil activation, mast cells and basophil chemotaxis and survival. The aim o...

    Authors: Joanna S Makowska, Malgorzata Cieslak and Marek L Kowalski
    Citation: BMC Pulmonary Medicine 2009 9:27
  34. Pulmonary rehabilitation is known to be a beneficial treatment for COPD patients. To date, however, there is no agreement for how long a rehabilitation program should be implemented. In addition, current views...

    Authors: David Stav, Meir Raz and Isaac Shpirer
    Citation: BMC Pulmonary Medicine 2009 9:26
  35. Asthma is associated with enormous healthcare expenditures that include both direct and indirect costs. It is also associated with the loss of future potential earnings related to both morbidity and mortality....

    Authors: Katayoun Bahadori, Mary M Doyle-Waters, Carlo Marra, Larry Lynd, Kadria Alasaly, John Swiston and Js Mark FitzGerald
    Citation: BMC Pulmonary Medicine 2009 9:24
  36. Incense burning has been reported to adversely affect respiratory health. The aim of this study was to explore whether exposure to bakhour contributes to the prevalence of asthma and/or triggers its symptoms i...

    Authors: Omar A Al-Rawas, Abdullah A Al-Maniri and Bazdawi M Al-Riyami
    Citation: BMC Pulmonary Medicine 2009 9:23
  37. Herpes simplex virus type-1 (HSV-1) has been described to cause respiratory tract infections in critically ill patients or in individuals that are immunocompromised. It is a continuing matter of debate under w...

    Authors: Matthias N Witt, Gerald S Braun, Stephan Ihrler and Holger Schmid
    Citation: BMC Pulmonary Medicine 2009 9:22
  38. Interferon gamma release assays, including the QuantiFERON® TB Gold In Tube (QFT) have been shown to be accurate in diagnosing Mycobacterium tuberculosis infection. These assays however, do not discriminate betwe...

    Authors: Novel N Chegou, Gillian F Black, Martin Kidd, Paul D van Helden and Gerhard Walzl
    Citation: BMC Pulmonary Medicine 2009 9:21
  39. Recombinant human activated protein C (rhAPC) is associated with improved survival in high-risk patients with severe sepsis; however, the effects of both lipopolysaccharide (LPS) and rhAPC on the bronchoalveol...

    Authors: Russell P Bowler, Nichole Reisdorph, Richard Reisdorph and Edward Abraham
    Citation: BMC Pulmonary Medicine 2009 9:20
  40. While modulation of the serotonin transporter (5HTT) has shown to be a risk factor for pulmonary arterial hypertension for almost 40 years, there is a lack of in vivo data about the broad molecular effects of ...

    Authors: Daniel Crona, Julie Harral, Serge Adnot, Saadia Eddahibi and James West
    Citation: BMC Pulmonary Medicine 2009 9:19
  41. The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary hyper...

    Authors: Andriana I Papaioannou, Epaminondas Zakynthinos, Konstantinos Kostikas, Theodoros Kiropoulos, Angela Koutsokera, Athanasios Ziogas, Athanasios Koutroumpas, Lazaros Sakkas, Konstantinos I Gourgoulianis and Zoe D Daniil
    Citation: BMC Pulmonary Medicine 2009 9:18
  42. The incidence and morbidity of wheezing illnesses and childhood asthma is especially high in poor urban areas. This paper describes the study design, methods, and population of the Urban Environment and Childh...

    Authors: James E Gern, Cynthia M Visness, Peter J Gergen, Robert A Wood, Gordon R Bloomberg, George T O'Connor, Meyer Kattan, Hugh A Sampson, Frank R Witter, Megan T Sandel, Wayne G Shreffler, Rosalind J Wright, Samuel J Arbes Jr and William W Busse
    Citation: BMC Pulmonary Medicine 2009 9:17
  43. Sputum smear microscopy is the standard diagnostic method for detection of smear positive pulmonary tuberculosis (TB). Insufficient quality of sputum might result in missing cases. In this study we aimed at as...

    Authors: Mateus Sakundarno, Nurjazuli Nurjazuli, Sutopo Patria Jati, Retna Sariningdyah, Sumarsono Purwadi, Bachti Alisjahbana and Marieke J van der Werf
    Citation: BMC Pulmonary Medicine 2009 9:16
  44. Chronic Obstructive Pulmonary Disease (COPD) is a systemic disease; morbidity and mortality due to COPD are on the increase, and it has great impact on patients' lives. Most COPD patients are managed by genera...

    Authors: Lara Siebeling, Gerben ter Riet, Willem M van der Wal, Ronald B Geskus, Marco Zoller, Patrick Muggensturm, Irena Joleska and Milo A Puhan
    Citation: BMC Pulmonary Medicine 2009 9:15
  45. Drawing from previous studies, the traditional routine diagnostic microbiology evaluation of samples from chronic respiratory conditions may provide an incomplete picture of the bacteria present in airways dis...

    Authors: Geraint B Rogers, Thomas WV Daniels, Andrew Tuck, Mary P Carroll, Gary J Connett, Gondi JP David and Kenneth D Bruce
    Citation: BMC Pulmonary Medicine 2009 9:14
  46. Asthma is a difficult diagnosis to establish in preschool children. A few years ago, our group presented a prediction rule for young children at risk for asthma in general practice. Before this prediction rule...

    Authors: Karina E van Wonderen, Lonneke B van der Mark, Jacob Mohrs, Ronald B Geskus, Willem M van der Wal, Wim MC van Aalderen, Patrick JE Bindels and Gerben ter Riet
    Citation: BMC Pulmonary Medicine 2009 9:13
  47. Nonattendance for scheduled appointments disturbs the effective management of pediatric pulmonary clinics. We hypothesized that the reasons for non-attendance and the necessary solutions might be different in ...

    Authors: Aviv D Goldbart, Jacob Dreiher, Daniel A Vardy, Soliman Alkrinawi and Arnon D Cohen
    Citation: BMC Pulmonary Medicine 2009 9:12
  48. Recent studies have provided evidence for a link between leptin and tumor necrosis factor-alpha (TNF-α). Insulin-like growth factor I (IGF-I) mediates the metabolic effects of growth hormone (GH). The GH axis ...

    Authors: Prokopis Kythreotis, Ageliki Kokkini, Stavrina Avgeropoulou, Argyro Hadjioannou, Efgenia Anastasakou, Antonis Rasidakis and Petros Bakakos
    Citation: BMC Pulmonary Medicine 2009 9:11

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