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  1. Acute exacerbation (AE) is the most lethal postoperative complication in idiopathic pulmonary fibrosis (IPF); however, prediction before surgery is difficult. We investigated the role of 18F-fluorodeoxyglucose po...

    Authors: Hee-Young Yoon, Suk Hyun Lee, Sejin Ha, Jin-Sook Ryu and Jin Woo Song
    Citation: BMC Pulmonary Medicine 2021 21:294
  2. Re-expansion pulmonary edema is an uncommon complication following drainage of a pneumothorax or pleural effusion. While pneumothorax is noted to complicate COVID-19 patients, no case of COVID-19 developing re...

    Authors: Kosaku Komiya, Ryosuke Hamanaka, Hisayuki Shuto, Hiroki Yoshikawa, Atsushi Yokoyama, Kazufumi Hiramatsu and Jun-ichi Kadota
    Citation: BMC Pulmonary Medicine 2021 21:293
  3. Asthma is a chronic inflammatory disorder of the airways involving many different factors. This study aimed to screen for the critical genes using DNA methylation/CpGs and miRNAs involved in childhood atopic a...

    Authors: Rui Chen, Li-Zhen Piao, Ling Liu and Xiao-Fei Zhang
    Citation: BMC Pulmonary Medicine 2021 21:292
  4. In recent years, the application of immunotherapy combined with chemotherapy in the first-line lung cancer has showed significant benefit in improving long-term survival. Immunotherapy also has risks of immune...

    Authors: Yu Feng, Cuncun Chen, Liming Zhao, Xuyou Zhu, Xiaoping Zhu and Qiang Li
    Citation: BMC Pulmonary Medicine 2021 21:291
  5. Chronic cough is characterized by cough as the only or main symptom, with a duration of more than 8 weeks and no obvious abnormality in chest X-ray examination. Its etiology is complex, including respiratory d...

    Authors: Jiaofei Cao, Yue Hu, Shaojun Jin, Fei Chen, Li Li and Huaqiong Huang
    Citation: BMC Pulmonary Medicine 2021 21:290
  6. Refractory dyspnea or breathlessness is a common symptom in patients with advanced chronic obstructive pulmonary disease (COPD), with a high negative impact on quality of life (QoL). Low dosed opioids have bee...

    Authors: Marlies van Dijk, Kris J. M. Mooren, Jan-Willem K. van den Berg, Wendy J. C. van Beurden-Moeskops, Roxane Heller-Baan, Sander M. de Hosson, Wai Yee Lam-Wong, Liesbeth Peters, Karin Pool and Huib A. M. Kerstjens
    Citation: BMC Pulmonary Medicine 2021 21:289
  7. Diffuse alveolar hemorrhage (DAH) is a syndrome resulting from bleeding in the microcirculation of the lung, with a poor prognosis. The study aim was to identify prognostic factors of DAH, especially bronchoal...

    Authors: Kensuke Kanaoka, Seigo Minami, Shoichi Ihara and Kiyoshi Komuta
    Citation: BMC Pulmonary Medicine 2021 21:288
  8. Lung adenocarcinoma (LUAD) is the most common histological subtype of primary lung cancer. To identify the biomarker of diagnosis for LUAD is of great significance. Long non-coding RNAs (lncRNAs) were previous...

    Authors: Wen Huang, Xinxing Wang, Fubing Wu and Fanggui Xu
    Citation: BMC Pulmonary Medicine 2021 21:287
  9. In the treatment of lung cancer, the presence or absence of mediastinal lymph node involvement has a significant bearing on the indication for surgery. In addition, if a tumor is found in the trachea during pr...

    Authors: Yutaka Takahara, Kouichi Yamamura, Nozomu Motono, Taku Oikawa, Hidetaka Uramoto and Shiro Mizuno
    Citation: BMC Pulmonary Medicine 2021 21:286
  10. Oxygen therapy is routinely administered to mechanically ventilated patients. However, there remains uncertainty about the optimal oxygen titration target in patients with the acute respiratory distress syndro...

    Authors: Andrew J. Boyle, David N. Holmes, Jonathan Hackett, Susanna Gilliland, Michael McCloskey, Cecilia M. O’Kane, Paul Young, Stefania Di Gangi and Daniel F. McAuley
    Citation: BMC Pulmonary Medicine 2021 21:285
  11. Treatment for non-small cell lung cancer (NSCLC) has greatly improved in recent years. However, noninvasive early screening for carcinogenesis and progression unclear. The aim of this study was to explore the ...

