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  1. Yanghe Pingchuan decoction (YPD) has been used for asthma treatment for many years in China. We sought to understand the mechanism of YPD, and find more potential targets for YPD-based treatment of asthma.

    Authors: Lingyu Pan, Bangfu He, Chunxia Gong, Yehong Sun, Xianchun Duan, Yanquan Han, Jijun Chu and Yongzhong Wang
    Citation: BMC Pulmonary Medicine 2024 24:137
  2. Lung cancer (LC) is an important comorbidity of interstitial lung disease (ILD) and has a poor prognosis. The clinical characteristics and outcome of each ILD subtype in LC patients have not been sufficiently ...

    Authors: Soo Jin Han, Hyeon Hwa Kim, Dong-gon Hyun, Wonjun Ji, Chang-Min Choi, Jae Cheol Lee and Ho Cheol Kim
    Citation: BMC Pulmonary Medicine 2024 24:136
  3. Household contacts of tuberculosis (TB) patients are at a greater risk of infection and developing TB as well. Despite recommendations to actively screen such high-risk groups for TB, it is poorly implemented ...

    Authors: Habtamu Milkias Wolde, Betselot Zerihun, Waganeh Sinshaw, Delenasaw Yewhalaw and Gemeda Abebe
    Citation: BMC Pulmonary Medicine 2024 24:135
  4. Severe asthma is characterized by frequent exacerbations, altered lung function, and impaired quality of life. Tailored patient education allows for the improvement of both asthma management and quality of lif...

    Authors: Rodolphe Laurence, Julien Ancel, Maëva A. Devilliers, Sophie Carre, Sandra Dury, Valérian Dormoy, Gaëtan Deslée and Jeanne-Marie Perotin
    Citation: BMC Pulmonary Medicine 2024 24:134
  5. In epidemiological studies, the age at asthma onset is often defined by patients’ self-reported age at diagnosis. The reliability of this report might be questioned. Our objective was to evaluate the agreement...

    Authors: Elias Nurmi, Iida Vähätalo, Pinja Ilmarinen, Heidi Andersén, Leena E. Tuomisto, Anssi Sovijärvi, Helena Backman, Lauri Lehtimäki, Linnea Hedman, Arnulf Langhammer, Bright I. Nwaru, Päivi Piirilä and Hannu Kankaanranta
    Citation: BMC Pulmonary Medicine 2024 24:133
  6. This is a letter in response to an article by Ahmed et al., which concluded that in comparison to salbutamol, Fluticasone/salmeterol combination increases FEV1, FEV1% of predicted, and FEV1/FVC ratio, however it ...

    Authors: Divya Balan, Manish R Shetty and Manu K Mohan
    Citation: BMC Pulmonary Medicine 2024 24:132

    The original article was published in BMC Pulmonary Medicine 2023 23:381

  7. Bronchopulmonary dysplasia (BPD) is characterized by alveolar dysplasia, and evidence indicates that interferon regulatory factor 4 (IRF4) is involved in the pathogenesis of various inflammatory lung diseases. No...

    Authors: He Langyue, Zhu Ying, Jiang Jianfeng, Zhu Yue, Yao Huici and Lu Hongyan
    Citation: BMC Pulmonary Medicine 2024 24:130
  8. Previous observational research showed a potential link between physical activities such as walking and the risk of lung cancer. However, Mendelian randomization (MR) studies suggested there was no association...

    Authors: Fangjun Chen, Chutong Lin, Xing Gu, Yingze Ning, Huayu He and Guangliang Qiang
    Citation: BMC Pulmonary Medicine 2024 24:129
  9. With the increasing research on extracellular vesicles (EVs), EVs have received widespread attention as biodiagnostic markers and therapeutic agents for a variety of diseases. Stem cell-derived EVs have also b...

    Authors: Xuefeng Zhang, Zongyong Cheng, Menghao Zeng and Zhihui He
    Citation: BMC Pulmonary Medicine 2024 24:128
  10. The 2017 ATS/ERS technical standard for measuring the single-breath diffusing capacity (DLCO) proposed the “rapid-gas-analyzer” (RGA) or, equivalently, “total-breath” (TB) method for the determination of total...

