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Page 4 of 35

  1. Emphysema and chronic obstructive pulmonary disease (COPD) are well known independent risk factors for lung cancer. However, the developmental mechanisms between emphysema/COPD and lung cancer remain unknown. ...

    Authors: Ken Arimura, Yasuo Sekine, Kenzo Hiroshima, Satoru Shimizu, Noriyuki Shibata, Mitsuko Kondo, Kiyoshi Takeyama and Etsuko Tagaya

    Citation: BMC Pulmonary Medicine 2019 19:169

    Content type: Research article

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  2. The diagnosis of lung typical carcinoid tumors results challenging when limited size and unfavorable sampling location is associated. It has been reported that bronchoscopy with endobronchial ultrasound (EBUS)...

    Authors: Roberto Piro, Roberto Tonelli, Sofia Taddei, Alessandro Marchioni, Giovanni Musci, Enrico Clini and Nicola Facciolongo

    Citation: BMC Pulmonary Medicine 2019 19:168

    Content type: Case report

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  3. Pulmonary hypertension (PH) is traditionally defined as a resting mean pulmonary artery pressure (mPAP) of ≥25 mmHg, while mPAP in the range of 21 to 24 mmHg is recognized as “borderline PH.” Interstitial lung...

    Authors: Kenji Nemoto, Shuji Oh-ishi, Tatsuya Akiyama, Yuki Yabuuchi, Hitomi Goto, Mizu Nonaka, Yuika Sasatani, Hiroaki Tachi, Naoki Arai, Hiroaki Ishikawa, Kentaro Hyodo, Isano Hase, Yukiko Miura, Takio Takaku, Kenji Hayashihara and Takefumi Saito

    Citation: BMC Pulmonary Medicine 2019 19:167

    Content type: Research article

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  4. Myelolipoma is a rare benign tumor composed of mature adipose and hematopoietic tissues. Most myelolipomas are found in the adrenal glands, whereas intrathoracic myelolipoma is extremely rare. In particular, b...

    Authors: Hyun Sung Chung, Kyu Min Lee, Jung Seop Eom, Insu Kim, Seyeon Park, Jihyun Ahn, Ahrong Kim, Chang Hun Lee, Geewon Lee and Min Ki Lee

    Citation: BMC Pulmonary Medicine 2019 19:151

    Content type: Case report

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  5. Recent studies have highlighted the contribution of senescent mesenchymal and epithelial cells in Idiopathic Pulmonary Fibrosis (IPF), but little is known regarding the molecular mechanisms that regulate the a...

    Authors: David M. Habiel, Miriam S. Hohmann, Milena S. Espindola, Ana Lucia Coelho, Isabelle Jones, Heather Jones, Richard Carnibella, Isaac Pinar, Freda Werdiger and Cory M. Hogaboam

    Citation: BMC Pulmonary Medicine 2019 19:165

    Content type: Research article

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  6. Burkholderia contaminans is one of the 20 closely related bacterial of the Burkholderia cepacia complex, a group of bacteria that are ubiquitous in the environment and capable of infecting people with cystic fibr...

    Authors: Daniela Savi, Serena Quattrucci, Maria Trancassini, Claudia Dalmastri, Riccardo V. De Biase, Marta Maggisano, Paolo Palange and Annamaria Bevivino

    Citation: BMC Pulmonary Medicine 2019 19:164

    Content type: Case report

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  7. To compare the microbiological culture within endotracheal aspirate specimens (ETAs) and endotracheal tube specimens (ETTs) in patients undergoing mechanical ventilation (MV) by statistical tools.

    Authors: Lijuan Shen, Fei Wang, Junfeng Shi, Weixin Xu, Tingting Jiang, Huifang Tang, Xiuwen Yu, Hao Yin, Shanyou Hu, Xiao Wu, Siu Kit Chan, Jie Sun and Qing Chang

    Citation: BMC Pulmonary Medicine 2019 19:162

    Content type: Research article

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  8. CTD-related pleural effusions are rare and challenging to diagnose. Our lung inflammation service (with expertise in rheumatology, interstitial lung disease and respiratory failure) works closely with the pleu...

