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  1. Content type: Research article

    Respiratory tract deposition of airborne particles is a key link to understand their health impact. Experimental data are limited for vulnerable groups such as individuals with respiratory diseases. The aim of...

    Authors: Jonas K F Jakobsson, H Laura Aaltonen, Hanna Nicklasson, Anders Gudmundsson, Jenny Rissler, Per Wollmer and Jakob Löndahl

    Citation: BMC Pulmonary Medicine 2018 18:129

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  2. Content type: Research article

    Old age is an important factor that could affect the treatment of early-stage lung cancer. In this study, we evaluated the treatment patterns and outcomes of patients over the age of 80 years who had been diag...

    Authors: Kyungjong Lee, Hye Ok Kim, Hee Kyoung Choi and Gi Hyeon Seo

    Citation: BMC Pulmonary Medicine 2018 18:127

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  3. Content type: Research article

    Most patients with unilateral diaphragm paralysis (UDP) have unexplained dyspnea, exercise limitations, and reduction in inspiratory muscle capacity. We aimed to evaluate the generation of pressure in each hem...

    Authors: Mayra Caleffi-Pereira, Renata Pletsch-Assunção, Letícia Zumpano Cardenas, Pauliane Vieira Santana, Jeferson George Ferreira, Vinícius Carlos Iamonti, Pedro Caruso, Angelo Fernandez, Carlos Roberto Ribeiro de Carvalho and André Luís Pereira Albuquerque

    Citation: BMC Pulmonary Medicine 2018 18:126

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  4. Content type: Research article

    Cardiovascular disease (CVD) is remarkably frequent in patients with chronic obstructive pulmonary disease (COPD). Albuminuria is a marker of vascular endothelial dysfunction and predictor of CVD events. Album...

    Authors: Festo K. Shayo and Janet Lutale

    Citation: BMC Pulmonary Medicine 2018 18:125

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  5. Content type: Research article

    Chronic obstructive pulmonary disease (COPD) with carbon dioxide retention is associated with a worsening clinical condition and the beginning of pulmonary ventilation decompensation. This study aimed to ident...

    Authors: Xia Wei, Nan Yu, Qi Ding, Jingting Ren, Jiuyun Mi, Lu Bai, Jianying Li, Min Qi and Youmin Guo

    Citation: BMC Pulmonary Medicine 2018 18:124

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  6. Content type: Research article

    c-Kit + lung stem cells have been described in the human healthy lung. Their potential relation with smoking and/or chronic obstructive pulmonary disease (COPD) is unknown.

    Authors: Alejandra López-Giraldo, Tamara Cruz, Laureano Molins, Ángela Guirao, Adela Saco, Sandra Cuerpo, Josep Ramirez, Álvar Agustí and Rosa Faner

    Citation: BMC Pulmonary Medicine 2018 18:123

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  7. Content type: Research article

    Self-report questionnaires are commonly used in epidemiology, but may be susceptible to misclassification, especially if answers are given on behalf of others, e.g. children or parents. The aim was to determin...

    Authors: Ingrid N. Kuiper, Cecilie Svanes, Bryndis Benediktsdottir, Randi J. Bertelsen, Lennart Bråbäck, Shyamali C. Dharmage, Mathias Holm, Christer Janson, Rain Jögi, Andrei Malinovschi, Melanie Matheson, Jesús Martínez Moratalla, Francisco Gómez Real, José Luis Sánchez-Ramos, Vivi Schlünssen, Signe Timm…

    Citation: BMC Pulmonary Medicine 2018 18:122

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  8. Content type: Case report

    Crizotinib is a multi-target inhibitor approved for the treatment of advanced non-small-cell lung cancer patients with a ROS1 rearrangement. However, interstitial lung disease is a rare but severe and fatal si...

    Authors: Shibo Wu, Kaitai Liu, Feng Ren, Dawei Zheng and Deng Pan

    Citation: BMC Pulmonary Medicine 2018 18:121

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  9. Content type: Research article

    Vitamin D deficiency has been linked to an increased risk of asthma. This study aimed to quantify the effect of early life vitamin D status on asthma and wheeze later in life.