    Authors: Rudolf A. Jörres, Christian Buess, Andreas Piecyk, Bruce Thompson, Sanja Stanojevic and Helgo Magnussen
    Citation: BMC Pulmonary Medicine 2024 24:127
  11. The long-term consequences of prematurity are often not sufficiently recognized. To address this gap, a prospective cohort study, which is a continuation of the multicenter Polish study PREMATURITAS, was condu...

    Authors: Katarzyna Walicka-Serzysko, Magdalena Postek, Urszula Borawska-Kowalczyk, Katarzyna Szamotulska, Piotr Kwaśniewicz, Krystyna Polak, Ewa Mierzejewska, Dorota Sands and Magdalena Rutkowska
    Citation: BMC Pulmonary Medicine 2024 24:126
  12. Data related to the characteristics, treatments and clinical outcomes of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) patients in China are limited, and sex differences are still a negl...

    Authors: Jiarui Zhang, Qun Yi, Chen Zhou, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Jianchu Zhang, Xianhua Li, Xiufang Xie, Pinhua Pan, Mengqiu Yi, Lina Cheng, Hui Zhou, Liang Liu, Adila Aili…
    Citation: BMC Pulmonary Medicine 2024 24:125
  13. While it is known that the overconsumption of ultra-processed foods (UPFs) is associated with a heightened risk of respiratory ailments, the specific effects of UPF intake on COPD remain unclear. This study wa...

    Authors: Zahra Salehi, Hanieh Malmir, Batoul Ghosn, Shokouh Onvani, Mohammad Emami Ardestani, Awat Feizi, Ahmad Esmaillzadeh and Leila Azadbakht
    Citation: BMC Pulmonary Medicine 2024 24:124
  14. Pembrolizumab is among the approved treatments for a variety of cancer types, including clear cell renal cell carcinoma (ccRCC). It has contributed to enhancing the prognosis of renal cell carcinoma. However, ...

    Authors: Oadi N. Shrateh, Yazan Abugharbieh, Yousef Abu Asbeh, Hani hour, Iyad Awad and Sami bannoura
    Citation: BMC Pulmonary Medicine 2024 24:123
  15. The existing respiratory fit test panels (RFTPs) are based on Bivariate and Principal Component Analysis (PCA) which utilise American and Chinese head and facial dimensions. As RFTPs based on local facial anth...

    Authors: Yin Cheng Lim, Shahrul Aiman Soelar, Ameerah Su’ad Abdul Shakor¹, Nadia Mohamad, Muhammad Alfatih Pahrol, Rohaida Ismail, Mahmoud Danaee and Rafiza Shaharudin
    Citation: BMC Pulmonary Medicine 2024 24:122
  16. Erlotinib is a first-generation, tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR-TKI) used for the treatment patients with NSCLC. Erlotinib is considered as a safe and effective treatme...

    Authors: Xin Yan, Jingxian Kong, Jiacheng Wang, Caixia Wang and Hongchang Shen
    Citation: BMC Pulmonary Medicine 2024 24:121
  17. A significant reduction in regional cerebral oxygen saturation (rSO2) is commonly observed during one-lung ventilation (OLV), while positive end-expiratory pressure (PEEP) can improve oxygenation. We compared the...

    Authors: Liying Zhao, Shuang Lv, Qian Xiao, Yuan Zhang, Wenbo Yi, Yu Bai, Kangping Lu, Kevin C. Bermea, Jessica Semel, Xiaomei Yang and Jianbo Wu
    Citation: BMC Pulmonary Medicine 2024 24:120
  18. Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide among people over 40 years of age, and erythrocytosis is one of the major complications associated with increased mort...

    Authors: Amon Banturaki, Dalton Kambale Munyambalu, Dickson Kajoba, Verah Bella Onchoke, Alina Peris, Prosper Ryamugwiza, Jacinto Amandua and Kingsley Akaba
    Citation: BMC Pulmonary Medicine 2024 24:119
  19. This study assessed hospitalisation frequency and related clinical outcomes among adult Aboriginal Australians with bronchiectasis over a ten-year study period.