    Authors: Hugh Ip, Parthipan Sivakumar, Eugene Ace McDermott, Sangita Agarwal, Boris Lams, Alex West and Liju Ahmed

    Citation: BMC Pulmonary Medicine 2019 19:161

    Content type: Research article

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  9. Diaphragmatic assessment by ultrasound (US) is a non-invasive and useful method in the clinical management of patients with Amyotrophic Lateral Sclerosis (ALS). The aim of our observational study was to evalua...

    Authors: Riccardo Fantini, Roberto Tonelli, Ivana Castaniere, Luca Tabbì, Maria Rosaria Pellegrino, Stefania Cerri, Francesco Livrieri, Francesco Giaroni, Marco Monelli, Valentina Ruggieri, Nicola Fini, Jessica Mandrioli, Enrico Clini and Alessandro Marchioni

    Citation: BMC Pulmonary Medicine 2019 19:160

    Content type: Research article

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  10. Lung ultrasound (LUS) is nowadays a fast-growing field of study since the technique has been widely acknowledged as a cost-effective, radiation free, and ready available alternative to standard X-ray imaging. ...

    Authors: Danilo Buonsenso, Anna Maria Musolino, Antonio Gatto, Ilaria Lazzareschi, Antonietta Curatola and Piero Valentini

    Citation: BMC Pulmonary Medicine 2019 19:159

    Content type: Correspondence

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  11. Severe non-allergic eosinophilic asthma (SNEA) is a rare asthma phenotype associated with severe clinical course, frequent exacerbations, and resistance to therapy, including high steroid doses. The key featur...

    Authors: Virginija Kalinauskaite-Zukauske, Andrius Januskevicius, Ieva Janulaityte, Skaidrius Miliauskas and Kestutis Malakauskas

    Citation: BMC Pulmonary Medicine 2019 19:158

    Content type: Research article

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  12. Nintedanib is an inhibitor of receptor tyrosine kinases, including vascular endothelial growth factor receptor, but its effects on pulmonary hypertension (PH) in idiopathic pulmonary fibrosis (IPF) patients wi...

    Authors: Masahiro Tahara, Keishi Oda, Kei Yamasaki, Takako Kawaguchi, Konomi Sennari, Shingo Noguchi, Noriho Sakamoto, Toshinori Kawanami, Hiroshi Mukae and Kazuhiro Yatera

    Citation: BMC Pulmonary Medicine 2019 19:157

    Content type: Research article

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  13. Nintedanib is a tyrosine kinase inhibitor that efficiently slows the progression of idiopathic pulmonary fibrosis (IPF) and has an acceptable tolerability profile. In contrast, immune checkpoint inhibitors (IC...

    Authors: Hideaki Yamakawa, Tomohiro Oba, Hiroki Ohta, Yuta Tsukahara, Gen Kida, Emiri Tsumiyama, Tomotaka Nishizawa, Rie Kawabe, Shintaro Sato, Keiichi Akasaka, Masako Amano, Kazuyoshi Kuwano and Hidekazu Matsushima

    Citation: BMC Pulmonary Medicine 2019 19:156

    Content type: Case report

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  14. Endobronchial ultrasound-guided trans-bronchial needle aspiration (EBUS-TBNA) is minimally invasive technique used for diagnosis and/or staging of benign and malignant pulmonary and non-pulmonary disease. Prev...

    Authors: Nicola Bailey, Zoe Krisnadi, Raena Kaur, Siobhain Mulrennan, Martin Phillips and Neli Slavova-Azmanova

    Citation: BMC Pulmonary Medicine 2019 19:155

    Content type: Research article

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  15. Atypical manifestations, such as elevated serum immunoglobulin-G4 (IgG4) and extra-pulmonary IgG4 positive plasmacyte infiltration, have been described in patients with eosinophilic granulomatosis with polyang...