    Authors: Song-Ying Shen, Wan-Qing Xiao, Jin-Hua Lu, Ming-Yang Yuan, Jian-Rong He, Hui-Min Xia, Xiu Qiu, Kar Keung Cheng and Kin Bong Hubert Lam

    Citation: BMC Pulmonary Medicine 2018 18:120

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  10. Content type: Research article

    Interleukin-5 (IL-5) antibodies represent a promising therapeutic option for patients with severe eosinophilic asthma. To date, no official treatment response criteria exist. In this study, simple criteria for...

    Authors: Nora Drick, Benjamin Seeliger, Tobias Welte, Jan Fuge and Hendrik Suhling

    Citation: BMC Pulmonary Medicine 2018 18:119

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  11. Content type: Research article

    It is widely accepted that exercise capacity in healthy individuals is limited by the cardiac function, while the respiratory system is considered oversized. Although there is physiological, age-related declin...

    Authors: Amir Farkhooy, Johan Bodegård, Jan Erik Erikssen, Christer Janson, Hans Hedenström, Knut Stavem and Andrei Malinovschi

    Citation: BMC Pulmonary Medicine 2018 18:118

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  12. Content type: Research article

    Chronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality around the world. The aim of our study was to determine the association between specific comorbidities and COPD sev...

    Authors: Chantal Raherison, El-Hassane Ouaalaya, Alain Bernady, Julien Casteigt, Cecilia Nocent-Eijnani, Laurent Falque, Frédéric Le Guillou, Laurent Nguyen, Annaig Ozier and Mathieu Molimard

    Citation: BMC Pulmonary Medicine 2018 18:117

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  13. Content type: Research article

    Prognostic stratification of elderly patients with chronic obstructive pulmonary disease (COPD) is difficult due to the wide inter-individual variability in the course of the disease. No marker can exactly str...

    Authors: Domenico Acanfora, Pietro Scicchitano, Mauro Carone, Chiara Acanfora, Giuseppe Piscosquito, Roberto Maestri, Annapaola Zito, Ilaria Dentamaro, Marialaura Longobardi, Gerardo Casucci, Raffaele Antonelli-Incalzi and Marco Matteo Ciccone

    Citation: BMC Pulmonary Medicine 2018 18:116

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  14. Content type: Research article

    Sputum induction is an important noninvasive method for analyzing bronchial inflammation in patients with asthma and other respiratory diseases. Most frequently, ultrasonic nebulizers are used for sputum induc...

    Authors: Sinem Koc-Günel, Ralf Schubert, Stefan Zielen and Martin Rosewich

    Citation: BMC Pulmonary Medicine 2018 18:115

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  15. Content type: Research article

    Pulmonary Mycobacterium avium complex (pMAC) disease is a chronic, slowly progressive disease. The aim of the present study was to determine the association of six-minute walk test (6MWT) parameters with pulmonar...

    Authors: Kazuma Yagi, Takanori Asakura, Ho Namkoong, Shoji Suzuki, Takahiro Asami, Satoshi Okamori, Tatsuya Kusumoto, Yohei Funatsu, Hirofumi Kamata, Tomoyasu Nishimura, Makoto Ishii, Tomoko Betsuyaku and Naoki Hasegawa

    Citation: BMC Pulmonary Medicine 2018 18:114

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  16. Content type: Research article

    The natural history of airway inflammation and symptoms in occupations at risk of asthma is still not fully understood. We aimed to study the evolution during apprenticeship of inflammation markers, bronchial ...

    Authors: Valérie Demange, Denis Zmirou-Navier, Abraham Bohadana and Pascal Wild

    Citation: BMC Pulmonary Medicine 2018 18:113

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  17. Content type: Case report

    Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare cause of pulmonary hypertension that is associated with malignancies and is marked by the presence of non-occlusive tumor emboli and fibrocellular in...

    Authors: Dante A. Suffredini, Jung-Min Lee, Cody J. Peer, Drew Pratt, David E. Kleiner, Jason M. Elinoff and Michael A. Solomon

    Citation: BMC Pulmonary Medicine 2018 18:112

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  18. Content type: Research article

    Pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) is suggested as the consequence of emphysematous destruction of vascular bed and hypoxia of pulmonary microenvironment, mechanisms un...

    Authors: Xiaotong Guo, Yuchun Fan, Jieda Cui, Binwei Hao, Li Zhu, Xiao Sun, Jinxi He, Jiali Yang, Jianda Dong, Yanyang Wang, Xiaoming Liu and Juan Chen

    Citation: BMC Pulmonary Medicine 2018 18:111

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  19. Content type: Research article

    In the Commonwealth of Independent States (CIS) countries epidemiology of Bronchial Asthma (BA) is poorly characterized. The objective of this analysis is to present the prevalence, burden and risk factors ass...

