Galie N, Hoeper MM, Humbert M, Torbicky A, Vachiery JL, Barbera JA, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J. 2009;30:2493–537.
Article
PubMed
Google Scholar
Desai SA, Channick RN. Exercise in patients with pulmonary arterial hypertension. J Cardiopulm Rehabil Prev. 2008;28:12–6.
Article
PubMed
Google Scholar
Arena R, Lavie CJ, Milani RV, Myers J, Guazzi M. Cardiopulmonary exercise testing in patients with pulmonary arterial hypertension: an evidence-based review. J Heart Lung Transplant. 2010;29:159–73.
Article
PubMed
Google Scholar
Taylor RS, Sagar VA, Davies EJ, Briscoe S, Coats AJ, Ebrahim S, et al. Exercise-based rehabilitation for heart failure. Cochrane Database Syst Rev. 2014;4:CD003331.
PubMed
Google Scholar
Langer D, Hendriks E, Burtin C, Probst V, Van Der Schans C, Paterson W, et al. A clinical practice guideline for physiotherapists treating patients with chronic obstructive pulmonary disease based on a systematic review of available evidence. Clin Rehabil. 2009;23:445–62.
Article
CAS
PubMed
Google Scholar
Vanhees L, Rauch B, Piepoli M, Van Buuren F, Takken T, Börjesson M, et al. Importance of characteristics and modalities of physical activity and exercise in the management of cardiovascular health in individuals with cardiovascular disease (Part III). Eur J Prev Cardiol. 2012;19:1333–56.
Article
CAS
PubMed
Google Scholar
Duppen N, Takken T, Hopman MT, Ten Harkel AD, Dulfer K, Utens EM, et al. Systematic review of the effects of physical exercise training programmes in children and young adults with congenital heart disease. Int J Cardiol. 2013;168:3.
Article
Google Scholar
Physiotherapy evidence database (PEDro).[http://www.pedro.org.au]
de Morton NA. The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. Aust J Physiother. 2009;55:129–33.
Article
PubMed
Google Scholar
Maher CG, Sherrington C, Herbert RD, Moseley AM, Elkins M. Reliability of the PEDro scale for rating quality of randomized controlled trials. Phys Ther. 2003;83:713–21.
PubMed
Google Scholar
Follmann D, Elliott P, Suh I, Cutler J. Variance imputation for overviews of clinical trials with continuous response. J Clin Epidemiol. 1992;45:769–73.
Article
CAS
PubMed
Google Scholar
Dersimonian R, Kacker R. Random-effects model for meta-analysis of clinical trials: an update. Contemp Clin Trials. 2007;28:105–14.
Article
PubMed
Google Scholar
Schmidt FL, Oh IS, Hayes TL. Fixed- versus random-effects models in meta-analysis: model properties and an empirical comparison of differences in results. Br J Math Stat Psychol. 2009;62:97–128.
Article
PubMed
Google Scholar
Borenstein MHL, Higgins JPT, Rothstein HR. Introduction to meta-analysis. New York: John Wiley & Sons, Ltd; 2009. p. 272–92.
Book
Google Scholar
Chan L, Chin LM, Kennedy M, Woolstenhulme JG, Nathan SD, Weinstein AA, et al. Benefits of intensive treadmill exercise training on cardiorespiratory function and quality of life in patients with pulmonary hypertension. Chest. 2013;143:333–43.
Article
PubMed
Google Scholar
Weinstein AA, Chin LM, Keyser RE, Kennedy M, Nathan SD, Woolstenhulme JG, et al. Effect of aerobic exercise training on fatigue and physical activity in patients with pulmonary arterial hypertension. Respir Med. 2013;107:778–84.
Article
PubMed
PubMed Central
Google Scholar
Martinez-Quintana E, Miranda-Calderin G, Ugarte-Lopetegui A, Rodriguez-Gonzalez F. Rehabilitation program in adult congenital heart disease patients with pulmonary hypertension. Congenit Heart Dis. 2010;5:44–50.
Article
PubMed
Google Scholar
Mereles D, Ehlken N, Kreuscher S, Ghofrani S, Hoeper MM, Halank M, et al. Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation. 2006;114:1482–9.
