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  1. congenital pulmonary airway malformation (CPAM) is the most frequent congenital lung disorder. CPAM type 1 is the most common subtype, typically having a cystic radiological and histological appearance. Mucino...

    Authors: Timco Koopman, Bart L. Rottier, Arja ter Elst and Wim Timens

    Citation: BMC Pulmonary Medicine 2020 20:52

    Content type: Case report

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  2. Patients with fibrotic interstitial lung disease (FILD) often experience gas exchange abnormalities and ventilatory limitations, resulting in reduced exercise capacity. High-flow nasal cannula (HFNC) oxygen th...

    Authors: Atsushi Suzuki, Masahiko Ando, Tomoki Kimura, Kensuke Kataoka, Toshiki Yokoyama, Eiichi Shiroshita and Yasuhiro Kondoh

    Citation: BMC Pulmonary Medicine 2020 20:51

    Content type: Research article

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  3. Asthma is one of the chronic diseases which affects the airway, and inhalers are the preferred medications to treat this problem. Improper inhalational technique leads to decreased efficacy of the medication b...

    Authors: Tadesse Melaku Abegaz, Efrata Ashuro Shegena, Natnael Fentie Gessie, Eyob Alemayehu Gebreyohanns and Mohammed Assen Seid

    Citation: BMC Pulmonary Medicine 2020 20:48

    Content type: Research article

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  4. Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is associated with infective triggers including bacterial or viral in many cases, and pneumonia is a major contributor to hospitalization f...

    Authors: Sunmin Park, Sang Jun Lee, Beomsu Shin, Seok Jeong Lee, Sang-Ha Kim, Woo Cheol Kwon, Jihye Kim and Myoung Kyu Lee

    Citation: BMC Pulmonary Medicine 2020 20:47

    Content type: Research article

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  5. Lung transplantation (LTx) is still limited by the shortage of suitable donor lungs. Developing flexible surgical procedures can help to increase the chances of LTx by unfolding recipient-to-donor matching opt...

    Authors: Haruchika Yamamoto, Kentaroh Miyoshi, Shinji Otani, Takeshi Kurosaki, Seiichiro Sugimoto, Masaomi Yamane, Shinichi Toyooka, Motomu Kobayashi and Takahiro Oto

    Citation: BMC Pulmonary Medicine 2020 20:46

    Content type: Case report

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  6. Bronchiectasis is a chronic infectious respiratory disease with diverse causes and ethnic or geographic differences. However, few large-scale studies of its etiology have been conducted in Asia. This study aim...

    Authors: Hung-Yu Huang, Fu-Tsai Chung, Chun-Yu Lo, Horng-Chyuan Lin, Yu-Tung Huang, Chih-Hsin Yeh, Chang-Wei Lin, Yu-Chen Huang and Chun-Hua Wang

    Citation: BMC Pulmonary Medicine 2020 20:45

    Content type: Database

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  7. Lung cancer surgery is associated with a high incidence of postoperative pulmonary complications (PPCs). Preliminary evidence suggests that ERAS processes can reduce overall incidence of PPCs as short- and lon...

    Authors: Yu Zheng, Mao Mao, Meifang Ji, Qiugang Zheng, Liang Liu, Zhigang Zhao, Haiming Wang, Xiangyang Wei, Yulong Wang, Jiamin Chen, Huiqing Zhou, Qiaoqiao Liang, Ying Chen, Xintong Zhang, Lu Wang, Yihui Cheng…

    Citation: BMC Pulmonary Medicine 2020 20:44

    Content type: Study protocol

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  8. Descending necrotizing mediastinitis is a severe infection of the mediastinum. This syndrome manifests as fever and chest pain following cough and sputum production. A 49-year-old woman presented with fever an...

    Authors: Rui-hai Ye, Jun-chao Yang, Hui-hua Hong, Yu-ping Mao, Yuan-hong Zhu, Yu Cao and Zhen Wang

    Citation: BMC Pulmonary Medicine 2020 20:43

    Content type: Case report

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  9. Because of its analgesic and light sedative properties, the highly selective alpha-2 adrenergic receptor agonist dexmedetomidine (DEX) has been suggested for the treatment of septic patients, but its effect on...

