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  1. Asthma patients with obesity often have a high disease burden, despite the use of high-dose inhaled corticosteroids (ICS). In contrast to asthmatics with normal weight, the efficacy of ICS in patients with obe...

    Authors: Jan A. Witte, Gert-Jan Braunstahl, Wouter J. B. Blox, Susan C. van ’t Westeinde, Johannes C. C. M. in ’t Veen, Jasper H. Kappen and Elisabeth F. C. van Rossum
    Citation: BMC Pulmonary Medicine 2022 22:53
    Content type: Study protocol Published on:

  2. Understanding heterogeneity seen in patients with COVIDARDS and comparing to non-COVIDARDS may inform tailored treatments.

    Authors: Daniel Jafari, Amir Gandomi, Alex Makhnevich, Michael Qiu, Daniel M. Rolston, Eric P. Gottesman, Adey Tsegaye, Paul H. Mayo, Molly E. Stewart, Meng Zhang and Negin Hajizadeh
    Citation: BMC Pulmonary Medicine 2022 22:51
    Content type: Research article Published on:

  3. Authors: Pierluigi Donatelli, Fabiana Trentacosti, Maria Rosaria Pellegrino, Roberto Tonelli, Giulia Bruzzi, Alessandro Andreani, Gaia Francesca Cappiello, Dario Andrisani, Filippo Gozzi, Cristina Mussini, Stefano Busani, Gilda Valentina Cavaliere, Massimo Girardis, Elisabetta Bertellini, Enrico Clini and Alessandro Marchioni
    Citation: BMC Pulmonary Medicine 2022 22:50
    Content type: Correction Published on:

    The original article was published in BMC Pulmonary Medicine 2021 21:307

  4. Recent studies support the diagnostic role of bronchoalveolar lavage lymphocytosis (BALL) in patients with suspected hypersensitivity pneumonitis (HP). Our study aim was to determine the spectrum of BALL findi...

    Authors: Meghan Hill, Tananchai Petnak and Teng Moua
    Citation: BMC Pulmonary Medicine 2022 22:49
    Content type: Research Published on:

  5. A systematic examination of low-dose CT (LDCT) scan, beside lung nodules, may disclose the presence of undiagnosed diseases, improving the efficacy and the cost/efficacy of these programs. The study was aimed ...

    Authors: Panaiotis Finamore, Luigi Tanese, Filippo Longo, Domenico De Stefano, Claudio Pedone, Laura Angelici, Nera Agabiti, Silvia Cascini, Marina Davoli, Bruno Beomonte Zobel, Raffaele Antonelli Incalzi and Pierfilippo Crucitti
    Citation: BMC Pulmonary Medicine 2022 22:48
    Content type: Research article Published on:

  6. The need for invasive mechanical ventilation (IMV) is linked to significant morbidity and mortality in patients with influenza-related pneumonia (Flu-p). We aimed to develop an assessment tool to predict IMV a...

    Authors: Liang Chen, Xiudi Han, YanLi Li, Chunxiao Zhang and Xiqian Xing
    Citation: BMC Pulmonary Medicine 2022 22:47
    Content type: Research Published on:

  7. The usefulness and safety of transbronchial lung cryobiopsy (TBLC) for reassessment of diffuse parenchymal lung disease (DPLD) with progression is still unknown. Our purpose was to clarify the usefulness and s...

    Authors: Yozo Sato, Tomohisa Baba, Hideya Kitamura, Takashi Niwa, Shigeru Komatsu, Eri Hagiwara, Tae Iwasawa, Koji Okudela, Tamiko Takemura and Takashi Ogura
    Citation: BMC Pulmonary Medicine 2022 22:46
    Content type: Research Published on:

  8. The Asian Working Group for Sarcopenia 2019 (AWGS 2019) is the gold standard diagnostic criteria for sarcopenia in Asian populations. The calf circumference (CalF), the strength, assistance in walking, rising ...

    Authors: Masatoshi Hanada, Noriho Sakamoto, Hiroshi Ishimoto, Takashi Kido, Takuto Miyamura, Masato Oikawa, Hiroki Nagura, Rina Takeuchi, Yurika Kawazoe, Shuntaro Sato, S. Ahmed Hassan, Yuji Ishimatsu, Hideaki Takahata, Hiroshi Mukae and Ryo Kozu
    Citation: BMC Pulmonary Medicine 2022 22:45
    Content type: Research Published on:

  9. Thoracic multidetector computed tomography (MDCT) is essential for the detection of interstitial lung disease (ILD) in patients with systemic sclerosis (SSc). Thoracic MDCT assessment can reveal the presence o...

