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  1. miR-125b-5p plays an important role in the development of cancer and drug resistance. However, in cisplatin resistance of non-small cell lung cancer (NSCLC), the function and potential mechanism of miR-125b-5p...

    Authors: Qiuyu Tan, Jinzhu Ma, Hao Zhang, Xu Wu, Qiang Li, Xiaoxuan Zuo, Yuxin Jiang, Haijun Liu and Liang Yan
    Citation: BMC Pulmonary Medicine 2022 22:469
  2. Extra-pulmonary multi-organ failure in patients with severe acute respiratory distress syndrome (ARDS) is a major cause of high mortality. Our purpose is to assess whether airway pressure release ventilation (...

    Authors: Aijia Ma, Bo Wang, Jiangli Cheng, Meiling Dong, Yang Li, Canzheng Wei, Yongfang Zhou, Yang Xue, Hui Gao, Lican Zhao, Siyu Li, Yiwei Qin, Mengni Zhang, Qin Wu, Jing Yang and Yan Kang
    Citation: BMC Pulmonary Medicine 2022 22:468
  3. Tripartite motif (TRIM) family genes get involved in the pathogenesis and development of various biological processes; however, the prognostic value of TRIM genes for idiopathic pulmonary fibrosis (IPF) needs ...

    Authors: Mi Zhou, Jie Ouyang, Guoqing Zhang and Xin Zhu
    Citation: BMC Pulmonary Medicine 2022 22:467
  4. ICU-acquired weakness, comprising Critical Illness Polyneuropathy (CIP) and Myopathy (CIM) is associated with immobilization and prolonged mechanical ventilation. This study aims to assess feasibility of early de...

    Authors: Caroline Attwell, Laurent Sauterel, Jane Jöhr, Lise Piquilloud, Thierry Kuntzer and Karin Diserens
    Citation: BMC Pulmonary Medicine 2022 22:466
  5. Despite the growing evidence on efficacy, little is known regarding the cost-utility of Vaxom/Imocur (OM-85 BV) supplementation to decrease the probability of recurrent respiratory tract infections in OM-85 BV...

    Authors: Jefferson Antonio Buendía, Diana Guerrero Patiño and Erika Fernanda Lindarte
    Citation: BMC Pulmonary Medicine 2022 22:465
  6. Fibrinolytic therapy can be effective for management of complex pleural effusions. Tissue plasminogen activator (tPA, 10 mg) and deoxyribonuclease (DNAse) every 12 h with a dwell time of one hour is a common s...

    Authors: Alexandra Townsend, Harsha Raju, Krystina A. Serpa, Rachel Pruett, Syed S. Razi, Francisco A. Tarrazzi, Catherine M. Tami and Mark I. Block
    Citation: BMC Pulmonary Medicine 2022 22:464
  7. This study evaluated the effects of less invasive surfactant administration (LISA) and intubation-surfactant-extubation (InSurE) on bronchopulmonary dysplasia (BPD) in preterm infants with respiratory distress...

    Authors: Chun-cai Xu, Ying-ying Bao, Jing-xin Zhao, Ke Cheng, Ling Sun, Jing-yuan Wu, Ming-yuan Wu and Jia-jun Zhu
    Citation: BMC Pulmonary Medicine 2022 22:462
  8. Mycobacterium avium complex lung disease (MAC-LD) is an infection that is increasing in frequency, associated with substantial disease burden, and often refractory to treatment. Amikacin liposome inhalation suspe...

    Authors: Timothy Aksamit, Jasmanda Wu, Mariam Hassan, Emily Achter and Anjan Chatterjee
    Citation: BMC Pulmonary Medicine 2022 22:461
  9. Pneumonic-type invasive mucinous adenocarcinoma (IMA) was often misdiagnosed as pneumonia in clinic. However, the treatment of these two diseases is different.

    Authors: Shuai Zhang, Xinxin Yu, Yong Huang, Pei Nie, Yan Deng, Ning Mao, Sha Li, Baosen Zhu, Li Wang, Bo Wang and Ximing Wang
    Citation: BMC Pulmonary Medicine 2022 22:460
  10. Diaphragmatic ultrasound has been increasingly used to evaluate diaphragm function. However, current diaphragmatic ultrasound parameters provide indirect estimates of diaphragmatic contractile function, and th...

