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  1. Idiopathic pulmonary fibrosis (IPF) is a chronic, lethal disease of which the etiology is still not fully understood. Current treatment comprises two FDA-approved drugs that can slow down yet not stop or rever...

    Authors: Agnes W. Boots, Carmen Veith, Catrin Albrecht, Roger Bartholome, Marie-José Drittij, Sandra M. H. Claessen, Aalt Bast, Martin Rosenbruch, Leonie Jonkers, Frederik-Jan van Schooten and Roel P. F. Schins

    Citation: BMC Pulmonary Medicine 2020 20:112

    Content type: Research article

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  2. Inhaled bronchodilators including long-acting beta-agonist (LABA) and long-acting muscarinic antagonist (LAMA) play a central role in the treatment of stable chronic obstructive pulmonary disease (COPD). Howev...

    Authors: Akira Koarai, Hisatoshi Sugiura, Mitsuhiro Yamada, Tomohiro Ichikawa, Naoya Fujino, Tomotaka Kawayama and Masakazu Ichinose

    Citation: BMC Pulmonary Medicine 2020 20:111

    Content type: Research article

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  3. Infection is the most common cause of mortality within the first year after lung transplantation (LTx). The management of perioperative antibiotic therapy is a major issue, but little is known about worldwide ...

    Authors: Benjamin Coiffard, Eloi Prud’Homme, Sami Hraiech, Nadim Cassir, Jérôme Le Pavec, Romain Kessler, Federica Meloni, Marc Leone, Pascal Alexandre Thomas, Martine Reynaud-Gaubert and Laurent Papazian

    Citation: BMC Pulmonary Medicine 2020 20:109

    Content type: Research article

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  4. The epidemiology of acute kidney injury (AKI) in nonexacerbated chronic obstructive pulmonary disease (NECOPD) patients is unknown. This study investigated the factors associated with AKI and the association b...

    Authors: Xiaohong Wang, Zhen Xie, Shuguang Xiong, Wei Xiong, Tian Zhong and Yang Su

    Citation: BMC Pulmonary Medicine 2020 20:108

    Content type: Research article

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  5. To investigate whether, in patients hospitalized for COPD, the addition of social factors improves the predictive ability for the risk of overall 30-day readmissions, early readmissions (within 7 days after di...

    Authors: Tadahiro Goto, Kazuki Yoshida, Mohammad Kamal Faridi, Carlos A. Camargo Jr and Kohei Hasegawa

    Citation: BMC Pulmonary Medicine 2020 20:107

    Content type: Research article

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  6. Mechanical ventilation (MV), compared to spontaneous breathing (SB), has been found to increase abdominal edema and inflammation in experimental sepsis. Our hypothesis was that in primary acute respiratory dis...

    Authors: Silvia Marchesi, Göran Hedenstierna, Aki Hata, Ricardo Feinstein, Anders Larsson, Anders Olof Larsson and Miklós Lipcsey

    Citation: BMC Pulmonary Medicine 2020 20:106

    Content type: Research article

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  7. WHO’s directly observed therapy (DOT) strategy for tuberculosis (TB) treatment depends upon a well–organized healthcare system. This study sought to evaluate the effectiveness of self-administered drug intake ...

    Authors: Vahe Khachadourian, Nune Truzyan, Arusyak Harutyunyan, Varduhi Petrosyan, Hayk Davtyan, Karapet Davtyan, Martin van den Boom and Michael E. Thompson

    Citation: BMC Pulmonary Medicine 2020 20:105

    Content type: Research article

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  8. Immune checkpoint inhibitors (ICIs) are the standard treatment for non-small cell lung cancer. The unique adverse events that can arise after treatment with ICIs are known as immune-related adverse events (irA...

    Authors: Takeshi Terashima, Eri Iwami, Takashi Shimada, Aoi Kuroda, Tatsu Matsuzaki, Takahiro Nakajima, Aya Sasaki and Keisuke Eguchi

    Citation: BMC Pulmonary Medicine 2020 20:104

    Content type: Case report

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  9. Chronic obstructive pulmonary disease (COPD) patients with different phenotypes show different clinical characteristics. Therefore, we conducted a meta-analysis to explore the clinical characteristics between ...

    Authors: Jian-jun Wu, Hong-ri Xu, Ying-xue Zhang, Yi-xuan Li, Hui-yong Yu, Liang-duo Jiang, Cheng-xiang Wang and Mei Han

    Citation: BMC Pulmonary Medicine 2020 20:103

    Content type: Research article

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  12. The tracheobronchomalacia is a life-threatening complication of mucopolysaccharidosis (MPS) without known effective, optimal treatment. The severe expiratory collapse of the trachea and bronchi is one of cause...