    Authors: Arthur Renaud, Raphael Pautre, Olivier Morla, Aurélie Achille, Cécile Durant, Olivier Espitia, Eric Frampas and Christian Agard
    Citation: BMC Pulmonary Medicine 2022 22:44
    Content type: Research Published on:

  10. Sarcoidosis incidence peaks in females around the fifth decade of life, which coincides with menopause, suggesting hormonal factors play a role in disease development. We investigated whether longer exposure t...

    Authors: Marina Dehara, Michael C. Sachs, Susanna Kullberg, Johan Grunewald, Anders Blomberg and Elizabeth V. Arkema
    Citation: BMC Pulmonary Medicine 2022 22:43
    Content type: Research Published on:

  12. Respiratory medicine (RM) and palliative care (PC) physicians’ management of chronic breathlessness in advanced chronic obstructive pulmonary disease (COPD), fibrotic interstitial lung disease (fILD) and lung ...

    Authors: Małgorzata Krajnik, Nilay Hepgul, Andrew Wilcock, Ewa Jassem, Tomasz Bandurski, Silvia Tanzi, Steffen T. Simon, Irene J. Higginson and Caroline J. Jolley
    Citation: BMC Pulmonary Medicine 2022 22:41
    Content type: Research Published on:

  13. The reported experience of surgical treatment for chronic pulmonary aspergillosis (CPA) mainly focused on simple aspergilloma (SA), few about other types of CPA. The present study aims to evaluate the outcomes...

    Authors: ChangMing Shen, GaoFeng Qiao, Cheng Wang, Feng Jin and YunZeng Zhang
    Citation: BMC Pulmonary Medicine 2022 22:40
    Content type: Research Published on:

  15. The coordination between different levels of care is essential for the management of obstructive sleep apnea (OSA). The objective of this multicenter project was to develop a screening model for OSA in the pri...

    Authors: Patricia Peñacoba, Maria Antònia Llauger, Ana María Fortuna, Xavier Flor, Gabriel Sampol, Anna Maria Pedro-Pijoan, Núria Grau, Carme Santiveri, Joan Juvanteny, José Ignacio Aoiz, Joan Bayó, Patricia Lloberes and Mercè Mayos
    Citation: BMC Pulmonary Medicine 2022 22:38
    Content type: Research article Published on:

  16. Prostaglandin E1 (PGE1) has been reported to maintain adequate oxygenation among patients under 60% FiO2 one-lung ventilation (OLV). This research aimed to explore whether PGE1 is safe in pulmonary shunt and oxyg...

    Authors: Pengyi Li, Lianbing Gu, Jing Tan, Zhenghuan Song, Qingming Bian, Dian Jiao, Zeping Xu and Lijun Wang
    Citation: BMC Pulmonary Medicine 2022 22:37
    Content type: Research Published on:

  19. Prediction of inpatients with community-acquired pneumonia (CAP) at high risk for severe adverse events (SAEs) requiring higher-intensity treatment is critical. However, evidence regarding prediction rules app...

    Authors: Toshihiro Sakakibara, Yuichiro Shindo, Daisuke Kobayashi, Masahiro Sano, Junya Okumura, Yasushi Murakami, Kunihiko Takahashi, Shigeyuki Matsui, Tetsuya Yagi, Hideo Saka and Yoshinori Hasegawa
    Citation: BMC Pulmonary Medicine 2022 22:34
    Content type: Research Published on:

  20. Asthma–chronic obstructive pulmonary disease (COPD) overlap (ACO) patients experience exacerbations more frequently than those with asthma or COPD alone. Since low diffusing capacity of the lung for carbon mon...

    Authors: Hiroaki Ogata, Katsuyuki Katahira, Aimi Enokizu-Ogawa, Yujiro Jingushi, Akiko Ishimatsu, Kazuhito Taguchi, Hiroko Nogami, Hiroshi Aso, Atsushi Moriwaki and Makoto Yoshida
    Citation: BMC Pulmonary Medicine 2022 22:22
    Content type: Research Published on:

  21. Social and hospital environmental factors that may be associated with hospital-acquired pneumonia (HAP) have not been evaluated. Comprehensive risk assessment for the incidence of HAP including sociodemographi...