    Authors: Li Zhou, Fen Cao, Songqing Fan, Ping Chen, Shuizi Ding, Guiqian Liu and Ruoyun Ouyang

    Citation: BMC Pulmonary Medicine 2019 19:154

    Content type: Case report

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  16. Honeycombing on high-resolution computed tomography (HRCT) is a distinguishing feature of usual interstitial pneumonia and predictive of poor outcome in interstitial lung diseases (ILDs). Although fine crackle...

    Authors: Toshikazu Fukumitsu, Yasushi Obase, Yuji Ishimatsu, Shota Nakashima, Hiroshi Ishimoto, Noriho Sakamoto, Kosei Nishitsuji, Shunpei Shiwa, Tomoya Sakai, Sueharu Miyahara, Kazuto Ashizawa, Hiroshi Mukae and Ryo Kozu

    Citation: BMC Pulmonary Medicine 2019 19:153

    Content type: Research article

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  17. The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We investigated the incidence of adverse events and cure...

    Authors: Conor D. Tweed, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Lerato Mohapi, Michael E. Murphy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman and Stephen H. Gillespie

    Citation: BMC Pulmonary Medicine 2019 19:152

    Content type: Research article

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  18. Histoplasmosis is a mycosis caused by soil-based fungus Histoplasma capsulatum endemic in the USA, Latin America, Africa and South-East Asia. The disease is usually self-resolving, but exposure to a large inoculu...

    Authors: Krzysztof Specjalski, Karolina Kita, Krzysztof Kuziemski, Beata Tokarska, Lucyna Górska, Jolanta Szade, Alicja Siemińska, Marta Chełmińska and Ewa Jassem

    Citation: BMC Pulmonary Medicine 2019 19:150

    Content type: Case report

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  19. Lung cancer is a common comorbidity of idiopathic pulmonary fibrosis (IPF) and has poor outcomes. The incidence and clinical factors related to development of lung cancer in idiopathic pulmonary fibrosis (IPF)...

    Authors: Hongseok Yoo, Byeong-Ho Jeong, Myung Jin Chung, Kyung Soo Lee, O. Jung Kwon and Man Pyo Chung

    Citation: BMC Pulmonary Medicine 2019 19:149

    Content type: Research article

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  20. Oxygen toxicity is one potential side effect of hyperbaric oxygen therapy (HBOT). Previous small studies showed mild reductions in pulmonary functions reflecting reductions in small airway conductance after re...

    Authors: Amir Hadanny, Tal Zubari, Liat Tamir-Adler, Yair Bechor, Gregory Fishlev, Erez Lang, Nir Polak, Jacob Bergan, Mony Friedman and Shai Efrati

    Citation: BMC Pulmonary Medicine 2019 19:148

    Content type: Research article

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  21. Pneumonia is a significant public health problem globally. The early identification and management of the determinants of pneumonia demands clear evidence. But, there is a limited data on this issue in the cur...

    Authors: Sefinew Getaneh, Girma Alem, Maru Meseret, Yihun Miskir, Tilahun Tewabe, Gebeyaw Molla and Yihalem Abebe Belay

    Citation: BMC Pulmonary Medicine 2019 19:147

    Content type: Research article

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  22. Clinical studies demonstrate that ivacaftor (IVA) improves health-related quality of life (HRQoL) in patients aged ≥6 years with cystic fibrosis (CF). The real-world impact of IVA and standard of care (SOC) in...

    Authors: Scott C. Bell, Jochen G. Mainz, Gordon MacGregor, Susan Madge, Julie Macey, Moshe Fridman, Ellison D. Suthoff, Siva Narayanan and Nils Kinnman

    Citation: BMC Pulmonary Medicine 2019 19:146

    Content type: Research article

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  23. Aerosol administration is increasingly being used as a therapeutic intervention for mechanically ventilated preterm infants. However, the effects of inhalation therapy on retinopathy of prematurity (ROP) have ...