    Authors: Wojciech Gocyk, Janusz Warmus, Henryk Olechnowicz, Miroslaw Bik-Multanowski, Lukasz Pawlinski and Beata Kiec-Wilk

    Citation: BMC Pulmonary Medicine 2020 20:99

    Content type: Case report

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  13. Acute fibrinous and organizing pneumonitis (AFOP) is an uncommon variant of acute lung injury, characterized by intra-alveolar fibrin and organizing pneumonia. Proposed etiologies include connective tissue dis...

    Authors: Jiangnan Zhao, Yi Shi, Dongmei Yuan, Qunli Shi, Weiping Wang and Xin Su

    Citation: BMC Pulmonary Medicine 2020 20:98

    Content type: Case report

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  14. Spirometry is useful for evaluating respiratory health status and predicting health-related outcomes. As spirometry requires skilled technician and takes time, it is useful to find simple way for predicting lu...

    Authors: Makiko Kanai, Osamu Kanai, Kohei Fujita, Tadashi Mio and Masato Ito

    Citation: BMC Pulmonary Medicine 2020 20:97

    Content type: Research article

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  15. The prognostic value of elevated pretreatment platelet counts remains controversial in lung cancer patients. We performed the present meta-analysis to determine its precise role in these patients.

    Authors: Yuan Yuan, Hai Zhong, Liang Ye, Qian Li, Surong Fang, Wei Gu and Yingying Qian

    Citation: BMC Pulmonary Medicine 2020 20:96

    Content type: Research article

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  16. Following publication of the original article [1], the authors flagged that the name provided for the 4th author had been misspelled; the 4th author was (incorrectly) spelled as ‘Eyob Alemayehu Gebreyohanns’.

    Authors: Tadesse Melaku Abegaz, Efrata Ashuro Shegena, Natnael Fentie Gessie, Eyob Alemayehu Gebreyohannes and Mohammed Assen Seid

    Citation: BMC Pulmonary Medicine 2020 20:95

    Content type: Correction

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    The original article was published in BMC Pulmonary Medicine 2020 20:48

  17. Malignant melanoma (MM) generally presents as a primary neoplasm of the skin, and most MM cases of the respiratory system are metastatic. Primary MM of the lung (PMML) is quite rare, and its diagnosis is relat...

    Authors: Shuangshuang Deng, Xiaobo Sun, Zhen Zhu, Jingjing Lu, Guanghua Wen, Xuejiao Chang, Hui Gao, Yanfei Hua, Lumei Wang and Jinli Gao

    Citation: BMC Pulmonary Medicine 2020 20:94

    Content type: Case report

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  18. Kartagener syndrome, an autosomal recessive disorder with a triad of chronic sinusitis, bronchiectasis, and situs inversus, is characterized by recurrent respiratory tract infections and chronic inflammation o...

    Authors: Yoshiaki Nagai, Nobuyuki Koyama, Yuki Iwai, Hiroyoshi Tsubochi, Masahiro Hiruta, Yoshiko Mizushina, Shinichiro Koyama, Yuichi Ishikawa and Koichi Hagiwara

    Citation: BMC Pulmonary Medicine 2020 20:93

    Content type: Case report

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  19. Obstructive sleep apnea (OSA) is associated with pulmonary fibrosis and endothelial apoptosis in pulmonary tissues. Chronic intermittent hypoxia (IH) is considered to be the primary player in OSA, but the mech...

    Authors: Zhihui Shi, Linhao Xu, Hui Xie, Ruoyun Ouyang, Ya Ke, Rui Zhou and Wing-Ho Yung

    Citation: BMC Pulmonary Medicine 2020 20:92

    Content type: Research article

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  20. The most prevalent complication of percutaneous lung biopsy is pneumothorax (PNX). A routine immediate post-procedure CT scan (ICT) to spot PNX is done in many centers. However, the diagnostic yield of this pr...

    Authors: Rafael Y. Brzezinski, Ifat Vigiser, Irina Fomin, Lilach Israeli, Shani Shenhar-Tsarfaty and Amir Bar-Shai

    Citation: BMC Pulmonary Medicine 2020 20:91

    Content type: Research article

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  22. At present, serum Aspergillus IgG and IgM antibody detection is mainly used in the diagnosis of chronic pulmonary aspergillosis (CPA), but its value in the diagnosis of invasive pulmonary aspergillosis (IPA) in n...

