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  1. The serum creatinine/cystatin C (Cr/CysC) ratio has attracted attention as a marker for sarcopenia, but has not been studied in patients with idiopathic pulmonary fibrosis (IPF). This study aimed to confirm th...

    Authors: Kohei Fujita, Hirotsugu Ohkubo, Akiko Nakano, Norihisa Takeda, Kensuke Fukumitsu, Satoshi Fukuda, Yoshihiro Kanemitsu, Takehiro Uemura, Tomoko Tajiri, Ken Maeno, Yutaka Ito, Tetsuya Oguri, Yoshiyuki Ozawa, Takayuki Murase and Akio Niimi
    Citation: BMC Pulmonary Medicine 2022 22:203
  2. Since nontuberculous mycobacterial pulmonary disease (NTM-PD) is common in middle-aged/elderly slender women at risk of osteoporosis, we hypothesized that NTM-PD could be associated with osteoporosis. The stud...

    Authors: Hiromu Tanaka, Takanori Asakura, Shoji Suzuki, Satoshi Okamori, Tatsuya Kusumoto, Takunori Ogawa, Shunsuke Uno, Atsuho Morita, Ho Lee, Ho Namkoong, Hirofumi Kamata, Yasunori Sato, Yoshifumi Uwamino, Tomoyasu Nishimura, Makoto Ishii, Koichi Fukunaga…
    Citation: BMC Pulmonary Medicine 2022 22:202
  3. Current management of poorly draining complex effusions favours less invasive image-guided placement of smaller tubes and adjunctive intrapleural fibrinolysis therapy (IPFT). In MIST-2 trial, intrapleural 10 m...

    Authors: Xiong Khee Cheong, Andrea Yu-Lin Ban, Boon Hau Ng, Nik Nuratiqah Nik Abeed, Nik Azuan Nik Ismail, Nik Farhan Nik Fuad, Syed Zulkifli Syed Zakaria, Sheah Lin Ghan and Mohamed Faisal Abdul Hamid
    Citation: BMC Pulmonary Medicine 2022 22:199
  4. Nasal tracheal aspiration (NTA) is a frequently used diagnostic method to assess of infections in the lower airways. However, the validity of the method has not previously been compared to bronchoalveolar lava...

    Authors: Louise Østergaard Andersen, Hanne Vebert Olesen, Anne Helene Spannow and Sune Leisgaard Mørck Rubak
    Citation: BMC Pulmonary Medicine 2022 22:198
  5. Lepidic adenocarcinoma represents a histologic pattern of non-small cell lung cancer that characteristically arises in the lung periphery with tracking alongside pre-existing alveolar walls. Noninvasive and in...

    Authors: Zaheer Akhtar, Leah Laageide, Julian Robles, Christopher Winters, Geoffrey C. Wall, James Mallen and Zeeshan Jawa
    Citation: BMC Pulmonary Medicine 2022 22:197
  6. Long-lasting symptoms following SARS-CoV2-infection have been described in several studies. However, there is only limited knowledge about the ongoing pathophysiology and the association with pathological find...

    Authors: Antje Lehmann, Maximilian Gysan, Dominik Bernitzky, Christina Bal, Helmut Prosch, Sonja Zehetmayer, Ruxandra-Iulia Milos, Karin Vonbank, Wolfgang Pohl, Marco Idzko and Daniela Gompelmann
    Citation: BMC Pulmonary Medicine 2022 22:196
  7. There have been reports of increases in the incidence and prevalence of nontuberculous mycobacterial pulmonary disease (NTM-PD) in several countries, but no studies have analyzed claims data using laboratory t...

    Authors: Jae Hyeon Park, Sue Shin, Taek Soo Kim and Hyunwoong Park
    Citation: BMC Pulmonary Medicine 2022 22:195
  8. Antibiotics are frequently prescribed for acute exacerbations of COPD (AECOPD) even though most do not have a bacterial aetiology. Biomarkers may help clinicians target antibiotic use by identifying AECOPD cau...

    Authors: George Hoult, David Gillespie, Tom M. A. Wilkinson, Mike Thomas and Nick A. Francis
    Citation: BMC Pulmonary Medicine 2022 22:194
  9. Several studies have investigated the correlation between physiological parameters and the risk of acute respiratory distress syndrome (ARDS), in addition, etiology-associated heterogeneity in ARDS has become ...