    Authors: Mei-Chin Yang, Hsiu-Feng Hsiao, Hsiu-Li Tseng, Ya-Wen Chiu and Yi-Hao Weng

    Citation: BMC Pulmonary Medicine 2019 19:145

    Content type: Research article

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  24. Asthma is a heterogeneous disease and understanding this heterogeneity will enable the realisation of precision medicine. We sought to compare the sputum and serum inflammatory profiles in moderate-to-severe a...

    Authors: Michael A. Ghebre, Pee Hwee Pang, Dhananjay Desai, Beverley Hargadon, Chris Newby, Joanne Woods, Laura Rapley, Suzanne E. Cohen, Athula Herath, Erol A. Gaillard, Richard D. May and Chris E. Brightling

    Citation: BMC Pulmonary Medicine 2019 19:144

    Content type: Research article

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  25. A minority of patients presenting with lower respiratory tract infection (LRTI) to their general practitioner (GP) have community-acquired pneumonia (CAP) and require antibiotic therapy. Identifying them is ch...

    Authors: Loïc Lhopitallier, Andreas Kronenberg, Jean-Yves Meuwly, Isabella Locatelli, Julie Dubois, Joachim Marti, Yolanda Mueller, Nicolas Senn, Valérie D’Acremont and Noémie Boillat-Blanco

    Citation: BMC Pulmonary Medicine 2019 19:143

    Content type: Study protocol

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  26. This study aims to investigate the effects of CCAAT/enhancer binding protein alpha (C/EBPα) overexpression on cell proliferation, apoptosis and surfactant protein-C(SP-C) in alveolar epithelial type II (AEC II...

    Authors: Hongyan Lu, Xiaoqing Chen, Yanmin Lu, Haitao Zhu, Wei Tang and Qiuxia Wang

    Citation: BMC Pulmonary Medicine 2019 19:142

    Content type: Research article

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  27. Epidemiologic characteristics of nontuberculous mycobacterial (NTM) disease remain largely unknown. The objective of this study was to evaluate incidence, prevalence, and mortality of NTM infection in a large ...

    Authors: Seon Cheol Park, Min Jin Kang, Chang Hoon Han, Sun Min Lee, Cheong Ju Kim, Jung Mo Lee and Young Ae Kang

    Citation: BMC Pulmonary Medicine 2019 19:140

    Content type: Research article

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  28. Caffeine therapy for apnea of prematurity reduces the incidence of bronchopulmonary dysplasia (BPD) in premature neonates. Several mechanisms, including improvement in pulmonary mechanics underly beneficial ef...

    Authors: Vikramaditya Dumpa, Lori Nielsen, Huamei Wang and Vasantha H. S. Kumar

    Citation: BMC Pulmonary Medicine 2019 19:138

    Content type: Research article

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  29. Th17 cells are believed to be important proinflammatory cells in the pathogenesis of chronic obstructive pulmonary disease (COPD). Recent evidence demonstrates that Th17 cells display substantial developmental...

    Authors: Weihan Xu, Ruimin Li and Yongchang Sun

    Citation: BMC Pulmonary Medicine 2019 19:137

    Content type: Research article

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  30. Chest computed tomography (CT) scans have a recognised role in investigating adults with severe asthma to exclude alternative diagnoses, but its role in children is less clear. The objective of this study was ...

    Authors: David Lo, Amit Maniyar, Sumit Gupta and Erol Gaillard

    Citation: BMC Pulmonary Medicine 2019 19:136

    Content type: Research article

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  31. Primary ciliary dyskinesia (PCD) is a rare genetic disorder. Although the genetic tests and new diagnostic algorithms have recently been recommended, clinical signs and electron microscope (EM) findings have h...