    Authors: Timothy Howarth, Claire Gibbs, Subash S. Heraganahally and Asanga Abeyaratne
    Citation: BMC Pulmonary Medicine 2024 24:118
  20. Little attention has been paid to the pathophysiological changes in the natural history of chronic obstructive pulmonary disease (COPD). The destructions of the small airways were visualized on thoracic micro-...

    Authors: Li Li, Ying Gong, Dongni Hou, Yijun Song, Jing Bi, Miao Li, Junjie Han, Yuanlin Song and Jun She
    Citation: BMC Pulmonary Medicine 2024 24:116
  21. IgG4-related disease is a systemic fibroinflammatory disease that is mainly seen in older men, and involves multiple organs, such as the pancreas and lungs. However, 75% of patients with IgG4-related lung dise...

    Authors: Atsushi Torii, Kahori Oshima, Akari Iwakoshi and Masahide Oki
    Citation: BMC Pulmonary Medicine 2024 24:115
  22. Early diagnosing Chronic Obstructive Pulmonary Disease (COPD) is relatively difficult. Therefore, the concepts of preserved ratio impaired spirometry (PRISm) and small airway disease (SAD) were proposed to ach...

    Authors: Le Sang, Xia Gong, Yunlei Huang and Jian Sun
    Citation: BMC Pulmonary Medicine 2024 24:114
  23. Chronic obstructive pulmonary disease (COPD) is a common disease associated with premature death. Tobacco exposure is the main risk factor, but lower socioeconomic status, early life insults, and occupational ...

    Authors: Nina Brünés, Mette Bendtz Lindstroem, Charlotte Suppli Ulrik, Ove Andersen, Marianne Lisby, Nina Skavlan Godtfredsen, Tina Leth Hansen, Charlotta Pisinger, Vibeke Graven, Kristoffer Marsaa and Laura Hohwü Thomsen
    Citation: BMC Pulmonary Medicine 2024 24:113
  24. The prevalence of obstructive sleep apnea (OSA) was found to be higher in individuals following COVID-19 infection. However, the intricate mechanisms that underscore this concomitance remain partially elucidat...

    Authors: Hong Luo, Jisong Yan, Rui Gong, Dingyu Zhang, Xia Zhou and Xianguang Wang
    Citation: BMC Pulmonary Medicine 2024 24:112
  25. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) combined with respiratory failure (RF) is a chronic respiratory disease that seriously endangers human health. This study aimed to specifica...

    Authors: Ruoqing Zhou and Dianzhu Pan
    Citation: BMC Pulmonary Medicine 2024 24:111
  26. Both sepsis and acute respiratory distress syndrome (ARDS) are common severe diseases in the intensive care unit (ICU). There is no large-scale multicenter study to clarify the attributable mortality of ARDS a...

    Authors: Dong-Hui Wang, Hui-Miao Jia, Xi Zheng, Xiu-Ming Xi, Yue Zheng and Wen-Xiong Li
    Citation: BMC Pulmonary Medicine 2024 24:110
  27. High-altitude pulmonary edema (HAPE) refers to the onset of breathlessness, cough, and fever at rest after arriving at high altitudes. It is a life-threatening illness caused by rapid ascent to high altitudes....

    Authors: Dava Tenzing, Pianduo Suolang, Deji Gesang, Duoji Suolang, Gaozhan Duan, Wangmu Ciren, Yihui Wang and Tongtian Ni
    Citation: BMC Pulmonary Medicine 2024 24:109
  28. Safely implementing transbronchial lung cryobiopsy (TBLC) in patients with interstitial lung disease (ILD) requires accurate navigation. Traditional fluoroscopy falls short in reducing the risk of post-procedu...

    Authors: Shiyao Wang, Jinmi Yang, Sa Luo, Jing Geng, Yanhong Ren, Ling Zhao, Min Liu, Dan Wang, Ying Li, Zheng Tian, Wei Liu, Guowu Zhou and Huaping Dai
    Citation: BMC Pulmonary Medicine 2024 24:108
  29. Mycoplasma pneumoniae infections have increased in China recently, causing some evidence of familial clustering. The purpose of this study was to compare the clinical features of parents and children in cases of...