    Authors: Junwei Wu, Chao Liu, Lixin Xie, Xiang Li, Kun Xiao, Guotong Xie and Fei Xie
    Citation: BMC Pulmonary Medicine 2022 22:193
  10. Curcumin has attracted much attention due to its wide range of therapeutic effects. In this study, we used serum collected from patients undergoing one-lung ventilation (OLV) to establish an in vitro acute lun...

    Authors: Hui-Ting Li, Fang Tan, Tian-Hua Zhang, Long-Hui Cao, Hong-Ying Tan, Wen-Qian Lin, Wei-An Zeng and Xin-Jin Chi
    Citation: BMC Pulmonary Medicine 2022 22:192
  11. Inflammatory myositis, such as dermatomyositis, is sometimes complicated by cancer and is recognized as cancer-associated myositis. Although some autoimmune antibodies are considered to be involved in the deve...

    Authors: Yuki Sato, Yoshinori Tanino, Takefumi Nikaido, Ryuichi Togawa, Takaya Kawamata, Natsumi Watanabe, Riko Sato, Ryuki Yamada, Takumi Onuma, Hikaru Tomita, Mikako Saito, Mami Rikimaru, Julia Morimoto, Yasuhito Suzuki, Hiroyuki Minemura, Junpei Saito…
    Citation: BMC Pulmonary Medicine 2022 22:191
  12. Cardiovascular disease is prevalent in idiopathic pulmonary fibrosis (IPF), yet the extent of left-sided heart failure (HF) burden, whether this has changed with time and whether HF impacts mortality risk in t...

    Authors: Ardita Koteci, Ann D. Morgan, Laura Portas, Hannah R. Whittaker, Constantinos Kallis, Peter M. George and Jennifer K. Quint
    Citation: BMC Pulmonary Medicine 2022 22:190
  13. Single-use flexible bronchoscopes eliminate cross contamination from reusable bronchoscopes and are cost-effective in a number of clinical settings. The present bench study aimed to compare the performance of ...

    Authors: Carla R. Lamb, Ekaterina Yavarovich, Vincent Kang, Elliot L. Servais, Lori B. Sheehan, Sara Shadchehr, James Weldon, Matthew J. Rousseau and Gregory P. Tirrell
    Citation: BMC Pulmonary Medicine 2022 22:189
  14. Most severe, critical, or mortal COVID-19 cases often had a relatively stable period before their status worsened. We developed a deterioration risk model of COVID-19 (DRM-COVID-19) to predict exacerbation ris...

    Authors: Hongbing Peng, Chao Hu, Wusheng Deng, Lingmei Huang, Yushan Zhang, Baowei Luo, Xingxing Wang, Xiaodan Long and Xiaoying Huang
    Citation: BMC Pulmonary Medicine 2022 22:188
  15. Once reserved for the fittest, worldwide altitude travel has become increasingly accessible for ageing and less fit people. As a result, more and more individuals with varying degrees of respiratory conditions...

    Authors: Kirsten Holthof, Pierre-Olivier Bridevaux and Isabelle Frésard
    Citation: BMC Pulmonary Medicine 2022 22:187
  16. Mucociliary clearance (MCC) is an essential defense mechanism in airway epithelia for removing pathogens from the respiratory tract. Impaired ciliary functions and MCC have been demonstrated in asthma and chro...

    Authors: Mineo Katsumata, Tomoyuki Fujisawa, Yosuke Kamiya, Yuko Tanaka, Chiaki Kamiya, Yusuke Inoue, Hironao Hozumi, Masato Karayama, Yuzo Suzuki, Kazuki Furuhashi, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Masato Maekawa, Mitsutoshi Setou, Hiroshi Watanabe…
    Citation: BMC Pulmonary Medicine 2022 22:186
  17. Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation. The decline in forced expiratory volume in one second (FEV1) is considered to be one of the...

    Authors: Hiroyuki Sugawara, Atsushi Saito, Saori Yokoyama, Kazunori Tsunematsu and Hirofumi Chiba
    Citation: BMC Pulmonary Medicine 2022 22:185
  18. The management of asthma, which is one of the major causes of childhood morbidity and mortality has been affected by non-adherence to recommended treatment regimens with severe consequences. The aim of the pre...

    Authors: Eden Kassa, Rahel Argaw Kebede and Bruck Messele Habte
    Citation: BMC Pulmonary Medicine 2022 22:184
  19. Transforming Growth Factor-β1 (TGF-β1) is a genetic modifier in patients with cystic fibrosis (CF). Several single nucleotide polymorphisms (SNPs) of TGF-β1 are associated with neutrophilic inflammation, lung fib...