    Authors: Damilya Nugmanova, Lyudmila Sokolova, Yuriy Feshchenko, Liudmila Iashyna, Olga Gyrina, Katerina Malynovska, Ilgar Mustafayev, Gulzar Aliyeva, Janina Makarova, Averyan Vasylyev and Luqman Tariq

    Citation: BMC Pulmonary Medicine 2018 18:110

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  20. Content type: Research article

    Multiple factors are involved in asthma exacerbations, including environmental exposure and viral infections. We aimed to assess the association between severe asthma exacerbations, acute respiratory viral inf...

    Authors: Lusmaia Damaceno Camargo Costa, Paulo Augusto Moreira Camargos, Paul L. P. Brand, Fabíola Souza Fiaccadori, Menira Borges de Lima Dias e Souza, Divina das Dôres de Paula Cardoso, Ítalo de Araújo Castro, Ruth Minamisava and Paulo Sérgio Sucasas da Costa

    Citation: BMC Pulmonary Medicine 2018 18:109

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  21. Content type: Research article

    Vitamin D is involved in the host immune response toward Mycobacterium tuberculosis. However, the efficacy of vitamin D supplementation on sputum conversion, clinical response to treatment, adverse events, and mo...

    Authors: Hong-xia Wu, Xiao-feng Xiong, Min Zhu, Jia Wei, Kai-quan Zhuo and De-yun Cheng

    Citation: BMC Pulmonary Medicine 2018 18:108

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  22. Content type: Research article

    Incorrect inhaler technique is a common cause of poor asthma control. This two-phase pragmatic study evaluated inhaler technique mastery and maintenance of mastery with DuoResp® (budesonide-formoterol [BF]) Sp...

    Authors: David B. Price, Vicky Thomas, P. N. Richard Dekhuijzen, Sinthia Bosnic-Anticevich, Nicolas Roche, Federico Lavorini, Priyanka Raju, Daryl Freeman, Carole Nicholls, Iain R. Small, Erika Sims, Guilherme Safioti, Janice Canvin and Henry Chrystyn

    Citation: BMC Pulmonary Medicine 2018 18:107

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  23. Content type: Research article

    Pulmonary arterial hypertension is a rare, progressive disease with poor prognosis. However, there is limited information available on the characteristics of PAH patients outside of North America and Europe. T...

    Authors: Ana Beatriz Valverde, Juliana M. Soares, Karynna P. Viana, Bruna Gomes, Claudia Soares and Rogerio Souza

    Citation: BMC Pulmonary Medicine 2018 18:106

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  25. Content type: Research article

    Cystic fibrosis (CF) is associated with bacterial pulmonary infections and neutrophil-dominated inflammation in the airways. The aim of this study was to evaluate the neutrophil-derived protein Heparin-binding...

    Authors: Gisela Hovold, Victoria Palmcrantz, Fredrik Kahn, Arne Egesten and Lisa I. Påhlman

    Citation: BMC Pulmonary Medicine 2018 18:104

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  26. Content type: Research article

    “Velcro-type” crackles on chest auscultation are considered a typical acoustic finding of Fibrotic Interstitial Lung Disease (FILD), however whether they may have a role in the early detection of these disorde...

    Authors: Giacomo Sgalla, Simon L. F. Walsh, Nicola Sverzellati, Sophie Fletcher, Stefania Cerri, Borislav Dimitrov, Dragana Nikolic, Anna Barney, Fabrizio Pancaldi, Luca Larcher, Fabrizio Luppi, Mark G. Jones, Donna Davies and Luca Richeldi

    Citation: BMC Pulmonary Medicine 2018 18:103

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  28. Content type: Research article

    The ability of circulating monocytes to develop into lung macrophages and promote lung tissue damage depends upon their phenotypic pattern of differentiation and activation. Whether this phenotypic pattern var...

    Authors: William D. Cornwell, Victor Kim, Xiaoxuan Fan, Marie Elena Vega, Frederick V. Ramsey, Gerard J. Criner and Thomas J. Rogers

    Citation: BMC Pulmonary Medicine 2018 18:101

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  29. Content type: Research article

    The chronic and progressive nature of chronic obstructive pulmonary disease (COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are increasingly being used for inhalation ther...