    Authors: Qiancheng Xu, Xiao Yang, Yan Qian, Chang Hu, Weihua Lu, Shuhan Cai, Bo Hu and Jianguo Li
    Citation: BMC Pulmonary Medicine 2022 22:459
  11. Chronic obstructive pulmonary disease (COPD) is the most common co-morbidity associated with non-small cell lung cancer (NSCLC) patients. Immune checkpoint inhibitors related pneumonitis (CIP) is a common immu...

    Authors: Zhu Zeng, Jingjing Qu, Yake Yao, Fei Xu, Shan Lu, Pei Zhang, Yinan Yao, Ning Li, Jianying Zhou and Yuehong Wang
    Citation: BMC Pulmonary Medicine 2022 22:458
  12. Asthma education programs (AEPs) have been shown to increase quality of life and reduce emergency treatments and hospital admissions. Despite the proven benefits, only a minority of asthma patients attend such...

    Authors: Stefanie Eck, Alexander Hapfelmeier, Klaus Linde, Konrad Schultz, Jochen Gensichen, Linda Sanftenberg, Thomas Kühlein, Stefanie Stark, Ildikó Gágyor, Christian Kretzschmann and Antonius Schneider
    Citation: BMC Pulmonary Medicine 2022 22:457
  13. Expectations can enhance the intensity and the neural processing of breathlessness. Previous breathlessness episodes may influence the perception of subsequent episodes because of psycho-traumatic consequences...

    Authors: Kris Mooren, Kirsten Smit, Yvonne Engels, Daisy Janssen and Judith Godschalx
    Citation: BMC Pulmonary Medicine 2022 22:456
  14. Gefitinib is recommended as a first-line treatment option for elderly patients with non-small cell lung cancer (NSCLC). Because no pharmacokinetics of gefitinib have been examined, we prospectively assessed th...

    Authors: Yuta Nio, Hiroo Ishida, Natsumi Matsumoto, Sojiro Kusumoto, Yutaro Kubota, Takuya Tsunoda, Yasutsuna Sasaki and Ken-ichi Fujita
    Citation: BMC Pulmonary Medicine 2022 22:454
  15. Pulmonary sarcomatoid carcinoma (PSC) is a heterogeneous disease with poor prognosis. It is essential to understand the molecular basis of its progression in order to devise novel therapeutic strategies. The a...

    Authors: Yingying Yu, Xiumei Duan, Shuai Wang, Hua He, Shijie Lan, Zhen Guo and Di Wu
    Citation: BMC Pulmonary Medicine 2022 22:453
  16. Nontuberculous mycobacteria (NTM) usually invades vulnerable hosts. Disseminated NTM (dNTM) infection can affect nearly all organs and be easily misdiagnosed as metastatic carcinoma or other systemic diseases,...

    Authors: Xiaochuan Sun, Ting Zhang, Hongli Sun and Xuefeng Sun
    Citation: BMC Pulmonary Medicine 2022 22:452
  17. Authors: Wen Zhang, Jiang-Ling Wang, Shuang Fu, Jia-Ming Zhou, Ye-Jing Zhu, Shu-Nv Cai, Jun Fang, Xinzhong Chen and Kangjie Xie
    Citation: BMC Pulmonary Medicine 2022 22:451

    The original article was published in BMC Pulmonary Medicine 2022 22:389

  18. Endobronchial ultrasound (EBUS)-guided transbronchial biopsy (TBB) facilitates the diagnosis of various respiratory diseases. The safety of performing EBUS-guided TBB in patients with a finding of pulmonary hy...

    Authors: Yuta Takashima, Naofumi Shinagawa, Daisuke Morinaga, Junichi Nakamura, Megumi Furuta, Tetsuaki Shoji, Hajime Asahina, Eiki Kikuchi, Junko Kikuchi, Jun Sakakibara-Konishi, Ichizo Tsujino and Satoshi Konno
    Citation: BMC Pulmonary Medicine 2022 22:449
  19. Pulmonary rehabilitation (PR) is recommended in the treatment of people with idiopathic pulmonary fibrosis (IPF). Little is known about the experiences of people with IPF of PR. Due to Covid-19 there has been ...