    Authors: Yingyi Wang, Na Zhou, Rui Zhu, Xiaoyuan Li, Zhao Sun, Yang Gao, Wei Liu, Changting Meng, Yuping Ge, Chunmei Bai, Taisheng Li and Hongsheng Liu
    Citation: BMC Pulmonary Medicine 2021 21:282
  12. There is a lack of clinical-radiological predictive models for the small (≤ 20 mm) solitary pulmonary nodules (SPNs). We aim to establish a clinical-radiological predictive model for differentiating malignant ...

    Authors: Hai-Cheng Zhao, Qing-Song Xu, Yi-Bing Shi and Xi-Juan Ma
    Citation: BMC Pulmonary Medicine 2021 21:281
  13. Identifying or prioritizing genes for chronic obstructive pulmonary disease (COPD), one type of complex disease, is particularly important for its prevention and treatment.

    Authors: Wan Li, Yihua Zhang, Yahui Wang, Zherou Rong, Chenyu Liu, Hui Miao, Hongwei Chen, Yuehan He, Weiming He and Lina Chen
    Citation: BMC Pulmonary Medicine 2021 21:280
  14. There are various reasons for delayed positive nasopharyngeal PCR tests for coronavirus disease 2019 (COVID19) in not only asymptomatic but also severely diseased patients. The pathophysiological attributes ar...

    Authors: Lei Zhang, Syam P. Vunnamadala, Shigeo Yagi, Riffat Meraj and Michele Carbone
    Citation: BMC Pulmonary Medicine 2021 21:278
  15. LncRNA DLGAP1-AS2 plays an oncogenic role in glioma, while its role in other cancers is unknown. This study aimed to study the role of DLGAP1-AS2 in non-small cell lung cancer (NSCLC).

    Authors: Lu Wang, Lei Tang, Tengfei Ge, Feng Zhu, Dan Liu, Hua Guo, Peng Qian and Ning Xu
    Citation: BMC Pulmonary Medicine 2021 21:277
  16. How cigarette smoke (CS) and chronic obstructive pulmonary disease (COPD) affect severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection and severity is controversial. We investigated the effects...

    Authors: M. Tomchaney, M. Contoli, J. Mayo, S. Baraldo, S. Li, C. R. Cabel, D. A. Bull, S. Lick, J. Malo, S. Knoper, S. S. Kim, J. Tram, J. Rojas-Quintero, M. Kraft, J. G. Ledford, Y. Tesfaigzi…
    Citation: BMC Pulmonary Medicine 2021 21:275
  17. Transbronchial lung cryobiopsy is a safe technique increasingly used in the study of lung diseases. Until now, only a case of pneumatocele was described but this interesting condition is probably underestimate...

    Authors: Roberto Piro, Sofia Taddei, Matteo Fontana, Chiara Scelfo, Eleonora Casalini and Nicola Facciolongo
    Citation: BMC Pulmonary Medicine 2021 21:274
  18. Within the pathogenesis of the chronic obstructive pulmonary disease (COPD) there are interactions between different inflammatory mediators that are enhanced during an exacerbation. Arginase is present in bron...

    Authors: Marcel Jose Rodríguez-Guzmán, Germán Peces-Barba Romero, Sandra Pérez Rial, Cristina Serrano del Castillo, Miguel Ángel Palomero Rodríguez, Ignacio Mahillo-Fernandez and Felipe Villar-Álvarez
    Citation: BMC Pulmonary Medicine 2021 21:271
  19. Adult patients with cystic fibrosis (CF) experience daily physical symptoms and disabilities that can be challenging to address for health care teams.

    Authors: Sandra Dury, Jeanne-Marie Perotin, Bruno Ravoninjatovo, Catherine Llerena, Julien Ancel, Pauline Mulette, Muriel Griffon, Sophie Carré, Amélie Perrin, François Lebargy, Gaëtan Deslée and Claire Launois
    Citation: BMC Pulmonary Medicine 2021 21:270
  20. Bronchiectasis is a major contributor to respiratory morbidity and healthcare utilization in children. Children with bronchiectasis exhibit low levels of physical activity (PA) and poor fundamental movement sk...

    Authors: Barbara Joschtel, Sjaan R. Gomersall, Sean Tweedy, Helen Petsky, Anne B. Chang and Stewart G. Trost
    Citation: BMC Pulmonary Medicine 2021 21:269
  21. Curcumin, a derivative of the spice turmeric, has been adopted by Eastern medicine for centuries as an adjunct to treat several medical conditions (e.g., anorexia and arthritis) because of its well-established...

    Authors: Michele Quan, Abdullah Alismail, Noha Daher, Derrick Cleland, Sonia Chavan and Laren D. Tan
    Citation: BMC Pulmonary Medicine 2021 21:268
  22. The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairme...