    Authors: Qihong Yu, Jingdong He, Bin Xing, Xin Li, Hongyu Qian, Hong Zhang, Meilin Xu and Haiying Peng

    Citation: BMC Pulmonary Medicine 2020 20:89

    Content type: Research article

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  23. Surprisingly little is known about asthma control among asthmatics who smoke. The aim of this cross-sectional study was to investigate asthma symptom control according to the GINA guidelines among asthmatics w...

    Authors: Toni Kiljander, Tuija Poussa, Timo Helin, Antero Jaakkola, Kari Venho and Lauri Lehtimäki

    Citation: BMC Pulmonary Medicine 2020 20:88

    Content type: Research article

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  24. The 12-week, multicentre, observational INITIAL study (NCT02143739) assessed asthma severity in newly diagnosed Chinese patients.

    Authors: Jiangtao Lin, Xiuhua Fu, Ping Jiang, Weidong Song, Xiaoyun Hu, Zhijun Jie, Chuntao Liu, Zhengguang He, Xiangdong Zhou and Huaping Tang

    Citation: BMC Pulmonary Medicine 2020 20:87

    Content type: Research article

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  25. Work-related respiratory disorders are major contributors to the global burden of respiratory diseases. Agricultural workers are exposed to a number of dusts, which may contribute to the development of respira...

    Authors: Gashaw Garedew Woldeamanuel, Alemu Basazin Mingude, Getachew Yideg Yitbarek and Mitku Mammo Taderegew

    Citation: BMC Pulmonary Medicine 2020 20:86

    Content type: Research article

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  26. NTP42 is a novel antagonist of the thromboxane prostanoid receptor (TP), currently in development for the treatment of pulmonary arterial hypertension (PAH). PAH is a devastating disease with multiple pathophysio...

    Authors: Eamon P. Mulvaney, Helen M. Reid, Lucia Bialesova, Annie Bouchard, Dany Salvail and B. Therese Kinsella

    Citation: BMC Pulmonary Medicine 2020 20:85

    Content type: Research article

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  27. Pulmonary alveolar proteinosis (PAP) is characterized by the accumulation of surfactant proteins within the alveolar spaces. Autoimmune PAP (APAP) caused by elevated levels of GM-CSF autoantibodies (GM-Ab) is ...

    Authors: S. Sato, K. Akasaka, H. Ohta, Y. Tsukahara, G. Kida, E. Tsumiyama, K. Kusano, T. Oba, T. Nishizawa, R. Kawabe, H. Yamakawa, M. Amano, H. Matsushima and T. Takada

    Citation: BMC Pulmonary Medicine 2020 20:84

    Content type: Case report

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  28. Antipseudomonal antibiotics should be restricted to patients at risk of Pseudomonas aeruginosa infection. However, the indications in different guidelines on community-acquired pneumonia (CAP) are discordant. Our...

    Authors: Nuria Angrill, Miguel Gallego, Juli Font, Jordi Vallés, Anisi Morón, Eduard Monsó and Jordi Rello

    Citation: BMC Pulmonary Medicine 2020 20:83

    Content type: Research article

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  29. Eosinophilic pleural effusion (EPE) is attributed to several well-recognised causes. However, some patients remain idiopathic, even after thorough clinical work-up. The present study aimed to better characteri...

    Authors: Weizhan Luo, Yunxiang Zeng, Panxiao Shen, Jianxing He and Jinlin Wang

    Citation: BMC Pulmonary Medicine 2020 20:82

    Content type: Research article

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  30. Numerous publications suggest an association between herpes virus infection and idiopathic pulmonary fibrosis (IPF). These reports have employed immunohistochemistry, in situ hybridization and/or PCR, which ar...

    Authors: Qinyan Yin, Michael J. Strong, Yan Zhuang, Erik K. Flemington, Naftali Kaminski, Joao A. de Andrade and Joseph A. Lasky

    Citation: BMC Pulmonary Medicine 2020 20:81

    Content type: Research article

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  31. Synchronous multiple primary lung cancers (sMPLC) are rare forms of lung cancer, and their diagnosis remains as a significant challenge. Distinguishing sMPLC from advanced disease is important as their prognos...

    Authors: Yang Song, Ziqi Jia, Pancheng Wu, Weiwei Wang, Qiuxiang Ou, Hua Bao, Man Yu, Xue Wu, Peng Liu, Naixin Liang, Shuyang Zhang and Shanqing Li

    Citation: BMC Pulmonary Medicine 2020 20:80

    Content type: Case report

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  32. The Asthma Control Test (ACT) has been used to assess asthma control in both clinical trials and clinical practice. However, the relationships between ACT score and other measures of asthma impact are not full...