    Authors: Peifen Chen, Jihong Jiang, Yunhe Zhang, Guobao Li, Zhihui Qiu, Mitchell M. Levy and Baoji Hu

    Citation: BMC Pulmonary Medicine 2020 20:42

    Content type: Research article

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  10. Targeted lung denervation (TLD) is a bronchoscopically delivered ablation therapy that selectively interrupts pulmonary parasympathetic nerve signaling. The procedure has the potential to alter airway smooth m...

    Authors: Dirk-Jan Slebos, Bruno Degano, Arschang Valipour, Pallav L. Shah, Gaetan Deslée and Frank C. Sciurba

    Citation: BMC Pulmonary Medicine 2020 20:41

    Content type: Study protocol

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  11. Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approa...

    Authors: Raquel Nazareth, Maria-Jesus Chasqueira, Maria-Lúcia Rodrigues, Carolina Paulino, Catarina Conceição, Lia Lêdo, Úrsula Segura, Madalena Santos, António Messias, Pedro Póvoa and Paulo Paixão

    Citation: BMC Pulmonary Medicine 2020 20:39

    Content type: Research article

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  12. Massive hemoptysis is a serious complication in Cystic Fibrosis (CF), occurring commonly in older patients. Bronchial artery embolization (BAE) can be performed to stop the bleeding. BAE is generally safe and ...

    Authors: V. Terlizzi, M. Botti, G. Gabbani, F. Fanelli, M. De Martino and G. Taccetti

    Citation: BMC Pulmonary Medicine 2020 20:38

    Content type: Case report

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  13. Prolonged and difficult weaning is associated with higher rates of complications and mortality. Therefore, it is important to identify the associated factors.

    Authors: Renyu Ding, Yulan Meng, Xingjuan Jia and Xiaochun Ma

    Citation: BMC Pulmonary Medicine 2020 20:37

    Content type: Case report

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  14. Lung cancer is the most common cause of cancer related death worldwide and survival is poor. Patients with lung cancer may develop a critical illness, but it is unclear what features are associated with an Int...

    Authors: Kathryn Puxty, Christopher H. Grant, Philip McLoone, Billy Sloan, Tara Quasim, Kate Hulse and David S. Morrison

    Citation: BMC Pulmonary Medicine 2020 20:36

    Content type: Research article

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  15. Hump-nosed viper bite, the commonest venomous snake bite in Sri Lanka, is associated with significant morbidity. Specific anti-venom is not available for hump-nosed viper envenomation which is usually managed ...

    Authors: Arthihai Srirangan, Jagath Pushpakumara and Kamani Wanigasuriya

    Citation: BMC Pulmonary Medicine 2020 20:35

    Content type: Case report

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  16. Pulmonary alveolar proteinosis (PAP) is a very rare lung disease and its prevalence and incidence remain unclear. The prevalence and incidence of PAP were investigated by using nationwide claims data from the ...

    Authors: Hee-young Yoon, Ji Hyeon Kim, Ye-Jee Kim and Jin Woo Song

    Citation: BMC Pulmonary Medicine 2020 20:34

    Content type: Research article

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  17. Early detection of pulmonary contamination in children with cystic fibrosis (CF) is essential since these children are vulnerable to Pseudomonas aeruginosa (P. aeruginosa) colonization. In Iran, home nebulization...

    Authors: Seyed Ahmad Tabatabaii, Ghamartaj Khanbabaee, Saeed Sadr, Nazanin Farahbakhsh, Maryam Kazemi Aghdam, Saran Lotfollahzadeh, Amirhossein Hosseini, Naghi Dara, Mohammad Nanbakhsh and Fatemeh Abdollah Gorji

    Citation: BMC Pulmonary Medicine 2020 20:33

    Content type: Research article

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  18. Chronic hypersensitivity pneumonitis (cHP) is a disease caused by exposure to inhaled environmental antigens. Diagnosis of cHP is influenced by the awareness of the disease prevalence, which varies significant...