    Authors: Orlagh O’Shea, Grainne Murphy, Luke Forde and Katherine M. A. O’Reilly
    Citation: BMC Pulmonary Medicine 2022 22:448
  20. The allergic phenotype is responsible for more than 50% of severe asthma cases. In a stepwise approach, add-on treatments such as anti-IgE are used for severe allergic asthma (SAA). This study was aimed to des...

    Authors: Carlos A. Torres-Duque, Jaime Ocampo-Gómez, Mauricio Morales Castillo, Diana Cano-Rosales, Ángela Giraldo-Montoya, Freddy Rodríguez, Isabel Palacios-Ortega, Mauricio Durán-Silva, Humberto Reynales and Elizabeth García
    Citation: BMC Pulmonary Medicine 2022 22:447
  21. Obstructive sleep apnea (OSA), nocturnal hypoxemia and excessive daytime sleepiness (EDS) are common comorbidities in people with cystic fibrosis (pwCF). Most of the data showing this originates from children ...

    Authors: Matthias Welsner, Sarah Dietz-Terjung, Florian Stehling, Tim Schulte, Ute Niehammer, Fatma-Ezzahra Gahbiche, Christian Taube, Svenja Strassburg, Christoph Schoebel, Gerhard Weinreich and Sivagurunathan Sutharsan
    Citation: BMC Pulmonary Medicine 2022 22:446
  22. There is limited information on the patient’s perspective of how biologic treatments impact their lives. We conducted a qualitative study to explore the patient’s experience of being considered a super-respond...

    Authors: Joseph W. Lanario, Lucy Cartwright, Rupert C. Jones, Ross Sayers, Michael E. Hyland and Matthew Masoli
    Citation: BMC Pulmonary Medicine 2022 22:445
  23. At present, chronic respiratory diseases are a major burden in terms of morbidity and mortality and are of increasing public health concern in China. Meanwhile, the prevalence of diabetes has increased by more...

    Authors: Wei Li, Yi Ning, Yuan Ma, Xinshan Lin, Sailimai Man, Bo Wang, Chen Wang and Ting Yang
    Citation: BMC Pulmonary Medicine 2022 22:444
  24. Accumulating evidence highlights the critical roles of circular RNAs (circRNAs) in the malignant progression of cancers. In this study, we investigated the expression pattern of a newly identified circRNA (hsa...

    Authors: Bo Yang, Bin Zhang, Qi Qi and Changli Wang
    Citation: BMC Pulmonary Medicine 2022 22:443
  25. Bronchoscopy is commonly utilized for non-surgical sampling of indeterminant pulmonary lesions, but nondiagnostic procedures are common. Accurate assessment of the risk of malignancy is essential for decision ...

    Authors: Diana H. Yu, Majid Shafiq, Hitesh Batra, Marla Johnson, Bailey Griscom, Janna Chamberlin, Lori R. Lofaro, Jing Huang, William A. Bulman, Giulia C. Kennedy, Lonny B. Yarmus, Hans J. Lee and David Feller-Kopman
    Citation: BMC Pulmonary Medicine 2022 22:442
  26. Impaired respiratory function caused by respiratory muscle dysfunction is one of the common consequences of chronic obstructive pulmonary disease (COPD). In this study, two-dimensional shear wave elastography ...

    Authors: Yongjian Chen, Jingyun Li, Bingtian Dong, Zhixing Zhu and Guorong Lyu
    Citation: BMC Pulmonary Medicine 2022 22:441
  27. Authors: Xiong Khee Cheong, Andrea Yu-Lin Ban, Boon Hau Ng, Nik Nuratiqah Nik Abeed, Nik Azuan Nik Ismail, Nik Farhan Nik Fuad, Syed Zulkifli Syed Zakaria, Sheah Lin Ghan and Mohamed Faisal Abdul Hamid
    Citation: BMC Pulmonary Medicine 2022 22:440

    The original article was published in BMC Pulmonary Medicine 2022 22:199

  28. Intrapleural fibrinolytic therapy (IPFT) is one of the treatment options for complex pleural effusion. In this study, the IPFT agent used was alteplase, a tissue plasminogen activator (t-PA). This study aims t...