    Authors: Pablo Altman, Luis Wehbe, Juergen Dederichs, Tadhg Guerin, Brian Ament, Miguel Cardenas Moronta, Andrea Valeria Pino and Pankaj Goyal

    Citation: BMC Pulmonary Medicine 2018 18:100

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  30. Content type: Research article

    Regular airway clearance by chest physiotherapy and/or exercise is critical to lung health in cystic fibrosis (CF). Combination of cycling exercise and chest physiotherapy using the Flutter® device on sputum p...

    Authors: Thomas Radtke, Lukas Böni, Peter Bohnacker, Marion Maggi-Beba, Peter Fischer, Susi Kriemler, Christian Benden and Holger Dressel

    Citation: BMC Pulmonary Medicine 2018 18:99

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  31. Content type: Research article

    The purpose of the current study was to determine the association between sedentary time and physical activity with clinically relevant health outcomes among adults with impaired spirometry and those with or w...

    Authors: Shilpa Dogra, Joshua Good, Matthew P. Buman, Paul A. Gardiner, Jennifer L. Copeland and Michael K. Stickland

    Citation: BMC Pulmonary Medicine 2018 18:98

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  33. Content type: Research article

    Understanding the risk factors that are associated with the development of interstitial lung disease might have an important role in understanding the pathogenetic mechanism of interstitial lung disease as wel...

    Authors: Won-Il Choi, Sonila Dauti, Hyun Jung Kim, Sun Hyo Park, Jae Seok Park and Choong Won Lee

    Citation: BMC Pulmonary Medicine 2018 18:96

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  35. Content type: Research article

    Active pulmonary tuberculosis (TB) is associated with intra-hospital spread of the disease. Expeditious diagnosis and isolation are critical for infection control. However, factors that lead to delayed isolati...

    Authors: Sho Nishiguchi, Shusaku Tomiyama, Izumi Kitagawa and Yasuharu Tokuda

    Citation: BMC Pulmonary Medicine 2018 18:94

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  36. Content type: Research article

    Variation in hospital management of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may prolong length of stay, increasing the risk of hospital-acquired complications and wor...

    Authors: Sachin R. Pendharkar, Maria B. Ospina, Danielle A. Southern, Naushad Hirani, Jim Graham, Peter Faris, Mohit Bhutani, Richard Leigh, Christopher H. Mody and Michael K. Stickland

    Citation: BMC Pulmonary Medicine 2018 18:93

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  37. Content type: Case report

    Plague is a life-threatening disease caused by the bacterium, Yersinia pestis. Madagascar is the leading country for human plague cases worldwide. Human plague is a serious disease, particularly in its septicaemi...

    Authors: Voahangy Andrianaivoarimanana, Eric Bertherat, Rojo Rajaonarison, Tiana Rakotondramaro, Christophe Rogier and Minoarisoa Rajerison

    Citation: BMC Pulmonary Medicine 2018 18:92

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  38. Content type: Research article

    An increasing number of studies using primary human bronchial epithelial cells (BECs) have reported intrinsic differences in the expression of several genes between cells from asthmatic and non-asthmatic donor...

    Authors: Stephen R. Reeves, Kaitlyn A. Barrow, Maria P. White, Lucille M. Rich, Maryam Naushab and Jason S. Debley

    Citation: BMC Pulmonary Medicine 2018 18:91

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  39. Content type: Research article

    lipopolysaccharide-binding protein (LBP) has been to be a surrogate marker of inflammation in OSA. This study aimed to test the hypothesis that the concentration of LBP is elevated in adult patients with obstr...

    Authors: Yinfeng Kong, Zhijun Li, Tingyu Tang, Haiyan Wu, Juan Liu, Liang Gu, Tian Zhao and Qingdong Huang

    Citation: BMC Pulmonary Medicine 2018 18:90

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  40. Content type: Research article

    Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in br...

    Authors: Eric V. Neufeld, Brett A. Dolezal, William Speier and Christopher B. Cooper

    Citation: BMC Pulmonary Medicine 2018 18:89

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  41. Content type: Research article

    Mortality prediction of pneumonia by severity scores in patients with multiple underlying health conditions has not fully been investigated. This prospective cohort study is to identify mortality-associated un...

