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  1. Oxidative stress (OS) and reduced nitric oxide (NO) bioavailability contribute to the pathogenesis of pulmonary hypertension (PH). Whether there are associations between OS and NO signaling biomarkers and whet...

    Authors: Shuai Zhang, Ting Yang, Xiaomao Xu, Meng Wang, Linye Zhong, Yuanhua Yang, Zhenguo Zhai, Fei Xiao and Chen Wang
    Citation: BMC Pulmonary Medicine 2015 15:50
  2. Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to ass...

    Authors: Christina Tischer, Jan-Paul Zock, Maria Valkonen, Gert Doekes, Stefano Guerra, Dick Heederik, Deborah Jarvis, Dan Norbäck, Mario Olivieri, Jordi Sunyer, Cecilie Svanes, Martin Täubel, Elisabeth Thiering, Giuseppe Verlato, Anne Hyvärinen and Joachim Heinrich
    Citation: BMC Pulmonary Medicine 2015 15:48
  3. Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler®...

    Authors: Wahida Azouz, Philip Chetcuti, Harold Hosker, Dinesh Saralaya and Henry Chrystyn
    Citation: BMC Pulmonary Medicine 2015 15:47
  4. Neurohumoral activation is present in COPD and might provide a link between pulmonary and systemic effects, especially cardiovascular disease. Because long acting inhaled β-agonists reduce hyperinflation, they...

    Authors: Helge Haarmann, Cordula Mohrlang, Uta Tschiesner, David B Rubin, Thore Bornemann, Karin Rüter, Slavtcho Bonev, Tobias Raupach, Gerd Hasenfuß and Stefan Andreas
    Citation: BMC Pulmonary Medicine 2015 15:46
  5. Respiratory syncytial virus (RSV) lower respiratory tract infection (LRI) during infancy has been consistently associated with an increased risk of childhood asthma. In addition, evidence supports that this re...

    Authors: Emma K Larkin, Tebeb Gebretsadik, Martin L Moore, Larry J Anderson, William D Dupont, James D Chappell, Patricia A Minton, R Stokes Peebles Jr, Paul E Moore, Robert S Valet, Donald H Arnold, Christian Rosas-Salazar, Suman R Das, Fernando P Polack and Tina V Hartert
    Citation: BMC Pulmonary Medicine 2015 15:45
  6. COPD is largely under-diagnosed and once diagnosed usually at a late stage. Early diagnosis is thoroughly recommended but most attempts failed as the disease is marginally known and screening marginally accept...

    Authors: Nicolas Molinari, Mathieu Abou-Badra, Grégory Marin, Chin-Long Ky, Noemi Amador, Anne Sophie Gamez, Isabelle Vachier and Arnaud Bourdin
    Citation: BMC Pulmonary Medicine 2015 15:44
  7. Adherence to treatment is often reported to be low in children with cystic fibrosis. Adherence in cystic fibrosis is an important research area and more research is needed to better understand family barriers ...

    Authors: Nicola A Goodfellow, Ahmed F Hawwa, Alastair JM Reid, Rob Horne, Michael D Shields and James C McElnay
    Citation: BMC Pulmonary Medicine 2015 15:43
  8. Although asthma morbidity can be prevented through long-term controller medication, most patients with persistent asthma do not take their daily inhaled corticosteroid. The objective of this study was to gathe...

    Authors: Sandra Peláez, Alexandrine J Lamontagne, Johanne Collin, Annie Gauthier, Roland M Grad, Lucie Blais, Kim L Lavoie, Simon L Bacon, Pierre Ernst, Hélène Guay, Martha L McKinney and Francine M Ducharme
    Citation: BMC Pulmonary Medicine 2015 15:42
  9. Irisin, a recently discovered myokine, is assumed to be secreted by muscle cells in response to exercise and is involved in the regulation of energy metabolism by browning white adipose tissue cells. However, ...

    Authors: Nils Kerstholt, Ralf Ewert, Matthias Nauck, Thomas Spielhagen, Tom Bollmann, Beate Stubbe, Stephan B Felix, Henri Wallaschofski, Sven Gläser and Nele Friedrich
    Citation: BMC Pulmonary Medicine 2015 15:41
  10. Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by hypertension in the pulmonary arteries. PAH leads to symptoms such as shortness of breath, dizziness, leg edema and chest pain, ...