    Authors: Xu Liu, Qingfeng Zhang, Hao Chen, Yueying Hao, Jingyi Zhang, Shiqian Zha, Beini Zhou, Yaohua Yi, Rui Xiao and Ke Hu
    Citation: BMC Pulmonary Medicine 2024 24:107
  30. The main focus on the characteristics of malignant lung tumours has been the size, position within the lobe, and infiltration into neighbouring structures. The aim of this study was to investigate the distribu...

    Authors: Yngvar Nilssen, Odd Terje Brustugun, Lars Fjellbirkeland, Åslaug Helland, Bjørn Møller, Sissel Gyrid Freim Wahl and Steinar Solberg
    Citation: BMC Pulmonary Medicine 2024 24:106
  31. While the prevalence of severe cases and mortality rate of coronavirus disease 2019 (COVID-19) appear to be reducing, the clinical characteristics and severity of hospitalized patients with asthma and COVID-19...

    Authors: Akinari Tsukada, Junko Terada-Hirashima, Jin Takasaki, Hiroshi Nokihara, Shinyu Izumi, Masayuki Hojo and Haruhito Sugiyama
    Citation: BMC Pulmonary Medicine 2024 24:105
  32. Ventilator-associated pneumonia (VAP) is one of the leading causes of mortality in patients with critical care illness. Since obesity is highly prevalent, we wanted to study its impact on the outcomes of patie...

    Authors: Mohamad El Labban, Michella Abi Zeid Daou, Hiba Smaily, Abbas Hammoud, Ghandi Hassan, Syed Khan and Imad Bou Akl
    Citation: BMC Pulmonary Medicine 2024 24:104
  33. Randomized controlled trials described beneficial effects of inhaled triple therapy (LABA/LAMA/ICS) in patients with chronic obstructive pulmonary disease (COPD) and high risk of exacerbations. We studied whet...

    Authors: Jennifer A. Zader, Rudolf A. Jörres, Imke Mayer, Peter Alter, Robert Bals, Henrik Watz, Pontus Mertsch, Klaus F. Rabe, Felix Herth, Franziska C. Trudzinski, Tobias Welte, Hans-Ulrich Kauczor, Jürgen Behr, Julia Walter, Claus F. Vogelmeier and Kathrin Kahnert
    Citation: BMC Pulmonary Medicine 2024 24:103
  34. To investigate pulmonary thromboembolism (PE) in acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) patients in plateau regions, we performed a prospective cohort study to evaluate the preva...

    Authors: Chenlu Yang, Yajun Tuo, Xuefeng Shi, Jie Duo, Xin Liu, Fang Zhang and Xiaokai Feng
    Citation: BMC Pulmonary Medicine 2024 24:102
  35. Pulmonary arterial hypertension is a serious medical condition. However, the condition is often misdiagnosed or a rather long delay occurs from symptom onset to diagnosis, associated with decreased 5-year surv...

    Authors: Shun Imai, Seiichiro Sakao, Jun Nagata, Akira Naito, Ayumi Sekine, Toshihiko Sugiura, Ayako Shigeta, Akira Nishiyama, Hajime Yokota, Norihiro Shimizu, Takeshi Sugawara, Toshiaki Nomi, Seiwa Honda, Keisuke Ogaki, Nobuhiro Tanabe, Takayuki Baba…
    Citation: BMC Pulmonary Medicine 2024 24:101
  36. Tuberculosis (TB) is a significant global health concern, given its high rates of morbidity and mortality. The diagnosis using urine lipoarabinomannan (LAM) primarily benefits HIV co-infected TB patients with ...

    Authors: Yan Li, Zhiwei Ru, Hongxia Wei, Ming Wu, Guihua Xie, Jianrong Lou, Xiang Yang and Xilin Zhang
    Citation: BMC Pulmonary Medicine 2024 24:100
  37. The most common and potentially fatal side effect of thoracic radiation therapy is radiation pneumonitis (RP). Due to the lack of effective treatments, predicting radiation pneumonitis is crucial. This study a...

