Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, et al. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nat Commun. 2018;9(1):2098–2098.
Article
Google Scholar
Sanford AM. Mild cognitive impairment. Clin Geriatr Med. 2017;33(3):325–37.
Article
Google Scholar
Jongsiriyanyong S, Limpawattana P. Mild cognitive impairment in clinical practice: a review article. Am J Alzheimers Dis Other Demen. 2018;33(8):500–7.
Article
Google Scholar
Agusti A, Noell G, Brugada J, Faner R. Lung function in early adulthood and health in later life: a transgenerational cohort analysis. Lancet Respir Med. 2017;5(12):935–45.
Article
Google Scholar
Dodd JW. Lung disease as a determinant of cognitive decline and dementia. Alzheimer’s Res Therapy. 2015;7(1):32.
Article
Google Scholar
Brunner EJ, Welch CA, Shipley MJ, Ahmadi-Abhari S, Singh-Manoux A, Kivimäki M. Midlife risk factors for impaired physical and cognitive functioning at older ages: a cohort study. J Gerontol A Biol Sci Med Sci. 2017;72(2):237–42.
Article
Google Scholar
Suglia SF, Wright RO, Schwartz J, Wright RJ. Association between lung function and cognition among children in a prospective birth cohort study. Psychosom Med. 2008;70(3):356–62.
Article
Google Scholar
Wen XH, Li Y, Han D, Sun L, Ren PX, Ren D. The relationship between cognitive function and arterial partial pressure O2 in patients with COPD: a meta-analysis. Medicine. 2018;97(4):e9599.
Article
CAS
Google Scholar
Liesker JJ, Postma DS, Beukema RJ, ten Hacken NH, van der Molen T, Riemersma RA, van Zomeren EH, Kerstjens HA. Cognitive performance in patients with COPD. Respir Med. 2004;98(4):351–6.
Article
Google Scholar
Bajaj MK, Burrage DR, Tappouni A, Dodd JW, Jones PW, Baker EH. COPD patients hospitalized with exacerbations have greater cognitive impairment than patients hospitalized with decompensated heart failure. Clin Interv Aging. 2019;14:1–8.
Article
CAS
Google Scholar
Chang SS, Chen S, McAvay GJ, Tinetti ME. Effect of coexisting chronic obstructive pulmonary disease and cognitive impairment on health outcomes in older adults. J Am Geriatr Soc. 2012;60(10):1839–46.
Article
Google Scholar
Campos MW, Serebrisky D, Castaldelli-Maia JM. Smoking and Cognition. Curr Drug Abuse Rev. 2016;9(2):76–9.
Article
CAS
Google Scholar
Corley J, Gow AJ, Starr JM, Deary IJ. Smoking, childhood IQ, and cognitive function in old age. J Psychosom Res. 2012;73(2):132–8.
Article
Google Scholar
Austin V, Crack PJ, Bozinovski S, Miller AA, Vlahos R. COPD and stroke: are systemic inflammation and oxidative stress the missing links? Clin Sci (Lond). 2016;130(13):1039–50.
Article
Google Scholar
Liao D, Higgins M, Bryan NR, Eigenbrodt ML, Chambless LE, Lamar V, Burke GL, Heiss G. Lower pulmonary function and cerebral subclinical abnormalities detected by MRI: the Atherosclerosis Risk in Communities study. Chest. 1999;116(1):150–6.
Article
CAS
Google Scholar
Smith GD, Ebrahim S. “Mendelian randomization”: can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol. 2003;32(1):1–22.
Article
Google Scholar
Davey Smith G, Hemani G. Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet. 2014;23(R1):R89–98.
Article
CAS
Google Scholar
Davey Smith G, Paternoster L, Relton C. When will mendelian randomization become relevant for clinical practice and public health? Mendelian randomization and clinical practice and public HealthEditorial. JAMA. 2017;317(6):589–91.
Article
Google Scholar
Sanderson E, Davey Smith G, Windmeijer F, Bowden J. An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings. Int J Epidemiol. 2018;48(3):713–27.
Article
Google Scholar
Higbee DH, Granell R, Sanderson E, Davey Smith G, Dodd JW. Lung function & cardiovascular disease. A two sample Mendelian randomisation study. Eur Respir J. 2021;2003196.
Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, et al. New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet. 2019;51(3):481–93.
Article
CAS
Google Scholar
Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, et al. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nat Genet. 2019;51(3):494–505.
Article
CAS
Google Scholar
Cohen-Manheim I, Doniger GM, Sinnreich R, Simon ES, Murad H, Pinchas-Mizrachi R, Kark JD. Body mass index, height and socioeconomic position in adolescence, their trajectories into adulthood, and cognitive function in midlife. J Alzheimers Dis. 2017;55(3):1207–21.
Article
Google Scholar
Aschard H, Vilhjálmsson Bjarni J, Joshi Amit D, Price Alkes L, Kraft P. Adjusting for heritable covariates can bias effect estimates in genome-wide association studies. Am J Hum Genet. 2015;96(2):329–39.
Article
CAS
Google Scholar
Leggett A, Clarke P, Zivin K, McCammon RJ, Elliott MR, Langa KM. Recent improvements in cognitive functioning among older U.S. adults: how much does increasing educational attainment explain? J Gerontol B Psychol Sci Soc Sci. 2019;74(3):536–45.
Article
Google Scholar
https://gwas.mrcieu.ac.uk/. 2020.
Hemani G, Tilling K, Davey Smith G. Orienting the causal relationship between imprecisely measured traits using GWAS summary data. PLoS Genet. 2017;13(11):e1007081.
Article
Google Scholar
Burgess S, Thompson SG, Collaboration CCG. Avoiding bias from weak instruments in Mendelian randomization studies. Int J Epidemiol. 2011;40(3):755–64.
Article
Google Scholar
Bowden J, Spiller W, Del Greco MF, Sheehan N, Thompson J, Minelli C, Davey Smith G. Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression. Int J Epidemiol. 2018;47(4):1264–78.
Article
Google Scholar
Smith GD, Ebrahim S. What can mendelian randomisation tell us about modifiable behavioural and environmental exposures? BMJ. 2005;330(7499):1076–9.
Article
Google Scholar
Portas L, Pereira M, Shaheen SO, Wyss AB, London SJ, Burney PGJ, Hind M, Dean CH, Minelli C. Lung development genes and adult lung function. Am J Respir Crit Care Med. 2020;202(6):853–65.
Article
CAS
Google Scholar
Wołoszynowska-Fraser MU, Kouchmeshky A, McCaffery P. Vitamin A and retinoic acid in cognition and cognitive disease. Annu Rev Nutr. 2020;40:247–72.
Article
Google Scholar
Burgess S, Labrecque JA. Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates. Eur J Epidemiol. 2018;33(10):947–52.
Article
Google Scholar
Vansteelandt S, Dukes O, Martinussen T. Survivor bias in Mendelian randomization analysis. Biostatistics. 2017;19(4):426–43.
Article
Google Scholar
Spilling CA, Bajaj MPK, Burrage DR, Ruickbie S, Thai NJ, Baker EH, Jones PW, Barrick TR, Dodd JW. Contributions of cardiovascular risk and smoking to chronic obstructive pulmonary disease (COPD)-related changes in brain structure and function. Int J Chron Obstruct Pulmon Dis. 2019;14:1855–66.
Article
CAS
Google Scholar
Trejo S, Domingue BW. Genetic nature or genetic nurture? Introducing social genetic parameters to quantify bias in polygenic score analyses. Biodemography Soc Biol. 2018;64(3–4):187–215.
Article
Google Scholar
Brumpton B, Sanderson E, Heilbron K, Hartwig FP, Harrison S, Vie G, Cho Y, Howe LD, Hughes A, Boomsma DI, et al. Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses. Nat Commun. 2020;11(1):3519.
Article
CAS
Google Scholar
Kraft P. Curses—winner’s and otherwise—in genetic epidemiology. Epidemiology. 2008;19(5):649–51.
Article
Google Scholar
Higbee DH, Dodd JW. Cognitive impairment in COPD: an often overlooked co-morbidity. Expert Rev Respir Med. 2021;15:9–11.
Article
CAS
Google Scholar