    Authors: Roselien Buys, Andrea Avila and Véronique A Cornelissen
    Citation: BMC Pulmonary Medicine 2015 15:40
  11. In adults, overweight is associated with reduced lung function, in children evidence on this association is conflicting. We examined the association of body mass index (BMI) and waist circumference (WC) at age...

    Authors: Marga B Bekkers, Alet H Wijga, Ulrike Gehring, Gerard H Koppelman, Johan C de Jongste, Henriette A Smit and Bert Brunekreef
    Citation: BMC Pulmonary Medicine 2015 15:39
  12. There is a paucity of clinical and histopathological data about HIV-associated lymphocytic interstitial pneumonitis (LIP) in adults from HIV endemic settings. The role of Ebstein-Barr virus (EBV) in the pathog...

    Authors: Richard N van Zyl-Smit, Jashira Naidoo, Helen Wainwright, Quanita Said-Hartley, Malika Davids, Hillel Goodman, Sean Rogers and Keertan Dheda
    Citation: BMC Pulmonary Medicine 2015 15:38
  13. The treatment landscape for idiopathic pulmonary fibrosis, a devastating lung disease, is changing. To investigate the effectiveness of treatments for idiopathic pulmonary fibrosis we undertook a systematic re...

    Authors: Emma Loveman, Vicky R Copley, David A Scott, Jill L Colquitt, Andrew J Clegg and Katherine MA O’Reilly
    Citation: BMC Pulmonary Medicine 2015 15:37
  14. The morbidity associated with severe uncontrolled asthma is disproportionately higher in low- and middle-income countries than in high-income countries. The aim of this study was to describe the phenotypic cha...

    Authors: Wenderson Clay Correia de Andrade, Laura Maria de Lima Belizário Facury Lasmar, Cristiane de Abreu Tonelli Ricci, Paulo Augusto Moreira Camargos and Álvaro A Cruz
    Citation: BMC Pulmonary Medicine 2015 15:36
  15. Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwi...

    Authors: Anders Juul Gullach, Bjarke Risgaard, Thomas Hadberg Lynge, Reza Jabbari, Charlotte Glinge, Stig Haunsø, Vibeke Backer, Bo Gregers Winkel and Jacob Tfelt-Hansen
    Citation: BMC Pulmonary Medicine 2015 15:35
  16. Thorax is the common place to develop Castleman disease (CD), but there is no systemic clinical analysis for intrathoracic CD.

    Authors: Jin mei Luo, Shan Li, Hui Huang, Jian Cao, Kai Xu, Ya lan Bi, Rui e Feng, Cheng Huang, Ying zhi Qin, Zuo jun Xu and Yi Xiao
    Citation: BMC Pulmonary Medicine 2015 15:34
  17. Skin prick tests (SPT) are widely used both in clinical diagnostics and in research. The standardization of allergen extracts is well documented to be crucial for the validity of SPT, whereas less emphasis has...

    Authors: Gert F Thomsen, Vivi Schlünssen, Lars R Skadhauge, Tine Halsen Malling, David L Sherson, Øyvind Omland and Torben Sigsgaard
    Citation: BMC Pulmonary Medicine 2015 15:33
  18. Deleted in malignant brain tumors 1 (DMBT1) is an innate defence protein expressed in the lungs of preterm infants and adults. Recent studies showed that DMBT1 is important in angiogenesis and can bind to differe...

    Authors: Hanna Müller, Christian Nagel, Christel Weiss, Jan Mollenhauer and Johannes Poeschl
    Citation: BMC Pulmonary Medicine 2015 15:32
  19. As part of an investigation into the respiratory health in children conducted in Torino, northwestern Italy, our aim was to assess development in lung function from childhood to adolescence, and to assess chan...

    Authors: Pavilio Piccioni, Roberta Tassinari, Aurelia Carosso, Carlo Carena, Massimiliano Bugiani and Roberto Bono
    Citation: BMC Pulmonary Medicine 2015 15:31
  20. Fibered confocal fluorescence microscopy (FCFM) allows in vivo investigation of pulmonary microstructures. However, the bronchial epithelium can only be imaged using exogenous fluorophores. The objective of this ...