    Authors: Atsushi Inaba, Masanori Furuhata, Kozo Morimoto, Mahbubur Rahman, Osamu Takahashi, Minako Hijikata, Michael R. Knowles and Naoto Keicho

    Citation: BMC Pulmonary Medicine 2019 19:135

    Content type: Research article

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  32. To investigate the effect of asthma rehabilitation at high altitude (3100 m, HA) compared to low altitude (760 m, LA).

    Authors: Stéphanie Saxer, Simon R. Schneider, Paula Appenzeller, Patrick R. Bader, Mona Lichtblau, Michael Furian, Ulan Sheraliev, Bermet Estebesova, Berik Emilov, Talant Sooronbaev, Konrad E. Bloch and Silvia Ulrich

    Citation: BMC Pulmonary Medicine 2019 19:134

    Content type: Research article

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  33. Pulmonary capillary hemangiomatosis (PCH) is a progressive and refractory vascular disease in the lung. Pulmonary hypertension is frequently combined with PCH when capillary proliferation invades to nearby pul...

    Authors: Chang Dong Yeo, Deokjae Han, Jongmin Lee, Woo-Baek Chung, Jung Im Jung, Kyo-Young Lee, Tae-Jung Kim, Woori Jang, Myungshin Kim and Ji Young Kang

    Citation: BMC Pulmonary Medicine 2019 19:133

    Content type: Case report

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  34. Culturing of bronchoalveolar lavage (BAL) fluid is a commonly used method for pathogen detection in pneumonia. However, the sensitivity is low, especially in patients pre-treated with anti-infective agents. Th...

    Authors: Eva Tschiedel, Arkadius Goralski, Jörg Steinmann, Peter-Michael Rath, Margarete Olivier, Uwe Mellies, Tanja Kottmann and Florian Stehling

    Citation: BMC Pulmonary Medicine 2019 19:132

    Content type: Research article

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  35. Noninvasive ventilation (NIV) reduces the rate of endotracheal intubation (ETI) and overall mortality in severe acute exacerbation of COPD (AECOPD) with acute respiratory failure and is increasingly applied in...

    Authors: Alexandru T. Steriade, Shirin Johari, Nicoleta Sargarovschi, Daniela Necula, Cornelia E. Tudose, Diana Ionita, Miron A. Bogdan and Dragos Bumbacea

    Citation: BMC Pulmonary Medicine 2019 19:131

    Content type: Research article

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  36. The aim of this study was to analyze the relative frequency, clinical characteristics, disease onset and progression in f-IPF vs. sporadic IPF (s-IPF).

    Authors: Ekaterina Krauss, Godja Gehrken, Fotios Drakopanagiotakis, Silke Tello, Ruth C. Dartsch, Olga Maurer, Anita Windhorst, Daniel von der Beck, Matthias Griese, Werner Seeger and Andreas Guenther

    Citation: BMC Pulmonary Medicine 2019 19:130

    Content type: Research article

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  37. Tralokinumab is an anti–interleukin (IL)-13 monoclonal antibody investigated for the treatment of severe, uncontrolled asthma in two Phase III clinical trials, STRATOS 1 and 2. The STRATOS 1 biomarker analysis...

    Authors: Mattis Gottlow, David J. Svensson, Ilya Lipkovich, Monika Huhn, Karin Bowen, Peter Wessman and Gene Colice

    Citation: BMC Pulmonary Medicine 2019 19:129

    Content type: Technical advance

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  38. In people with and without Cystic Fibrosis (CF), does side lying during nebulisation change: the proportion of the dose loaded in the nebuliser that is deposited in the lungs; the uniformity of deposition thro...

    Authors: Ruth L. Dentice, Mark R. Elkins, Jordan Verschuer, Stefan Eberl, Genevieve Dwyer and Peter T. P. Bye

    Citation: BMC Pulmonary Medicine 2019 19:128

    Content type: Research article

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  39. In patients with chronic obstructive pulmonary disease, all efforts should be made to prevent exacerbations because each event modifies the trajectory of the disease. Treatment recommendations are mostly built...