    Authors: Bas C. P. van Dijk, Henrik Svedsater, Andreas Heddini, Linda Nelsen, Janita S. Balradj and Cathelijne Alleman

    Citation: BMC Pulmonary Medicine 2020 20:79

    Content type: Research article

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  34. Sarcoidosis is a systemic granulomatous disease caused by CD4+ cell-dominant inflammation. Meanwhile, diffuse panbronchiolitis is a chronic inflammatory respiratory disease predominantly caused by CD8+ lymphoc...

    Authors: Tomohiro Akaba, Kiyoshi Takeyama, Mitsuko Kondo, Fumi Kobayashi, Asako Okabayashi, Tatsuo Sawada and Etsuko Tagaya

    Citation: BMC Pulmonary Medicine 2020 20:77

    Content type: Case report

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  35. Hypoxia affects myocardial oxygen supply resulting in subclinical cardiac dysfunction in obstructive sleep apnea (OSA) patients, with cardiovascular complications being associated with increased oxidative burs...

    Authors: Antonello D’Andrea, Angelo Canora, Simona Sperlongano, Domenico Galati, Serena Zanotta, Giorgio Emanuele Polistina, Carmine Nicoletta, Giacomo Ghinassi, Maurizio Galderisi, Alessandro Sanduzzi Zamparelli, Patrizio Lancellotti and Marialuisa Bocchino

    Citation: BMC Pulmonary Medicine 2020 20:76

    Content type: Research article

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  36. Malignant tumors are risk factors for a pulmonary embolism (PE), and a PE caused by a tumor is not uncommon. Primary pleural squamous cell carcinoma (PPSCC) is a rare malignancy; thus, a related PE is extremel...

    Authors: Zhongzhong Chen, Tingting Feng, Meng Wang, Xingxiang Xu, Yuxiu Wang, Yiran Li and Lingfeng Min

    Citation: BMC Pulmonary Medicine 2020 20:75

    Content type: Case report

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  37. Chronic obstructive pulmonary disease (COPD) skeletal muscle dysfunction is a prevalent malady that significantly affects patients’ prognosis and quality of life. Although the study of this disease has attract...

    Authors: Jianqing Su, Jian Li, Yufan Lu, Ning Li, Peijun Li, Zhengrong Wang, Weibing Wu and Xiaodan Liu

    Citation: BMC Pulmonary Medicine 2020 20:74

    Content type: Research article

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  38. The discriminatory ability of multi-attribute utility (MAU) measures compared to condition-specific measures (CSM) in assessing health-related quality of life (HRQoL) among patients with chronic obstructive pu...

    Authors: Eunmi Bae, Sang-Eun Choi, Haeyoung Lee, Gyeongseon Shin and Daewon Kang

    Citation: BMC Pulmonary Medicine 2020 20:73

    Content type: Research article

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  39. Paracetamol and ibuprofen are the most commonly used medications for fever and pain management in children. While the efficacy appears similar with both drugs, there are contradictory findings related to adver...

    Authors: Mohamed Sherbash, Luis Furuya-Kanamori, Joanne Daghfal Nader and Lukman Thalib

    Citation: BMC Pulmonary Medicine 2020 20:72

    Content type: Research article

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  40. The concurrence of sarcoidosis and primary lung cancer is very rare. We report a very rare case with a delayed diagnosis of primary lung cancer due to its misdiagnosis as worsening of pulmonary sarcoidosis.

    Authors: Hong-Joon Shin, Min-Seok Kim, Bo Gun Kho, Ha Young Park, Tae-Ok Kim, Cheol-Kyu Park, In-Jae Oh, Yu-Il Kim, Young-Chul Kim, Yoo-Duk Choi and Sung-Chul Lim

    Citation: BMC Pulmonary Medicine 2020 20:71

    Content type: Case report

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  41. Pneumocystis jirovecii (P. jirovecii) is an opportunistic fungal pathogen and the role of its colonization in pulmonary diseases has become a popular focus in recent years. The aim of this study was to develop a ...

    Authors: Ting Xue, Zhuang Ma, Fan Liu, Weiqin Du, Li He, Jinyan Wang and Chunli An

    Citation: BMC Pulmonary Medicine 2020 20:70

    Content type: Research article

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  42. Lung cancer is one of the most common co-morbid conditions in patients with idiopathic pulmonary fibrosis (IPF) and negatively affects the prognosis of IPF; Current guidelines for the management of IPF do not ...