    Authors: T. Trojan, Miguel A. Alejandre Alcazar, G. Fink, J. C. Thomassen, M. V. Maessenhausen, E. Rietschel, P. M. Schneider and S. van Koningsbruggen-Rietschel
    Citation: BMC Pulmonary Medicine 2022 22:183
  20. Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes a wide range of cognitive impairments. Although COPD-Smoking comorbidity is common, the relationship between smoking and cognit...

    Authors: Feiyan Zeng, Wei Hong, Rujing Zha, Ying Li, Chen Jin, Ying Liu, Hao Liu, Mengqiu Liu, Mei Liu, Fei Xu, Daiju Hu, Hongwen Song, Haiyan Wu, Yongqiang Yu and Xiaochu Zhang
    Citation: BMC Pulmonary Medicine 2022 22:182
  21. Allergic asthma is an allergic inflammatory disease of the airways, in which numerous cell types and cytokines have been shown to contribute to pathogenesis of the disease. Although increased expression of IL-...

    Authors: Yan Li, Feng Lan, Yiran Yang, Yingjie Xu, Yalin Chen, Xiaofeng Qin, Zhe Lv, Wei Wang, Sun Ying and Luo Zhang
    Citation: BMC Pulmonary Medicine 2022 22:180
  22. Anlotinib is a multitarget tyrosine kinase inhibitor for treating patients with advanced non-small cell lung cancer (NSCLC). We aimed to assess the efficacy and safety of anlotinib in elder patients with advan...

    Authors: Wenxian Wang, Lan Shao, Yibing Xu, Zhengbo Song, Guangyuan Lou, Yiping Zhang and Ming Chen
    Citation: BMC Pulmonary Medicine 2022 22:179
  23. Chronic obstructive pulmonary disease (COPD) is a complex, multifactorial, polygenic disease. The rate of occurrence of COPD in the Kashi population (Uyghur) is significantly higher than that observed nationwi...

    Authors: Lifeng Tang, Xuemei Zhong, Hui Gong, Maimaitiaili Tuerxun, Tao Ma, Jie Ren, Chengxin Xie, Aifang Zheng, Zulipikaer Abudureheman, Ayiguzali Abudukadeer, Paierda Aini, Subinuer Yilamujiang and Li Li
    Citation: BMC Pulmonary Medicine 2022 22:178
  24. In patients with acute hypoxemic respiratory failure whose diagnosis is not established after initial evaluation, obtaining a histopathological diagnosis may improve the patients’ prognosis. This study aims to...

    Authors: Shiyao Wang, Yingying Feng, Yi Zhang, Ye Tian, Sichao Gu, Xiaojing Wu, Yiming Feng, Ling Zhao, Min Liu, Dan Wang, Ying Li, Zheng Tian, Shumeng Wang, Xu Huang, Guowu Zhou and Qingyuan Zhan
    Citation: BMC Pulmonary Medicine 2022 22:177
  25. Altered metabolic pathways have recently been considered as potential drivers of idiopathic pulmonary fibrosis (IPF) for the study of drug therapeutic targets. However, our understanding of the metabolite prof...

    Authors: Xiao-hui Yang, Fang-fang Wang, Xiao-sa Chi, Xiao-meng Wang, Jin-peng Cong, Yi Hu and Yu-zhu Zhang
    Citation: BMC Pulmonary Medicine 2022 22:176
  26. Although pulmonary rehabilitation is helpful for patients following lung cancer surgery, rehabilitation is not widely available, due in part to a lack of medical resources. Recent developments in digital healt...

    Authors: Jang Ho Lee, Jae Hwa Jeong, Wonjun Ji, Hui Jeong Lee, Yura Lee, Min-Woo Jo, Seockhoon Chung, Sung-Cheol Yun, Chang-Min Choi, Geun Dong Lee, Sei Won Lee and Jong Won Lee
    Citation: BMC Pulmonary Medicine 2022 22:175
  27. Bronchial asthma is a heterogeneous disease with distinct disease phenotypes and underlying pathophysiological mechanisms. Long non-coding RNAs (lncRNAs) are involved in numerous functionally different biologi...