    Authors: Laurie Pahus, Pierre-Régis Burgel, Nicolas Roche, Jean-Louis Paillasseur and Pascal Chanez

    Citation: BMC Pulmonary Medicine 2019 19:127

    Content type: Research article

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  40. The Nelson mortality results were presented in September 2018. Four other randomized control trials (RCTs) were also reported the latest mortality outcomes in 2018 and 2019. We therefore conducted a meta-analy...

    Authors: Kai-Lin Huang, Shih-Yuan Wang, Wan-Chen Lu, Ya-Hui Chang, Jian Su and Yen-Ta Lu

    Citation: BMC Pulmonary Medicine 2019 19:126

    Content type: Research article

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  41. Medical thoracoscopy is considered an overall safe procedure, whereas numbers of studies focus on complications of diagnostic thoracoscopy and talc poudrage pleurodesis. We conduct this study to evaluate the s...

    Authors: Yun-Yan Wan, Cong-Cong Zhai, Xin-Shan Lin, Zhou-Hong Yao, Qing-Hua Liu, Ling Zhu, De-Zhi Li, Xi-Li Li, Ning Wang and Dian-Jie Lin

    Citation: BMC Pulmonary Medicine 2019 19:125

    Content type: Research article

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  42. Pulmonary tuberculosis is a leading cause of morbidity and mortality in developing countries. Drug resistance, a huge problem in this contagious disease, is driven by point mutations in the Mycobacterium tubercul...

    Authors: David Patrick Kateete, Rogers Kamulegeya, Edgar Kigozi, Fred Ashaba Katabazi, Deus Lukoye, Sindani Ireneaus Sebit, Hergeye Abdi, Peter Arube, George William Kasule, Kenneth Musisi, Myalo Glen Dlamini, Derrick Khumalo and Moses L. Joloba

    Citation: BMC Pulmonary Medicine 2019 19:124

    Content type: Research article

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  43. In Latin America, there is scarce information about severe asthma (SA) according to the ERS/ATS 2014 criteria. This study aimed to compare the demographic, socio, clinical characteristics, treatment, and use o...

    Authors: Hugo Neffen, Felipe Moraes, Karynna Viana, Valentina Di Boscio, Gur Levy, Claudia Vieira, Gabriela Abreu and Claudia Soares

    Citation: BMC Pulmonary Medicine 2019 19:123

    Content type: Research article

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  44. Granulomatosis with polyangiitis (GPA) is characterised by the main violation of the upper and lower respiratory tract and kidney. GPA is considered a systemic vasculitis of medium-sized and small blood vessel...

    Authors: Lei Pan, Jun-Hong Yan, Fu-Quan Gao, Hong Li, Sha-Sha Han, Guo-Hong Cao, Chang-Jun Lv and Xiao-Zhi Wang

    Citation: BMC Pulmonary Medicine 2019 19:122

    Content type: Case report

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  45. The effectiveness of Incentive spirometry (IS) in patients undergoing video-assisted thoracic surgery (VATS) remains lacking. We conducted a population-based study to investigate the effectiveness of IS on pat...

    Authors: Chin-Jung Liu, Wen-Chen Tsai, Chia-Chen Chu, Chih-Hsin Muo and Wei-Sheng Chung

    Citation: BMC Pulmonary Medicine 2019 19:121

    Content type: Research article

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  46. Patients with interstitial lung disease (ILD) who show features related to autoimmunity without meeting criteria for a defined connective tissue disease are categorized as interstitial pneumonia with autoimmun...

    Authors: Jeong Uk Lim, Bo Mi Gil, Hye Seon Kang, Jongyeol Oh, Yong Hyun Kim and Soon Seog Kwon

    Citation: BMC Pulmonary Medicine 2019 19:120

    Content type: Research article

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