    Authors: Bérengère Obstoy, Mathieu Salaun, Liana Veresezan, Richard Sesboüé, Pierre Bohn, François-Xavier Boland and Luc Thiberville
    Citation: BMC Pulmonary Medicine 2015 15:30
  21. The approach to palliative treatment of malignant pleural effusion (MPE) should be individualized because these patients generally have poor survival. Our study aimed to develop a model to identify prognostic ...

    Authors: Mauro Musa Zamboni, Cyro Teixeira da Silva Jr, Rodrigo Baretta, Edson Toscano Cunha and Gilberto Perez Cardoso
    Citation: BMC Pulmonary Medicine 2015 15:29
  22. Patients with pulmonary arteriovenous malformations usually complain of dyspnoea upon exertion, fatigue or migraine, or may be asymptomatic. We describe a patient with an unreported manifestation of a pulmonar...

    Authors: Etienne-Marie Jutant, Philippe Puyo, Mostafa El Hajjam, Sandra Blivet, Emmanuel Houdart, Michel Aubier, Pascal Lacombe and Thierry Chinet
    Citation: BMC Pulmonary Medicine 2015 15:28
  23. Pulmonary tularaemia is a very rare disease with only a small number of cases described in the literature. So far, to our knowledge, there exists no case report of pulmonary tularaemia where PET-CT scans and f...

    Authors: Patrick Fachinger, Gabrielo Mauro Tini, Rainer Grobholz, Franco Gambazzi, Hans Fankhauser and Sarosh Irani
    Citation: BMC Pulmonary Medicine 2015 15:27
  24. The Global Lung Function Initiative 2012 (GLI) reference values are currently endorsed by several respiratory societies but evaluations of applicability for adults resident in European countries are lacking. T...

    Authors: Helena Backman, Anne Lindberg, Anssi Sovijärvi, Kjell Larsson, Bo Lundbäck and Eva Rönmark
    Citation: BMC Pulmonary Medicine 2015 15:26
  25. Congenital thoracic malformations (CTM) are rare lung lesions that are managed with surgical resection or active surveillance.

    Authors: Payal H Mandaliya, Matthew Morten, Rajendra Kumar, Alan James, Aniruddh Deshpande, Vanessa E Murphy, Peter G Gibson, Bruce Whitehead, Paul Robinson and Joerg Mattes
    Citation: BMC Pulmonary Medicine 2015 15:25
  26. Polysomnography (PSG) is treated as the gold standard for diagnosing obstructive sleep apnea (OSA). However, it is labor-intensive, time-consuming, and expensive. This study evaluates validity of overnight pul...

    Authors: Liang-Wen Hang, Hsiang-Ling Wang, Jen-Ho Chen, Jiin-Chyr Hsu, Hsuan-Hung Lin, Wei-Sheng Chung and Yung-Fu Chen
    Citation: BMC Pulmonary Medicine 2015 15:24
  27. Recent literature shows that there is a large mismatch between the US patients’ expected duration of acute cough illness and the actual duration. It has been suggested that this discrepancy may lead to antibio...

    Authors: Tai Pong Lam, Kwok Fai Lam, Yuk Tsan Wun and Kai Sing Sun
    Citation: BMC Pulmonary Medicine 2015 15:23
  28. We studied the value of routine biochemical variables albumin, C-reactive protein (CRP) and lactate dehydrogenase (LDH) to improve prediction and monitoring of acute respiratory distress syndrome (ARDS) severi...

    Authors: Sandra H Hoeboer, Heleen M Oudemans-van Straaten and AB Johan Groeneveld
    Citation: BMC Pulmonary Medicine 2015 15:22
  29. To evaluate the factors affecting the maximum standardized uptake value (SUVmax) of metastatic lymph nodes in different histological types of non-small cell lung cancer (NSCLC) on integrated positron emission ...

    Authors: Yuehong Wang, Shanni Ma, Mengjie Dong, Yake Yao, Kanfeng Liu and Jianying Zhou
    Citation: BMC Pulmonary Medicine 2015 15:20
  30. Secretory leukocyte protease inhibitor (SLPI) is a protein with anti-protease and antimicrobial properties that is constitutively secreted from the airway epithelium. The importance of maintaining a balance be...