    Authors: Jessie P. Gu, Chen-Liang Tsai, Nicholas G. Wysham and Yuh-Chin T. Huang

    Citation: BMC Pulmonary Medicine 2020 20:32

    Content type: Research article

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  19. Obstructive sleep apnea syndrome (OSAS) is a common disorder that is accompanied by structural brain changes. This meta-analysis aimed to evaluate the effect of OSAS on the serum levels of astrocytic protein (...

    Authors: Farzad Rezaei, Hooshyar Abbasi, Masoud Sadeghi and Mohammad Moslem Imani

    Citation: BMC Pulmonary Medicine 2020 20:31

    Content type: Research article

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  20. Cystic airspace is an uncommon imaging manifestation involved in non-small lung cancer (NSCLC). Diffuse cystic lesion is even rarer as pulmonary manifestation of NSCLC. In the present study, we reported a rare...

    Authors: Xianhua Gui, Jingjing Ding, Yan Li, Min Yu, Tingting Chen, Mei Huang and Yonglong Xiao

    Citation: BMC Pulmonary Medicine 2020 20:30

    Content type: Case report

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  21. Chronic obstructive pulmonary disease (COPD) is combination of progressive lung diseases. The diagnosis of COPD is generally based on the pulmonary function testing, however, difficulties underlie in prognosis...

    Authors: Kazushi Matsumura and Shigeaki Ito

    Citation: BMC Pulmonary Medicine 2020 20:29

    Content type: Technical advance

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  22. The risk of injury directly related to hospitalization for motor vehicle accidents (MVAs) in the obstructive sleep apnea (OSA) patients has not been thoroughly understood. Our study aimed to examine the associ...

    Authors: Yi-Chang Lin, Tien-Yu Chen, Wu-Chien Chien, Chi-Hsiang Chung, Hsin-An Chang, Yu-Chen Kao, Chien-Sung Tsai, Chih-Sheng Lin and Nian-Shen Tzeng

    Citation: BMC Pulmonary Medicine 2020 20:28

    Content type: Research article

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  23. Idiopathic pulmonary fibrosis (IPF) is a progressive and fibrosing lung disease with poor prognosis. Pirfenidone and nintedanib are anti-fibrotic drugs used for patients with IPF. These drugs reduce the rate o...

    Authors: Takumi Yoshikawa, Mitsuo Otsuka, Hirofumi Chiba, Kimiyuki Ikeda, Yuki Mori, Yasuaki Umeda, Hirotaka Nishikiori, Koji Kuronuma and Hiroki Takahashi

    Citation: BMC Pulmonary Medicine 2020 20:27

    Content type: Research article

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  24. IL-17A directly induces epithelial-mesenchymal transition (EMT) in alveolar epithelial cells. It could coordinate with cigarette smoke extract (CSE) to promote proliferation of bronchial epithelial cells. In t...

    Authors: Libing Ma, Ming Jiang, Xiaoli Zhao, Jingyi Sun, Qilu Pan and Shuyuan Chu

    Citation: BMC Pulmonary Medicine 2020 20:26

    Content type: Research article

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  25. Interstitial lung disease (ILD) is the most common and important pulmonary manifestation of rheumatoid arthritis (RA). A radiological honeycomb pattern has been described in diverse forms of ILD that can impac...

    Authors: Hideaki Yamakawa, Shintaro Sato, Tomotaka Nishizawa, Rie Kawabe, Tomohiro Oba, Akari Kato, Masanobu Horikoshi, Keiichi Akasaka, Masako Amano, Hiroki Sasaki, Kazuyoshi Kuwano and Hidekazu Matsushima

    Citation: BMC Pulmonary Medicine 2020 20:25

    Content type: Research article

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  26. Lung cancer is the leading cause of cancer mortality in Australia. Guidelines suggest that patients with suspected lung cancer on thoracic imaging be referred for urgent specialist review. However, the term “s...