    Authors: Sugihiro Hamaguchi, Motoi Suzuki, Kota Sasaki, Masahiko Abe, Takao Wakabayashi, Eiichiro Sando, Makito Yaegashi, Shimpei Morimoto, Norichika Asoh, Naohisa Hamashige, Masahiro Aoshima, Koya Ariyoshi and Konosuke Morimoto

    Citation: BMC Pulmonary Medicine 2018 18:88

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  42. Content type: Research article

    In people with cystic fibrosis infection with NonTuberculous Mycobacteria is of increasing prevalence. Mycobacterium abscessus complex is of particular concern and has been associated with adverse clinical outcom...

    Authors: Adrien Tissot, Matthew F. Thomas, Paul A. Corris and Malcolm Brodlie

    Citation: BMC Pulmonary Medicine 2018 18:86

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  43. Content type: Research article

    Non-tuberculous mycobacteria (NTM) infection is an increasing problem worldwide. The epidemiology of NTM in most Asian countries is unknown. This study investigated the epidemiology, and clinical profile of in...

    Authors: Albert Y. H. Lim, Sanjay H. Chotirmall, Eric T. K. Fok, Akash Verma, Partha P. De, Soon Keng Goh, Ser Hon Puah, Daryl E. L. Goh and John A. Abisheganaden

    Citation: BMC Pulmonary Medicine 2018 18:85

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  44. Content type: Research article

    Bronchiectasis is a chronic respiratory condition. Persistent bacterial colonisation in the stable state with increased and sometimes altered bacterial burden during exacerbations are accepted as key features ...

    Authors: Alicia B. Mitchell, Bassel Mourad, Lachlan Buddle, Matthew J. Peters, Brian G. G. Oliver and Lucy C. Morgan

    Citation: BMC Pulmonary Medicine 2018 18:84

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  45. Content type: Review

    Bronchiectasis is a disease associated with chronic progressive and irreversible dilatation of the bronchi and is characterised by chronic infection and associated inflammation. The prevalence of bronchiectasi...

    Authors: Ravishankar Chandrasekaran, Micheál Mac Aogáin, James D. Chalmers, Stuart J. Elborn and Sanjay H. Chotirmall

    Citation: BMC Pulmonary Medicine 2018 18:83

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  46. Content type: Research article

    Lung transplantation is a well-established treatment for end-stage non-cystic fibrosis bronchiectasis (BR), though information regarding outcomes of transplantation remains limited. Our results of lung transpl...

    Authors: Jodie Birch, Syba S. Sunny, Katy L. M. Hester, Gareth Parry, F. Kate Gould, John H. Dark, Stephen C. Clark, Gerard Meachery, James Lordan, Andrew J. Fisher, Paul A. Corris and Anthony De Soyza

    Citation: BMC Pulmonary Medicine 2018 18:82

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  47. Content type: Review

    Bronchiectasis is an incurable lung disease characterised by irreversible airway dilatation. It causes symptoms including chronic productive cough, dyspnoea, and recurrent respiratory infections often requirin...

    Authors: Katy L. M. Hester, Julia Newton, Tim Rapley and Anthony De Soyza

    Citation: BMC Pulmonary Medicine 2018 18:80

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  48. Content type: Review

    Bronchiectasis is a common feature of severe inherited and acquired pulmonary disease conditions. Among inherited diseases, cystic fibrosis (CF) is the major disorder associated with bronchiectasis, while acqu...

    Authors: Jürgen Schäfer, Matthias Griese, Ravishankar Chandrasekaran, Sanjay H. Chotirmall and Dominik Hartl

    Citation: BMC Pulmonary Medicine 2018 18:79

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  49. Content type: Case report

    Occupational lung diseases, such as pneumoconiosis, are one of the health problems of dental workers that have been receiving increasing interest. Pulmonary amyloidosis is a heterogenous group of diseases, and...

    Authors: Taizou Hirano, Tadahisa Numakura, Hiroshi Moriyama, Ryoko Saito, Yutaka Shishikura, Jun Shiihara, Hisatoshi Sugiura and Masakazu Ichinose

    Citation: BMC Pulmonary Medicine 2018 18:77

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  50. Content type: Editorial

    Bronchiectasis has an increasing profile within respiratory medicine. This chronic and irreversible airways disease is common but suffers from a lack of evidenced based therapy for patients and, a lack of unde...

    Authors: Sanjay H. Chotirmall and James D. Chalmers

    Citation: BMC Pulmonary Medicine 2018 18:76

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