    Authors: Lisa I Påhlman, Annika Jögi, Magnus Gram, Michiko Mori and Arne Egesten
    Citation: BMC Pulmonary Medicine 2015 15:19
  31. Argan is now used worldwide in numerous cosmetic products. Nine workers from a cosmetic factory were examined in our occupational medicine department, following the diagnosis of a case of hypersensitivity pneu...

    Authors: Christophe Paris, Fabrice Herin, Gabriel Reboux, Emmanuelle Penven, Coralie Barrera, Cécile Guidat and Isabelle Thaon
    Citation: BMC Pulmonary Medicine 2015 15:18
  32. Asthma is the most common chronic condition of childhood and disproportionately affects inner-city minority children. Low rates of asthma preventer medication adherence is a major contributor to poor asthma co...

    Authors: John M Wiecha, William G Adams, Denis Rybin, Maria Rizzodepaoli, Jeremy Keller and Jayanti M Clay
    Citation: BMC Pulmonary Medicine 2015 15:17
  33. The prevalence of diagnosed chronic obstructive pulmonary disease (COPD) in the UK is 1.8%, although it is estimated that this represents less than half of the total disease in the population as much remains u...

    Authors: Manbinder S Sidhu, Amanda Daley, Rachel Jordan, Peter A Coventry, Carl Heneghan, Sue Jowett, Sally Singh, Jennifer Marsh, Peymane Adab, Jinu Varghese, David Nunan, Amy Blakemore, Jenny Stevens, Lee Dowson, David Fitzmaurice and Kate Jolly
    Citation: BMC Pulmonary Medicine 2015 15:16
  34. Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has an extremely poor prognosis and there is currently no effective treatment for this condition. Direct hemoperfusion with a polymyxin B-immobilize...

    Authors: Noriyuki Enomoto, Masashi Mikamo, Yoshiyuki Oyama, Masato Kono, Dai Hashimoto, Tomoyuki Fujisawa, Naoki Inui, Yutaro Nakamura, Hideo Yasuda, Akihiko Kato, Soichiro Mimuro, Matsuyuki Doi, Shigehito Sato and Takafumi Suda
    Citation: BMC Pulmonary Medicine 2015 15:15
  35. Interleukin-27 (IL-27) is a multifunctional cytokine with both pro-inflammatory and immunoregulatory functions. At present, the role of IL-27 in pulmonary fibrosis remains unknown.

    Authors: Zhaoxing Dong, Xin Lu, Yanni Yang, Tao Zhang, Yongxia Li, Yanlin Chai, Wen Lei, Changbo Li, Li Ai and Wenlin Tai
    Citation: BMC Pulmonary Medicine 2015 15:13
  36. Asthma is characterized by airway hyper-responsiveness and variable airflow obstruction, in part as a consequence of hyper-contractile airway smooth muscle, which persists in primary cell culture. One potentia...

    Authors: David Sweeney, Fay Hollins, Edith Gomez, Rajendra Mistry, Ruth Saunders, Robert Alfred John Challiss and Christopher Edward Brightling
    Citation: BMC Pulmonary Medicine 2015 15:12
  37. Patients with precapillary pulmonary hypertension (PH) have been reported to suffer from poor sleep quality, however, if this is related to physical exercise performance has not yet been thoroughly investigated.

    Authors: Henning Tiede, Janet Rorzyczka, Rio Dumitrascu, Michael Belly, Frank Reichenberger, Hossein Ardeschir Ghofrani, Werner Seeger, Jörg Heitmann and Richard Schulz
    Citation: BMC Pulmonary Medicine 2015 15:11
  38. Chronic respiratory diseases are a significant cause of morbidity and mortality worldwide. We sought to evaluate the impact of asthma, chronic bronchitis and allergic rhinitis on all-cause hospitalizations and...

    Authors: Simone Accordini, Angelo Guido Corsico, Lucia Calciano, Roberto Bono, Isa Cerveri, Alessandro Fois, Pietro Pirina, Roberta Tassinari, Giuseppe Verlato and Roberto de Marco
    Citation: BMC Pulmonary Medicine 2015 15:10
  39. GATA-2 transcription factor deficiency has recently been described in patients with a propensity towards myeloid malignancy associated with other highly variable phenotypic features: chronic leukocytopenias (d...