    Authors: Bo-Guen Kim, Minwoong Kang, Jihyun Lim, Jin Lee, Danbee Kang, Minjung Kim, Jinhee Kim, Hyejeong Park, Kyung Hoon Min, Juhee Cho and Kyeongman Jeon
    Citation: BMC Pulmonary Medicine 2022 22:21
    Content type: Research Published on:

  22. No studies investigated the whole effect of modifiable lifestyle factors on OSA risk. This study aimed to examine the individual and combined effects of lifestyle factors on OSA risk among Chinese adults.

    Authors: Xueru Duan, Jun Huang, Murui Zheng, Wenjing Zhao, Lixian Lao, Haiyi Li, Zhiwei Wang, Jiahai Lu, Weiqing Chen, Hai Deng and Xudong Liu
    Citation: BMC Pulmonary Medicine 2022 22:33
    Content type: Research Published on:

  23. Advanced lung adenocarcinoma (LAC) is one of the most lethal malignancies worldwide. The aim of this study was to evaluate the global survival in a real-life cohort of patients with LAC harboring driver geneti...

    Authors: Panagiotis Paliogiannis, Maria Colombino, Maria Cristina Sini, Antonella Manca, Milena Casula, Grazia Palomba, Marina Pisano, Valentina Doneddu, Angelo Zinellu, Davide Santeufemia, Giovanni Sotgiu, Antonio Cossu and Giuseppe Palmieri
    Citation: BMC Pulmonary Medicine 2022 22:32
    Content type: Research Published on:

  24. A balloon occlusion technique is suggested for use in cryobiopsy for interstitial lung diseases because of the bleeding risk. However, it may interfere with selection of the involved bronchus for peripheral pu...

    Authors: Toshiyuki Nakai, Tetsuya Watanabe, Yuto Kaimi, Koichi Ogawa, Yoshiya Matsumoto, Kenji Sawa, Atsuko Okamoto, Kanako Sato, Kazuhisa Asai, Yuji Matsumoto, Masahiko Ohsawa and Tomoya Kawaguchi
    Citation: BMC Pulmonary Medicine 2022 22:20
    Content type: Research Published on:

  25. The anti-fibrotic medications nintedanib and pirfenidone were approved in the United States for use in patients with idiopathic pulmonary fibrosis several years ago. While there is a growing body of evidence s...

    Authors: Timothy M. Dempsey, Viengneesee Thao, James P. Moriarty, Bijan J. Borah and Andrew H. Limper
    Citation: BMC Pulmonary Medicine 2022 22:18
    Content type: Research Published on:

  26. The purpose was to clarify the characteristics of interstitial lung disease (ILD) in immune-mediated necrotizing myopathy (IMNM) patients with anti-signal recognition particle (SRP) antibodies.

    Authors: Yongpeng Ge, Hanbo Yang, Xinyue Xiao, Lin Liang, Xin Lu and Guochun Wang
    Citation: BMC Pulmonary Medicine 2022 22:14
    Content type: Research Published on:

  27. For decades, concurrent chemo-radiotherapy with cisplatin-based regimen has been a standard therapy for locally advanced stage III non-small-cell lung cancer (NSCLC). We conducted individual-participant-data (...

    Authors: Yuri Taniguchi, Hiroaki Okamoto, Tsuneo Shimokawa, Tomonari Sasaki, Takashi Seto, Seiji Niho, Yuichiro Ohe and Yusuke Saigusa
    Citation: BMC Pulmonary Medicine 2022 22:31
    Content type: Research Published on:

  29. Asthma is a heterogeneous disease and different phenotypes based on clinical parameters have been identified. However, the molecular subgroups of asthma defined by gene expression profiles of induced sputum ha...

    Authors: Min Li, Wenye Zhu, Ummair Saeed, Shibo Sun, Yan Fang, Chu Wang and Zhuang Luo
    Citation: BMC Pulmonary Medicine 2022 22:29
    Content type: Research Published on:

  31. Never smokers in Asia have a higher incidence of lung cancer than in Europe and North America. We aimed to assess the cost-effectiveness of lung cancer screening with low-dose computed tomography (LDCT) for ne...