    Authors: Han Cui, Ruirui Duan, Hongtao Niu, Tao Yu, Ke Huang, Chen Chen, Ke Hao, Ting Yang and Chen Wang
    Citation: BMC Pulmonary Medicine 2022 22:174
  28. As promising novel treatments develop for malignant pleural mesothelioma (MPM), early prognostication has become increasingly important. Circulating and local inflammatory cells are known to play a significant...

    Authors: Duneesha De Fonseka, David T. Arnold, Anna J. Morley, Mary Brett, Nidhi Bhatt, Anthony Edey, Richard Daly, Anna C. Bibby and Nick A. Maskell
    Citation: BMC Pulmonary Medicine 2022 22:173
  29. Cigarette smoking is a risk factor for interstitial lung abnormalities (ILAs) and interstitial lung diseases (ILDs). Investigation defining the relationships between ILAs/ILDs and clinical, radiographic, and p...

    Authors: Rahul G. Sangani, Vishal Deepak, Andrew J. Ghio, Michael J. Forte, Rafia Zulfikar, Zalak Patel, Austin King, Esra Alshaikhnassir, Ghulam Abbas and Jeffrey Vos
    Citation: BMC Pulmonary Medicine 2022 22:172
  30. We aimed to establish the relationships between the expression of microRNAs (miRNAs) and echocardiographic right ventricular (RV) function parameters, and to explore the effectiveness and clinical value of miR...

    Authors: Ran Miao, Juanni Gong, Xiaojuan Guo, Dichen Guo, Xinyuan Zhang, Huimin Hu, Jiuchang Zhong, Yuanhua Yang and Yidan Li
    Citation: BMC Pulmonary Medicine 2022 22:171
  31. Cleaning workers represent a significant proportion of the active population worldwide, with poor remuneration, particularly in developing countries. Despite this, they remain a relatively poorly studied occup...

    Authors: Edinéia Rosa da Paz, Cynthia Mafra Fonseca de Lima, Soraia Nogueira Felix, Bruna Schaeffer, Clóvis Eduardo Santos Galvão, Aristides Tadeu Correia, Renato Fraga Righetti, Milton de Arruda Martins, Iolanda de Fátima Lopes Calvo Tibério and Beatriz Mangueira Saraiva-Romanholo
    Citation: BMC Pulmonary Medicine 2022 22:170
  32. Frequent and highly prevalent as comorbidities in Chronic Obstructive Pulmonary Disease (COPD) patients, both depression and anxiety seem to have an impact on COPD prognosis. However, they are underdiagnosed a...

    Authors: Martínez-Gestoso Sandra, García-Sanz María-Teresa, Carreira José-Martín, Salgado Francisco-Javier, Calvo-Álvarez Uxío, Doval-Oubiña Liliana, Camba-Matos Sandra, Peleteiro-Pedraza Lorena, González-Pérez Miguel-Angel, Penela-Penela Pedro, Vilas-Iglesias Andrés and González-Barcala Francisco-Javier
    Citation: BMC Pulmonary Medicine 2022 22:169
  33. Probiotic might have a role in the prevention of ventilator-associated pneumonia (VAP) among mechanically ventilated patients, but the efficacy and safety remained inconsistent. The aim of this systematic revi...

    Authors: Yue-chen Sun, Chen-yi Wang, Hai-li Wang, Yao Yuan, Jian-hong Lu and Lei Zhong
    Citation: BMC Pulmonary Medicine 2022 22:168
  34. Although several histological studies have documented airway inflammation and remodelling in the small airways of dust-exposed workers, little is known regarding the prevalence and risk factors of small airway...

    Authors: Yali Fan, Ruimin Ma, Xuqin Du, Dandan Chai, Shuangli Yang and Qiao Ye
    Citation: BMC Pulmonary Medicine 2022 22:167
  35. Immune checkpoint inhibitors (ICIs) have achieved promising effects in patients with non-small cell lung cancer (NSCLC). However, not all patients with NSCLC benefit from immunotherapy. There is an urgent need...

    Authors: Yi Yan, Xinyan Wang, Chenan Liu and Junmei Jia
    Citation: BMC Pulmonary Medicine 2022 22:166
  36. Many Hodgkin lymphoma (HL) survivors are at increased risk of subsequent malignant neoplasms (SMN), including lung cancer, due to previous treatment for HL. Lung cancer screening (LCS) detects early-stage lung...