    Authors: Álvaro Mingote, Andrea Albajar, Paulino García Benedito, Jessica Garcia-Suarez, Paolo Pelosi, Lorenzo Ball and Javier García-Fernández
    Citation: BMC Pulmonary Medicine 2021 21:267
  23. Incorrect use of inhalers among asthma and COPD patients is very prevalent. Yet, no single intervention is considered standard of care. We aimed to conduct a COPD-specific investigation of active one-on-one co...

    Authors: Jin Sun Kim, Nader Hashweh, Hannah Li, Salik Choudhary, Sadashiv Santosh and Edward Charbek
    Citation: BMC Pulmonary Medicine 2021 21:266
  24. The objective of the present study is to describe the clinical, diagnostic, radiological and therapeutic aspects of osteoarticular tuberculosis (OATB) in patients in a tertiary pediatric hospital, to know if t...

    Authors: Napoleón González Saldaña, Mercedes Macías Parra, Luis Xochihua Díaz, Martin Palavicini Rueda, Ana Jocelyn Carmona Vargas, José Iván Castillo Bejarano, Quetzalli Veloz Corona, Hugo Juárez Olguín and Juan Luis Chavez Pacheco
    Citation: BMC Pulmonary Medicine 2021 21:265
  25. Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by acute hypoxaemia, and few studies have reported the incidence of deep vein thrombosis (DVT) in direct ARDS caused by bacterial...

    Authors: Na Cui, Song Mi, Chunguo Jiang, Wanlu Sun, Wenping Mao, Liming Zhang and Xiaokai Feng
    Citation: BMC Pulmonary Medicine 2021 21:264
  26. Kartagener syndrome is a subtype of primary ciliary dyskinesia that may exhibit various symptoms including neonatal respiratory distress and frequent infections of the lung, sinus and middle ear because of the...

    Authors: Lina Wang, Xin Zhao, Hang Liang, Li Zhang, Chunyan Li, Deli Li, Xiangfeng Meng, Fanzheng Meng and Mao Gao
    Citation: BMC Pulmonary Medicine 2021 21:263
  27. While lung transplant (LTX) can be an effective therapy to provide the survival benefit in selected populations, post-transplant outcome in LTX recipients with bronchiectasis other than cystic fibrosis (CF) ha...

    Authors: Takashi Hirama, Fumiko Tomiyama, Hirotsugu Notsuda, Tatsuaki Watanabe, Yui Watanabe, Hisashi Oishi and Yoshinori Okada
    Citation: BMC Pulmonary Medicine 2021 21:261
  28. The 6th World Symposium on Pulmonary Hypertension (Nice 2018) proposed a new definition of pre-capillary pulmonary hypertension (PH) as a condition with mean pulmonary artery pressure (mPAP) > 20 mmHg, pulmona...

    Authors: Keiko Yamamoto, Nobuhiro Tanabe, Yukiko Takahashi, Akira Naito, Ayumi Sekine, Rika Suda, Takayuki Jujo Sanada, Toshihiko Sugiura, Ayako Shigeta, Seiichiro Sakao and Koichiro Tatsumi
    Citation: BMC Pulmonary Medicine 2021 21:260
  29. Tests to identify reversible airflow limitation are important in asthma diagnosis, but they are time-consuming and it may be difficult for patients to cooperate. We aimed to evaluate whether the combination of...

    Authors: Jiang-Hua Li, Rui Han, Yu-Bo Wang, Min Cheng, Heng-Yi Chen, Wen-Hui Lei, Li Li, Chen Gao, Na-Na Zhao, Nai-Fu Nie, Zhong-Yan Li, Guo-Qing Yin, Shuai Huang and Yong He
    Citation: BMC Pulmonary Medicine 2021 21:259
  30. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common presentation in emergency departments (ED) that can be fatal. This study aimed to develop a mortality risk assessment model for ...

    Authors: Lan Chen, Lijun Chen, Han Zheng, Sunying Wu and Saibin Wang
    Citation: BMC Pulmonary Medicine 2021 21:258
  31. We aim to analyze the risk factors for pneumothorax associated with computed tomography (CT)-guided percutaneous core needle biopsy (PCNB) of the lung. Whether the lung function characteristics are related to ...

    Authors: Chunhai Li, Dexiang Wang, Fengxia Yang, Yang Song, Xuejuan Yu, Bo Liu, Haipeng Jia and Wei Zhou
    Citation: BMC Pulmonary Medicine 2021 21:257
  32. Functional Respiratory Imaging (FRI) combines HRCT scans with computational fluid dynamics to provide objective and quantitative information about lung structure and function. FRI has proven its value in pulmo...