    Authors: Tamara Svobodova, Ester Mejstrikova, Ulrich Salzer, Martina Sukova, Petr Hubacek, Radoslav Matej, Martina Vasakova, Ludmila Hornofova, Marcela Dvorakova, Eva Fronkova, Felix Votava, Tomas Freiberger, Petr Pohunek, Jan Stary and Ales Janda
    Citation: BMC Pulmonary Medicine 2015 15:8
  40. The lectin-like domain of TNF-α can be mimicked by synthetic TIP peptides and represents an innovative pharmacologic option to treat edematous respiratory failure. TIP inhalation was shown to reduce pulmonary ...

    Authors: Erik K Hartmann, Alexander Ziebart, Rainer Thomas, Tanghua Liu, Arno Schad, Martha Tews, Bernd Moosmann, Jens Kamuf, Bastian Duenges, Serge C Thal and Matthias David
    Citation: BMC Pulmonary Medicine 2015 15:7
  41. Antibiotic-resistant strains of pathogenic bacteria are increasingly prevalent in hospitals and the community. Acute exacerbations of COPD (AE-COPD) often result in administration of antibiotics although more ...

    Authors: Gernot G U Rohde, Armin Koch and Tobias Welte
    Citation: BMC Pulmonary Medicine 2015 15:5
  42. With the goal of reducing exposure to secondhand smoke, the state of Minnesota (MN), enacted a smoke-free law (i.e., Freedom to Breathe Act) in all workplaces, restaurants, and bars in 2007. This retrospective...

    Authors: Ivana T Croghan, Jon O Ebbert, J Taylor Hays, Darrell R Schroeder, Alanna M Chamberlain, Véronique L Roger and Richard D Hurt
    Citation: BMC Pulmonary Medicine 2015 15:6
  43. Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD.

    Authors: Eva Balcells, Elena Gimeno-Santos, Jordi de Batlle, Maria Antonia Ramon, Esther Rodríguez, Marta Benet, Eva Farrero, Antoni Ferrer, Stefano Guerra, Jaume Ferrer, Jaume Sauleda, Joan A Barberà, Àlvar Agustí, Robert Rodriguez-Roisin, Joaquim Gea, Josep M Antó…
    Citation: BMC Pulmonary Medicine 2015 15:4
  44. In recent years, patients with cystic fibrosis (CF) have tended to experience a longer life expectancy and higher quality of life. In this context, the aim of the present study was to evaluate and compare the ...

    Authors: Fernando Augusto de Lima Marson, Tais Daiene Russo Hortencio, Katia Cristina Alberto Aguiar and Jose Dirceu Ribeiro
    Citation: BMC Pulmonary Medicine 2015 15:3
  45. A variety of large randomized controlled trials (RCT’s) evaluating pharmacotherapy in chronic obstructive pulmonary disease (COPD) patients does exist. One of the drugs that has been tested is the new long-act...

    Authors: Peter Kardos, Claus Vogelmeier, Roland Buhl, Carl-Peter Criée and Heinrich Worth
    Citation: BMC Pulmonary Medicine 2015 15:2
  46. YKL-40 is also called chitinase-3-like-1 (CHI3L1) protein and may be a marker for asthma. The aims of the present study were to investigate whether serum YKL-40 levels are stable or decreased in patients with ...

    Authors: Tianwen Lai, Min Chen, Zaichun Deng, Yingying Lǚ, Dong Wu, Dongming Li and Bin Wu
    Citation: BMC Pulmonary Medicine 2015 15:1
  47. This study evaluated the effects of aclidinium bromide, a long-acting muscarinic antagonist indicated for maintenance treatment of chronic obstructive pulmonary disease (COPD), on exercise endurance, dyspnea, ...

    Authors: Kai M Beeh, Henrik Watz, Luis Puente-Maestu, Luis de Teresa, Diana Jarreta, Cynthia Caracta, Esther Garcia Gil and Helgo Magnussen
    Citation: BMC Pulmonary Medicine 2014 14:209

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