    Authors: Akiko Kowada
    Citation: BMC Pulmonary Medicine 2022 22:19
    Content type: Research article Published on:

  32. Pneumocystis jirovecii pneumonia (PCP) with acute respiratory failure can result in development of pneumothorax during treatment. This study aimed to identify the incidence and related factors of pneumothorax in ...

    Authors: Ji Soo Choi, Se Hyun Kwak, Min Chul Kim, Chang Hwan Seol, Sung Ryeol Kim, Byung Hoon Park, Eun Hye Lee, Seung Hyun Yong, Ah Young Leem, Song Yee Kim, Sang Hoon Lee, Kyungsoo Chung, Eun Young Kim, Ji Ye Jung, Young Ae Kang, Moo Suk Park…
    Citation: BMC Pulmonary Medicine 2022 22:7
    Content type: Research Published on:

  33. The management of non-small cell lung cancer (NSCLC) has become increasingly complex due to the evolution of personalized medicine approaches. Such approaches are characterized by the necessity of adequate tum...

    Authors: Carlo Genova, Elena Tagliabue, Marco Mora, Teresita Aloè, Mariella Dono, Sandra Salvi, Lodovica Zullo and Emanuela Barisione
    Citation: BMC Pulmonary Medicine 2022 22:5
    Content type: Case report Published on:

  34. Resistance to gefitinib remains a major obstacle for the successful treatment of non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations. In this paper, we studied the precise...

    Authors: Daping Fan, Yue Yang and Wei Zhang
    Citation: BMC Pulmonary Medicine 2022 22:27
    Content type: Research Published on:

  35. Lung infection is a common cause of sepsis, and patients with sepsis and lung infection are more ill and have a higher mortality rate than sepsis patients without lung infection. We constructed a nomogram pred...

    Authors: Yinlong Ren, Luming Zhang, Fengshuo Xu, Didi Han, Shuai Zheng, Feng Zhang, Longzhu Li, Zichen Wang, Jun Lyu and Haiyan Yin
    Citation: BMC Pulmonary Medicine 2022 22:17
    Content type: Research Published on:

  36. Silicosis is a systemic disease characterized by persistent inflammation and incurable pulmonary fibrosis. Although great effort has been made to understand the pathogenesis of the disease, molecular mechanism...

    Authors: Cunxiang Bo, Juan Zhang, Linlin Sai, Zhongjun Du, Gongchang Yu, Chao Li, Ming Li, Cheng Peng, Qiang Jia and Hua Shao
    Citation: BMC Pulmonary Medicine 2022 22:13
    Content type: Research Published on:

  37. To differentiate nontuberculous mycobacteria (NTM) pulmonary diseases from pulmonary tuberculosis (PTB) by analyzing the CT radiomics features of their cavity.

    Authors: Qinghu Yan, Wuzhang Wang, Wenlong Zhao, Liping Zuo, Dongdong Wang, Xiangfei Chai and Jia Cui
    Citation: BMC Pulmonary Medicine 2022 22:4
    Content type: Research Published on:

  38. Incidental and screening-identified lung nodules are common, and a bronchoscopic evaluation is frequently nondiagnostic. The Percepta Genomic Sequencing Classifier (GSC) is a genomic classifier developed in cu...

    Authors: Sonali Sethi, Scott Oh, Alexander Chen, Christina Bellinger, Lori Lofaro, Marla Johnson, Jing Huang, Sangeeta Maruti Bhorade, William Bulman and Giulia C. Kennedy
    Citation: BMC Pulmonary Medicine 2022 22:26
    Content type: Research Published on:

  40. Various complications may arise from prolonged mechanical ventilation, but the risk of tracheal stenosis occurring late after translaryngeal intubation or tracheostomy is less common. This study aimed to deter...

    Authors: Alessandro Ghiani, Konstantinos Tsitouras, Joanna Paderewska, Dieter Munker, Swenja Walcher, Claus Neurohr and Nikolaus Kneidinger
    Citation: BMC Pulmonary Medicine 2022 22:24
    Content type: Research Published on:

  42. As one of the basic treatments performed in the intensive care unit, mechanical ventilation can cause ventilator-induced acute lung injury (VILI). The typical features of VILI are an uncontrolled inflammatory ...