    Authors: Yawen Zha, Jingjing Zhang, Xinyu Yan, Chen Yang, Lei Wen and Minying Li
    Citation: BMC Pulmonary Medicine 2024 24:99
  38. The concept of eosinophilic bronchiectasis has received clinical attention recently, but the association between blood eosinophil count (BEC) and hospital characteristics has rarely been reported yet. We aim t...

    Authors: Chengcheng Lei, Zhimin Zeng, Fengjia Chen, Yubiao Guo and Yangli Liu
    Citation: BMC Pulmonary Medicine 2024 24:98
  39. While cutaneous melanomas are well-documented, primary melanoma of the lung (PMML), particularly with endobronchial origin, remains rare and poorly characterized. This case report addresses gaps in understandi...

    Authors: Emanuela Barisione, Andrea Boutros, Marco Mora, Francesco Spagnolo, Enrica Teresa Tanda, Carlo Genova and Elena Tagliabue
    Citation: BMC Pulmonary Medicine 2024 24:97
  40. Advanced lung adenocarcinoma patients often develop resistance to EGFR tyrosine kinase inhibitors (EGFR-TKIs), leaving uncertainties regarding subsequent treatment strategies. Although personalized therapy tar...

    Authors: Kan Jiang, Lin Wu, Xinlong Zheng, Yiquan Xu, Qian Miao, Xiaobin Zheng, Longfeng Zhang, Cheng Huang and Gen Lin
    Citation: BMC Pulmonary Medicine 2024 24:96
  41. Asthma is a common respiratory disease. In asthma, the small airways have more intensive inflammation and prominent airway remodelling, compared to the central airways. We aimed to investigate the predictive v...

    Authors: Lulu Zhang, Zhou Fu, Hua Deng, Qin Xie and Wenjie Wu
    Citation: BMC Pulmonary Medicine 2024 24:94
  42. To evaluate the efficacy of high-flow nasal cannula oxygenation (HFNC) versus non-invasive ventilation (NIV) in pediatric patients post-congenital heart surgery (CHS) through a meta-analysis.

    Authors: Si-Jia Zhou, Xiu-Hua Chen, Ying-Ying Liu, Qiang Chen, Yi-Rong Zheng and Qi-Liang Zhang
    Citation: BMC Pulmonary Medicine 2024 24:92
  43. Alpha1-antitrypsin (AAT) is a serine protease inhibitor that serves as a counterbalance to the activity of elastases, e.g., neutrophil elastase in lung tissue. AAT deficiency (AATD) is a rare disorder usually ...

    Authors: Dilek Karadoğan, Ünal Şahin, Bettina Dreger, Laura Grandoso and Lourdes Osaba
    Citation: BMC Pulmonary Medicine 2024 24:91
  44. The data on bosentan were lacking for the treatment of exercise-induced elevation of pulmonary artery pressure (eePAP) or less severe PH in COPD. This study was conducted to investigate long-term efficacy and ...

    Authors: Takeru Kashiwada, Yosuke Tanaka, Toru Tanaka, Tetsuya Okano, Yoshinobu Saito, Masahiro Seike, Mitsunori Hino, Hiroshi Kimura and Akihiko Gemma
    Citation: BMC Pulmonary Medicine 2024 24:90
  45. Several studies have indicated that intrapleural infusion of bevacizumab is an effective treatment for non-small cell lung cancer (NSCLC) with malignant pleural effusion (MPE). However, the impact of bevacizum...

    Authors: Hao Zeng, Yuanyuan Zhang, Sihan Tan, Qin Huang, Xin Pu, Panwen Tian and Yalun Li
    Citation: BMC Pulmonary Medicine 2024 24:89
  46. Incentive spirometry (IS) as a routine respiratory therapy during the perioperative period has been widely used in clinical practice. However, the impact of IS on patients with perioperative lung cancer remain...

    Authors: Yan Liang, Shaolin Chen, Jiamei Song, Ting Deng, Jinfen Yang, Yangyang Long, Lorna Kwai Ping Suen and Xu Luo
    Citation: BMC Pulmonary Medicine 2024 24:88

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