    Authors: Weirong Ma, Hui Li, Zhigang Tian, Shaojin Wang, Xiwei Zheng and Jia Hou

    Citation: BMC Pulmonary Medicine 2020 20:69

    Content type: Case report

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  43. Chronic cough has an important impact on physical, social and psychological aspects. A simple and effective method to assess different aspects of chronic cough severity is required. We aimed to develop a simpl...

    Authors: Wenzhi Zhan, Liting Zhang, Mei Jiang, Meihua Chen, Xiaoling Yuan, Jianxin Sun, Pusheng Xu, Feng Wu, Chunlai Zhang, Wei Luo, Xiaomei Chen, Hu Li and Kefang Lai

    Citation: BMC Pulmonary Medicine 2020 20:68

    Content type: Research article

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  44. Interstitial lung abnormalities (ILA) are common in participants of lung cancer screening trials and broad population-based cohorts. They are associated with increased mortality, but less is known about diseas...

    Authors: Nils Hoyer, Laura H. Thomsen, Mathilde M. W. Wille, Torgny Wilcke, Asger Dirksen, Jesper H. Pedersen, Zaigham Saghir, Haseem Ashraf and Saher B. Shaker

    Citation: BMC Pulmonary Medicine 2020 20:67

    Content type: Research article

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  45. Uncontrolled severe asthma in children is burdensome and challenging to manage. This study aims to describe outcomes in children with uncontrolled severe asthma managed in a nurse-led severe asthma clinic (SAC).

    Authors: Patricia de Gouveia Belinelo, Aleisha Nielsen, Bernadette Goddard, Lauren Platt, Carla Rebeca Da Silva Sena, Paul D. Robinson, Bruce Whitehead, Jodi Hilton, Tanya Gulliver, Laurence Roddick, Kasey Pearce, Vanessa E. Murphy, Peter G. Gibson, Adam Collison and Joerg Mattes

    Citation: BMC Pulmonary Medicine 2020 20:66

    Content type: Research article

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  46. Chlamydia psittaci pneumonia is a zoonotic infectious disease caused by Chlamydia psittaci. Diagnostic tools, including culture, serologic test and PCR-based methods, are available but prone to false negative res...

    Authors: Lei Gu, Wei Liu, Meng Ru, Jing Lin, Guoqing Yu, Jia Ye, Zheng-an Zhu, Yuebin Liu, Jian Chen, Guoxiang Lai and Wen Wen

    Citation: BMC Pulmonary Medicine 2020 20:65

    Content type: Case report

    Published on:

  47. Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) play important roles in the turnover of extracellular matrix and in the pathogenesis of idiopathic pulmonary fibrosis (IPF). This study ai...

    Authors: Jamie L. Todd, Richard Vinisko, Yi Liu, Megan L. Neely, Robert Overton, Kevin R. Flaherty, Imre Noth, L. Kristin Newby, Joseph A. Lasky, Mitchell A. Olman, Christian Hesslinger, Thomas B. Leonard, Scott M. Palmer and John A. Belperio

    Citation: BMC Pulmonary Medicine 2020 20:64

    Content type: Research article

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  48. Asthma is one of the conditions that contributes to the global burden of respiratory diseases and has been previously associated with diet intake. The goal of this study was to determine the relationship betwe...

    Authors: Carla E. Tarazona-Meza, Corrine Hanson, Suzanne L. Pollard, Karina M. Romero Rivero, Rocio M. Galvez Davila, Sameera Talegawkar, Carlos Rojas, Jessica L. Rice, William Checkley and Nadia N. Hansel

    Citation: BMC Pulmonary Medicine 2020 20:63

    Content type: Research article

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  49. Community-acquired pneumonia (CAP) requires urgent and specific antimicrobial therapy. However, the causal pathogen is typically unknown at the point when anti-infective therapeutics must be initiated. Physicia.....

    Authors: Claire Lhommet, Denis Garot, Leslie Grammatico-Guillon, Cassandra Jourdannaud, Pierre Asfar, Christophe Faisy, Grégoire Muller, Kimberly A. Barker, Emmanuelle Mercier, Sylvie Robert, Philippe Lanotte, Alain Goudeau, Helene Blasco and Antoine Guillon

    Citation: BMC Pulmonary Medicine 2020 20:62

    Content type: Research article

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  50. Factors associated with reduced daily physical activity (DPA) in patients with COPD are still controversial. Physical inactivity in COPD increases risk of cardiovascular disease, frequent exacerbations, reduce...

    Authors: Ali M. Albarrati, Nichola S. Gale, Maggie M. Munnery, John R. Cockcroft and Dennis J. Shale

    Citation: BMC Pulmonary Medicine 2020 20:60

    Content type: Research article

    Published on:

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