    Authors: Leilei Zhou, Chunju Xue, Zongyu Chen, Wenqing Jiang, Shuang He and Xianming Zhang
    Citation: BMC Pulmonary Medicine 2022 22:9
    Content type: Research Published on:

  43. Mortality in severe COVID-19 pneumonia is associated with thrombo-inflammation. Corticosteroids are given to attenuate the inflammation, but they are associated with thrombosis. The aims of this study were to ...

    Authors: Ronaldo C. Go, Themba Nyirenda, Maryam Bojarian, Davood K. Hosseini, Mehek Rahim, Kevin Kim and Keith M. Rose
    Citation: BMC Pulmonary Medicine 2022 22:6
    Content type: Research Published on:

  44. The spirometer is an important element in lung function examinations, and its accuracy is directly related to the accuracy of the results of these examinations and to the diagnosis and treatment of diseases. O...

    Authors: Zhongping Wu, Ruibo Huang, Liping Zhong, Yi Gao and Jinping Zheng
    Citation: BMC Pulmonary Medicine 2022 22:23
    Content type: Research Published on:

  45. With the rapid advances of genetic and genomic technologies, the pathophysiological mechanisms of idiopathic pulmonary fibrosis (IPF) were gradually becoming clear, however, the prognosis of IPF was still poor...

    Authors: Yaowu He, Yu Shang, Yupeng Li, Menghan Wang, Dongping Yu, Yi Yang, Shangwei Ning and Hong Chen
    Citation: BMC Pulmonary Medicine 2022 22:15
    Content type: Research Published on:

  46. Chronic obstructive pulmonary disease (COPD) is a leading cause of global mortality. In high-income settings, the presence of cardiovascular disease among people with COPD increases mortality and complicates l...

    Authors: Rebecca F. Gilbert, Cody Cichowitz, Prossy Bibangambah, June-Ho Kim, Linda C. Hemphill, Isabelle T. Yang, Ruth N. Sentongo, Bernard Kakuhikire, David C. Christiani, Alexander C. Tsai, Samson Okello, Mark J. Siedner and Crystal M. North
    Citation: BMC Pulmonary Medicine 2022 22:12
    Content type: Research Published on:

  47. Accelerated nodulosis (ARN) is a rare variant of rheumatoid nodules (RNs) that is characterized by a rapid onset or the worsening of RNs. It generally develops at the fingers in patients with rheumatoid arthri...

    Authors: Akitake Suzuki, Shigeki Morita, Miho Ohshima, Nobuyoshi Minemura, Takeshi Suzuki, Masanobu Yoshida, Rikuo Machinami, Shuji Sakai and Chikao Torikata
    Citation: BMC Pulmonary Medicine 2022 22:10
    Content type: Case report Published on:

  48. “Overlap syndrome” refers to obstructive sleep apnea (OSA) combined with chronic obstructive pulmonary disease (COPD), and has poorer outcomes than either condition alone. We aimed to evaluate the prevalence a...

    Authors: Pan Zhang, Bi Chen, Heqing Lou, Yanan Zhu, Peipei Chen, Zongmei Dong, Xuan Zhu, Ting Li and Peian Lou
    Citation: BMC Pulmonary Medicine 2022 22:16
    Content type: Research Published on:

  49. Pulmonary blastoma (PB) comprises a rare heterogeneous group of lung tumours typically containing immature epithelial and mesenchymal structures that imitate the embryonic lung tissue and extremely rarely occu...

    Authors: Michał P. Budzik, Grzegorz Panek, Małgorzata Bińkowska, Beata Osuch, Ewa Borkowska and Anna M. Badowska-Kozakiewicz
    Citation: BMC Pulmonary Medicine 2022 22:8
    Content type: Case report Published on:

  50. Asthma exacerbation threatens patient's life. Several genetic studies have been conducted to determine the risk factors for asthma exacerbation, but this information is still lacking. We aimed to determine whe...

    Authors: Min-Hye Kim, Hun Soo Chang, Jong-Uk Lee, Ji-Su Shim, Jong-Sook Park, Young-Joo Cho and Choon-Sik Park
    Citation: BMC Pulmonary Medicine 2022 22:3
    Content type: Research Published on:
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