    Authors: Rachel Broadbent, Christopher J. Armitage, Philip Crosbie, John Radford and Kim Linton
    Citation: BMC Pulmonary Medicine 2022 22:165
  37. Exposure to inhalational hazards during post-9/11 deployment to Southwest Asia and Afghanistan puts military personnel at risk for respiratory symptoms and disease. Pulmonary function and qualitative chest hig...

    Authors: Lauren M. Zell-Baran, Stephen M. Humphries, Camille M. Moore, David A. Lynch, Jean-Paul Charbonnier, Andrea S. Oh and Cecile S. Rose
    Citation: BMC Pulmonary Medicine 2022 22:163
  38. The aim of this study was to explore risk factors for the prognosis of lung cancer with simple brain metastasis (LCSBM) patients and to establish a prognostic predictive nomogram for LCSBM patients.

    Authors: Jiaying Yuan, Zhiyuan Cheng, Jian Feng, Chang Xu, Yi Wang, Zixiu Zou, Qiang Li, Shicheng Guo, Li Jin, Gengxi Jiang, Yan Shang and Junjie Wu
    Citation: BMC Pulmonary Medicine 2022 22:162
  39. In dental laboratories, exposure to crystalline silica can occur during procedures that generate suspended mineral dusts, e.g. dispersion of mixing powders, removal of castings from molds grinding, polishing o...

    Authors: Luigi Di Lorenzo, Francesco Inchingolo, Antonella Pipoli, Filippo Cassano, Maria Elena Maggiore, Angelo Michele Inchingolo, Sabino Ceci, Assunta Patano, Giuseppina Malcangi, Antonio Mancini, Giosi Longo, Rossella Attimonelli, Eugenio Maiorano, Rocco Laviano, Nicola Mariano Manghisi, Antonio Scarano…
    Citation: BMC Pulmonary Medicine 2022 22:161
  40. Smoke exposure culminates as a progressive lung complication involving airway inflammation and remodeling. While primary smoke poses the greatest risk, nearly half of the US population is also at risk due to e...

    Authors: Kelsey M. Hirschi-Budge, Kary Y. F. Tsai, Katrina L. Curtis, Gregg S. Davis, Benjamin K. Theurer, Anica M. M. Kruyer, Kyle W. Homer, Ashley Chang, Pam M. Van Ry, Juan A. Arroyo and Paul R. Reynolds
    Citation: BMC Pulmonary Medicine 2022 22:160
  41. Sevoflurane is considered as a lung-protective factor in acute lung injury (ALI), but the underlying molecular mechanism remains largely unknown. The present study identified for the first time that sevofluran...

    Authors: Zhiling Fu, Xiuying Wu, Fushuang Zheng and Yan Zhang
    Citation: BMC Pulmonary Medicine 2022 22:159
  42. High loop gain (unstable ventilatory control) is an important—but difficult to measure—contributor to obstructive sleep apnea (OSA) pathogenesis, predicting OSA sequelae and/or treatment response. Our objectiv...

    Authors: Christopher N. Schmickl, Jeremy E. Orr, Paul Kim, Brandon Nokes, Scott Sands, Sreeganesh Manoharan, Lana McGinnis, Gabriela Parra, Pamela DeYoung, Robert L. Owens and Atul Malhotra
    Citation: BMC Pulmonary Medicine 2022 22:158
  43. The impact of co-infection with other pathogenic microorganisms after initiation of treatment for Mycobacterium avium complex pulmonary disease (MAC-PD) has not been clearly described. This study sought to clarif...

    Authors: Naohisa Urabe, Susumu Sakamoto, Yui Shimanuki, Takumi Kanokogi, Takumi Motohashi, Nanami Anzai, Chiaki Kato, Asuka Yamaguchi, Nozomi Tokita, Sakae Homma and Kazuma Kishi
    Citation: BMC Pulmonary Medicine 2022 22:157
  44. China launched its new round of health care reform to develop primary care in 2009, establishing 954,390 primary care institutions that employed over 10 million staff by 2019. However, some studies have shown ...

    Authors: Xueqin Chen, Wei Sun, Shan Li, Xinmin Wang, Mao Huang and Ningfei Ji
    Citation: BMC Pulmonary Medicine 2022 22:156
  45. Cough is a common complication after pulmonary surgery. Previous studies lacked a standard measure to assess postoperative cough-related quality of life and recovery. The purpose of this study is to compare po...

    Authors: Rongjia Lin, Wen Chen, Leilei Zhu and Xiaojie Pan
    Citation: BMC Pulmonary Medicine 2022 22:154

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