    Authors: Mohamed Faisal Abdul Hamid, Ahmad Hadyan Husainy Hasbullah, Mas Fazlin Mohamad Jailaini, Nik Nuratiqah Nik Abeed, Boon Hau Ng, Hairulfaizi Haron, Nur Ayub Md Ali, Muhammad Ishamuddin Ismail, Nik Azuan Nik Ismail, Mohd Ramzisham Abdul Rahman and Andrea Yu-Lin Ban
    Citation: BMC Pulmonary Medicine 2022 22:439
  29. Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) have considerably high mortality and re-hospitalisation rate. Diaphragmatic dysfunction (DD) is common in COPD patients. However, whether d...

    Authors: Shuoshuo Wei, Rong Lu, Zhengping Zhang, Faxuan Wang, Hai Tan, Xiaohong Wang, Jinlan Ma, Yating Zhang, Ning Deng and Juan Chen
    Citation: BMC Pulmonary Medicine 2022 22:438
  30. During Iraq-Iran conflict, chemical weapons, particularly SM gas, were used numerous times, whose aftereffects are still present. This study aimed to compare serum proteome in the chronic ML (n = 10) and HC (n...

    Authors: Shahram Parvin, Masoud Arabfard, Ali Ghazvini, Mostafa Ghanei and Ali Najafi
    Citation: BMC Pulmonary Medicine 2022 22:437
  31. Lung cancer surgery is reported as a risk factor for chronic pulmonary aspergillosis (CPA). However, limited data are available on its clinical impact. We aimed to determine the effect of developed CPA after l...

    Authors: Bo-Guen Kim, Yong Soo Choi, Sun Hye Shin, Kyungjong Lee, Sang-Won Um, Hojoong Kim, Yeong Jeong Jeon, Junghee Lee, Jong Ho Cho, Hong Kwan Kim, Jhingook Kim, Young Mog Shim and Byeong-Ho Jeong
    Citation: BMC Pulmonary Medicine 2022 22:436
  32. Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease. COPD is associated with accelerated lung aging. Circadian clock is believed to play important roles in COPD. Although the circ...

    Authors: Lingling Li, Min Zhang, Chunyang Zhao, Yusheng Cheng, Chuanmei Liu and Minhua Shi
    Citation: BMC Pulmonary Medicine 2022 22:435
  33. Effective-component compatibility of Bufei Yishen formula III (ECC-BYF III) demonstrates positive effects on stable chronic obstructive pulmonary disease (COPD).

    Authors: Min-yan Li, Yan-qin Qin, Yan-ge Tian, Kang-chen Li, Brian G. Oliver, Xue-fang Liu, Peng Zhao and Jian-sheng Li
    Citation: BMC Pulmonary Medicine 2022 22:434
  34. It is fundamental to optimize and retain health-related quality of life (HRQoL) in the long term in patients with home mechanical ventilation (HMV). Therefore, this study aimed to evaluate the evolution of the...

    Authors: Carla Ribeiro, Cristina Jácome, Luísa Castro, Sara Conde, Wolfram Windisch and Rui Nunes
    Citation: BMC Pulmonary Medicine 2022 22:433
  35. Pulmonary embolism (PE) is a common and potentially life-threatening condition. Since it is considered a ‘do not miss’ diagnosis, PE tends to be over-investigated beyond the evidence-based clinical decision su...

    Authors: Koshiar Medson, Jimmy Yu, Lovisa Liwenborg, Peter Lindholm and Eli Westerlund
    Citation: BMC Pulmonary Medicine 2022 22:432
  36. Ground glass opacity (GGO) is the main HRCT feature representing alveolitis in systemic sclerosis-associated interstitial lung disease (SSc-ILD), but may also represent other conditions such as atelectasis or ...

    Authors: Össur Ingi Emilsson, Angelica Dessle, Henrik Johansson, Shamisa Adeli, Andrei Malinovschi, Maija-Leena Eloranta and Tomas Hansen
    Citation: BMC Pulmonary Medicine 2022 22:430
  37. Although unmet medical needs for better care of patients with chronic cough exist in Japan, epidemiological information about these patients and their treatments is very limited.