    Authors: Eline Lauwers, Annemiek Snoeckx, Kris Ides, Kim Van Hoorenbeeck, Maarten Lanclus, Wilfried De Backer, Jan De Backer and Stijn Verhulst
    Citation: BMC Pulmonary Medicine 2021 21:256
  33. Research on health-related quality of life (HRQL) has become increasingly important in recent decades. However, the impact of both living conditions and the level of autonomy impairments on HRQL in COPD patien...

    Authors: Sarah Bettina Schwarz, Tim Mathes, Daniel Sebastian Majorski, Maximilian Wollsching-Strobel, Doreen Kroppen, Friederike Sophie Magnet and Wolfram Windisch
    Citation: BMC Pulmonary Medicine 2021 21:255
  34. Aspiration pneumonitis is an inflammatory disease of the lungs which is difficult to diagnose accurately. Large-volume aspiration of oropharyngeal or gastric contents is essential for the development of aspira...

    Authors: Jiayu Cao, Wei Liu, Li Wang, Yujuan Yang, Yu Zhang and Xicheng Song
    Citation: BMC Pulmonary Medicine 2021 21:254
  35. Adherence to chronic obstructive pulmonary disease (COPD) maintenance medication is important for managing symptoms and exacerbation risk, and is associated with reduced mortality, hospitalizations, and costs....

    Authors: David Slade, Riju Ray, Chad Moretz, Guillaume Germain, François Laliberté, Qin Shen, Mei Sheng Duh, Malena Mahendran and Beth Hahn
    Citation: BMC Pulmonary Medicine 2021 21:253
  36. This study aimed to determine the effects of emodin on the viability, proliferation and apoptosis of human pulmonary artery smooth muscle cells (PASMCs) under hypoxia and to explore the underling molecular mec...

    Authors: Li Yi, JunFang Liu, Ming Deng, Huihua Zuo and Mingyan Li
    Citation: BMC Pulmonary Medicine 2021 21:252
  37. Systemic sclerosis (SSc) is a rare disease, and the presence of pulmonary hypertension can be a determining factor in prognosis. The aim of this study was to evaluate the diagnosis, profile, and prognosis of s...

    Authors: Verônica Silva Vilela, Marcio Macri Dias, Ângelo Antunes Salgado, Bruno Rangel Antunes da Silva, Agnaldo José Lopes, Elizabeth Jauhar Cardoso Bessa, Leonardo Palermo Bruno, Cláudia Henrique da Costa, Roger Abramino Levy and Rogério Rufino
    Citation: BMC Pulmonary Medicine 2021 21:251
  38. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) significantly increases the mortality of patients with COPD. Guidelines have recommended systemic glucocorticoid as a regular treatment. Rec...

    Authors: Qiu-Yu Li, Zhuo-Yu An, Zi-Han Pan and Rui-Ying Qi
    Citation: BMC Pulmonary Medicine 2021 21:250
  39. Treatment for interstitial lung disease (ILD) patients with acute respiratory failure (ARF) is challenging, and literature to guide such treatment is scarce. The reported in-hospital mortality rates of ILD pat...

    Authors: Johanna P. van Gemert, Inge A. H. van den Berk, Esther J. Nossent, Leo M. A. Heunks, Rene E. Jonkers, Alexander P. Vlaar and Peter I. Bonta
    Citation: BMC Pulmonary Medicine 2021 21:249
  40. Authors: Benoît Misset, Eric Hoste, Anne Françoise Donneau, David Grimaldi, Geert Meyfroidt, Michel Moutschen, Veerle Compernolle, André Gothot, Daniel Desmecht, Mutien Garigliany, Tome Najdovski and Pierre François Laterre
    Citation: BMC Pulmonary Medicine 2021 21:248

    The original article was published in BMC Pulmonary Medicine 2020 20:317

  41. Long non-coding RNAs (lncRNAs) play important roles in the development of pneumonia. We aimed to explore the role of the lncRNA KCNQ1OT1 in pneumonia and its underlying mechanisms.

    Authors: Ping Wang, Haitao Zhang, Weiqing Zhao and Nini Dai
    Citation: BMC Pulmonary Medicine 2021 21:247
  42. Observational studies show an association between reduced lung function and impaired cognition. Cognitive dysfunction influences important health outcomes and is a precursor to dementia, but treatments options...

    Authors: Daniel H. Higbee, Raquel Granell, Gibran Hemani, George Davey Smith and James W. Dodd
    Citation: BMC Pulmonary Medicine 2021 21:246
  43. Nintedanib reduces the rate of decline in forced vital capacity in patients with idiopathic pulmonary fibrosis (IPF), other chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype and ...

    Authors: Ulrike Schmid, Benjamin Weber, Celine Sarr and Matthias Freiwald
    Citation: BMC Pulmonary Medicine 2021 21:244

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