    Authors: P. Brownell, F. Piccolo, F. Brims, R. Norman and D. Manners

    Citation: BMC Pulmonary Medicine 2020 20:24

    Content type: Research article

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  27. Recent research has proposed an association between desaturation during a six minute walking test (6MWT) and osteoporosis in an elderly group of individuals with non-cystic fibrosis bronchiectasis. A causative...

    Authors: Owen W. Tomlinson and Dimitris Vlachopoulos

    Citation: BMC Pulmonary Medicine 2020 20:23

    Content type: Correspondence

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  28. We investigated the association between a combination of two markers, peripheral (PEC) and bronchoalveolar lavage (BAL) eosinophil percentage (BEP), and oxygen requirements in patients with acute eosinophilic ...

    Authors: Joon Young Choi, Jeong Uk Lim, Ho Jung Jeong, Ji Eun Lee and Chin Kook Rhee

    Citation: BMC Pulmonary Medicine 2020 20:22

    Content type: Research article

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  29. Lung fibrosis is a serious life-threatening condition whose manifestation varies according to the localization and characteristics of fibroblasts, which are considered heterogeneous. Therefore, to better under...

    Authors: Sayomi Matsushima, Yoichiro Aoshima, Taisuke Akamatsu, Yasunori Enomoto, Shiori Meguro, Isao Kosugi, Hideya Kawasaki, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Kazuhito Funai, Takafumi Suda and Toshihide Iwashita

    Citation: BMC Pulmonary Medicine 2020 20:21

    Content type: Research article

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  30. Both mitophagy, a selective mechanism for clearance of mitochondria, and mitochondrial biogenesis are key processes determining mitochondrial content and oxidative capacity of the musculature. Abnormalities in...

    Authors: Pieter A. Leermakers, Alexander H. V. Remels, Ramon C. J. Langen, Annemie M. W. J. Schols and Harry R. Gosker

    Citation: BMC Pulmonary Medicine 2020 20:20

    Content type: Research article

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  31. Previous studies demonstrated an important role for connexin 43 (Cx43) in the regulation of apoptosis by influencing mitochondrial functions. This study aimed to investigate the relationship between Cx43 and l...

    Authors: Jia-wei Ma, Dan-dan Ji, Qian-qian Li, Ting Zhang and Liang Luo

    Citation: BMC Pulmonary Medicine 2020 20:19

    Content type: Research article

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  32. Community-acquired pneumonia (CAP) is one of the leading causes of morbidity and mortality worldwide, often leading to hospital admissions. In Portugal, the factors associated with in-hospital mortality due to...

    Authors: Ezequiel Pessoa, Cristina Bárbara, Laura Viegas, Andreia Costa, Matilde Rosa and Paulo Nogueira

    Citation: BMC Pulmonary Medicine 2020 20:18

    Content type: Research article

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  33. Following publication of the original article [1], the authors flagged that the article had published with an error in ‘Table 1’.

    Authors: Anke Kindermann, Leonore Binder, Jan Baier, Beate Gündel, Andreas Simm, Roland Haase and Babett Bartling

    Citation: BMC Pulmonary Medicine 2020 20:17

    Content type: Correction

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    The original article was published in BMC Pulmonary Medicine 2019 19:245

  34. The 2013 update of the Infection Prevention and Control (IP&C) Guideline outlined recommendations to prevent the spread of CF respiratory pathogens. We aimed to investigate the current infection control practi...

    Authors: Rebecca Elizabeth Stockwell, Michelle ELizabeth Wood, Emma Ballard, Vanessa Moore, Claire Elizabeth Wainwright and Scott Cameron Bell

    Citation: BMC Pulmonary Medicine 2020 20:16

    Content type: Research article

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  35. The understanding of the epidemiology of bronchiectasis is still affected by major limitations with very few data published worldwide. The aim of this study was to estimate the epidemiological burden of bronch...