Article
PubMed
Google Scholar
Fox BD, Kassirer M, Weiss I, Raviv Y, Peled N, Shitrit D, et al. Ambulatory rehabilitation improves exercise capacity in patients with pulmonary hypertension. J Card Fail. 2011;17:196–200.
Article
PubMed
Google Scholar
Ley S, Fink C, Risse F, Ehlken N, Fischer C, Ley Zaporozhan J, et al. Magnetic resonance imaging to assess the effect of exercise training on pulmonary perfusion and blood flow in patients with pulmonary hypertension. Eur Radiol. 2013;23:324–31.
Article
PubMed
Google Scholar
ATS statement. Guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166:111–7.
Article
Google Scholar
Lacasse Y, Brosseau L, Milne S, Martin S, Wong E, Guyatt GH, et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2002;3:CD003793.
PubMed
Google Scholar
Peytremann-Bridevaux I, Staeger P, Bridevaux PO, Ghali WA, Burnand B. Effectiveness of chronic obstructive pulmonary disease-management programs: systematic review and meta-analysis. Am J Med. 2008;121:433–43.
Article
PubMed
Google Scholar
Van der Meer S, Zwerink M, van Brussel M, van der Valk P, Wajon E, van der Palen J. Effect of outpatient exercise training programmes in patients with chronic heart failure: a systematic review. Eur J Prev Cardiol. 2012;19(4):795–803.
Article
PubMed
Google Scholar
Rasekaba T, Lee AL, Naughton MT, Williams TJ, Holland AE. The six-minute walk test: a useful metric for the cardiopulmonary patient. Intern Med J. 2009;39:495–501.
Article
CAS
PubMed
Google Scholar
Savarese G, Paolillo S, Costanzo P,D, Amore C, Cecere M, Losco T, et al. Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials. J Am Coll Cardiol. 2012;60:1192–201.
Article
PubMed
Google Scholar
Macchia A, Marchioli R, Marfisi R, Scarano M, Levantesi G, Tavazzi L, et al. A meta-analysis of trials of pulmonary hypertension: a clinical condition looking for drugs and research methodology. Am Heart J. 2007;153:1037–47.
Article
PubMed
Google Scholar
Golpe R, Castro-Anon O, Perez-de-Llano LA, Gonzalez Juanatey C, Muniz Fernandez C, Testa Fernandez A, et al. Prognostic significance of six-minute walk test in non-group 1 pulmonary hypertension. Heart Lung. 2014;43:72–6.
Article
PubMed
Google Scholar
Hansen JE, Sun XG, Yasunobu Y, Garafano RP, Gates G, Barst RJ, et al. Reproducibility of cardiopulmonary exercise measurements in patients with pulmonary arterial hypertension. Chest. 2004;126:816–24.
Article
PubMed
Google Scholar
Paolillo S, Farina S, Bussotti M, Iorio A, PerroneFilardi P, Piepolil MF, et al. Exercise testing in the clinical management of patients affected by pulmonary arterial hypertension. Eur J Prev Cardiol. 2012;19:960–71.
Article
PubMed
Google Scholar
Zafrir B. Exercise training and rehabilitation in pulmonary arterial hypertension: rationale and current data evaluation. J Cardiopulm Rehabil Prev. 2013;33:263–73.
Article
PubMed
Google Scholar
Groepenhoff H, Vonk-Noordegraaf A, van de Veerdonk MC, Boonstra A, Westerhof N, Bogaard HJ. Prognostic relevance of changes in exercise test variables in pulmonary arterial hypertension. PLoS One. 2013;8:e72013.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chua R, Keogh AM, Byth K, O’Loughlin A. Comparison and validation of three measures of quality of life in patients with pulmonary hypertension. Intern Med J. 2006;36:705–10.
Article
CAS
PubMed
Google Scholar
Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration. BMJ. 2009;339:b2700.
Article
PubMed
PubMed Central
Google Scholar
Fagard RH, Staessen JA, Thijs L. Advantages and disadvantages of the meta-analysis approach. J Hypertens Suppl. 1996;14:S9–12.
Article
CAS
PubMed
Google Scholar