    Authors: Yoko Arai, Kotoba Okuyama, Yoshie Onishi, Jonathan Schelfhout, Shigeru Tokita and Takekazu Kubo
    Citation: BMC Pulmonary Medicine 2022 22:429
  38. This study aimed to evaluate the diagnostic accuracy of pleural fluid (PF) lactate dehydrogenase (LDH) to adenosine deaminase (ADA) (LDH/ADA) ratio for tuberculous pleural effusion (TPE). Especially to explore...

    Authors: Zhi Yan, Jian-Xun Wen, Hua Wang, Ting-Wang Jiang, Jin-Hong Huang, Hong Chen, Li Yan, Zhi-De Hu and Wen-Qi Zheng
    Citation: BMC Pulmonary Medicine 2022 22:428
  39. Currently, the microbial etiology of community-acquired pneumonia in children remains challenging. While Gram stain and sputum culture are commonly used to detect bacterial pathogens, it is unclear whether the...

    Authors: Ruimu Zhang, Yue Wu, Guangcheng Deng and Jikui Deng
    Citation: BMC Pulmonary Medicine 2022 22:427
  40. Chronic cough, more than 8 weeks, can either be without co-morbidity called unexplained chronic cough (UCC) or with co-morbidity called refractory chronic cough (RCC). Using datasets from the Danish National P...

    Authors: Vibeke Backer, Andreas Porsborg, Victor Hansen, Tina Skjold, Johannes Martin Schmid, Mette Kehlet, Christian Torp-Pedersen and Kristian Aasbjerg
    Citation: BMC Pulmonary Medicine 2022 22:426
  41. This national study aimed to investigate the lung ultrasound (LUS) training and practice of respiratory therapists (RTs) in mainland China.

    Authors: Kai Liu, Yu-long Yao, Yu-xian Wang, Bi-lin Wei, Liu-cun Li, Qi-xing Wang, Hui-qing Ge, Er-shan Wang, Li-min Yang, Huan Chen, Yun-qing Yang, Hao Qin, Wen-jun Zhai, Shen-ji Yu, Xiao-ting Wang, Zhe Luo…
    Citation: BMC Pulmonary Medicine 2022 22:425
  42. Massive hemoptysis is a rare but potentially life-threatening condition of patients with cystic fibrosis (CF) and advanced pulmonary disease. Hypertrophied bronchial arteries are understood to cause massive he...

    Authors: Martha Dohna, Hilmar Kühl, Sivagurunathan Sutharsan, Christian Dohna-Schwake, Van Dai Vo Chieu, Susanne Hellms, Norman Kornemann, Diane M. Renz and Michael J. Montag
    Citation: BMC Pulmonary Medicine 2022 22:424
  43. Tracheobronchopathia osteochondroplastica (TO) is a rare condition of unknown etiology. TO is characterized by submucosal nodules, with or without calcifications, protruding in the anterolateral walls of the t...

    Authors: Antoine Dumazet, Claire Launois, Francois Lebargy, Romain Kessler, Hervé Vallerand, Pierre Schmitt, Christophe Hermant, Sandra Dury, Maxime Dewolf, Julien Dutilh, Maher Abouda, Marion Ferreira, Ihab Atallah, Samy Lachkar, Jérémy Charriot, Stéphane Jouneau…
    Citation: BMC Pulmonary Medicine 2022 22:423
  44. Dysphagia occurs in multiple respiratory pathophysiologies, increasing the risk of pulmonary complications secondary to aspiration. Reflux associated aspiration and a dysregulated lung microbiome is implicated...

    Authors: Amal Alamer, Rhys Jones, Michael Drinnan, A. John Simpson, Mike Griffin, Joanne M. Patterson, Abdullah Althuwaybi, Chris Ward and Ian A. Forrest
    Citation: BMC Pulmonary Medicine 2022 22:422
  45. Chronic cough is an extremely common clinical symptom of various diseases. However, the relationship between obstructive sleep apnea (OSA) and chronic cough in the general population has not been sufficiently ...

    Authors: Tae Hoon Kim, I Re Heo and Ho Cheol Kim
    Citation: BMC Pulmonary Medicine 2022 22:419

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