    Authors: Stefano Aliberti, Giovanni Sotgiu, Francesco Lapi, Andrea Gramegna, Claudio Cricelli and Francesco Blasi

    Citation: BMC Pulmonary Medicine 2020 20:15

    Content type: Research article

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  36. Dyspnea, fatigue, and decline in sleep quality are symptoms of chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation programs have been shown to ameliorate dyspnea and fatigue. However, only a...

    Authors: Leandro Nobeschi, Juliana Zangirolami-Raimundo, Priscila Kessar Cordoni, Selma Denis Squassoni, Elie Fiss, Andrés Ricardo Pérez-Riera, Luiz Carlos de Abreu and Rodrigo Daminello Raimundo

    Citation: BMC Pulmonary Medicine 2020 20:14

    Content type: Research article

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  37. Adenosine deaminase (ADA) activity is typically elevated in patients with tuberculous pleural effusion (TPE), but low ADA has occasionally been reported in patients with TPE. The characteristics of these patie...

    Authors: Sae Byol Kim, Beomsu Shin, Ji-Ho Lee, Seok Jeong Lee, Myoung Kyu Lee, Won-Yeon Lee, Suk Joong Yong and Sang-Ha Kim

    Citation: BMC Pulmonary Medicine 2020 20:13

    Content type: Research article

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  38. Persistent hypercapnia after COPD exacerbation is associated with excess mortality and early rehospitalization. High Flow Nasal cannula (HFNC), may be theoretically an alternative to long-term noninvasive vent...

    Authors: Lara Pisani, Sara Betti, Carlotta Biglia, Luca Fasano, Vito Catalanotti, Irene Prediletto, Vittoria Comellini, Letizia Bacchi-Reggiani and Stefano Nava FERS

    Citation: BMC Pulmonary Medicine 2020 20:12

    Content type: Research article

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  39. Chronic obstructive pulmonary disease (COPD) is the fifth leading cause of death in China with a reported prevalence of 8.2% people aged ≥40 years. It is recommended that Chinese physicians follow Global Initi...

    Authors: Ting Yang, Baiqiang Cai, Bin Cao, Jian Kang, Fuqiang Wen, Wanzhen Yao, Jinping Zheng, Xia Ling, Hongyan Shang and Chen Wang

    Citation: BMC Pulmonary Medicine 2020 20:11

    Content type: Study protocol

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  40. Due to the acquired drug resistance, the potency of cisplatin-based chemotherapy is limited in lung cancer, which is a big obstacle in clinical treatment of lung cancer. Abundant evidence has revealed that cir...

    Authors: Zhihui Wu, Qiang Gong, Yan Yu, Jialin Zhu and Wencan Li

    Citation: BMC Pulmonary Medicine 2020 20:10

    Content type: Research article

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  41. Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was t...

    Authors: Johanna Pakkasela, Pinja Ilmarinen, Jasmin Honkamäki, Leena E. Tuomisto, Heidi Andersén, Päivi Piirilä, Hanna Hisinger-Mölkänen, Anssi Sovijärvi, Helena Backman, Bo Lundbäck, Eva Rönmark, Hannu Kankaanranta and Lauri Lehtimäki

    Citation: BMC Pulmonary Medicine 2020 20:9

    Content type: Research article

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  42. Scleromyxedema is a progressive, systemic connective tissue disorder characterized by fibro-mucous skin lesions and increased serum monoclonal immunoglobulin levels. Pulmonary involvement occurs in a subset of...

    Authors: Mazen Kreidy, Ali Al-Hilli, Ralph Yachoui and Jeffrey Resnick

    Citation: BMC Pulmonary Medicine 2020 20:8

    Content type: Case report

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  43. Pulse oximetry is widely used in the clinical setting. The purpose of this validation study was to investigate the level of agreement between oxygen saturations measured by pulse oximeter (SpO2) and arterial bloo...

    Authors: Janine Pilcher, Laura Ploen, Steve McKinstry, George Bardsley, Jimmy Chien, Lesley Howard, Sharon Lee, Lutz Beckert, Maureen Swanney, Mark Weatherall and Richard Beasley

    Citation: BMC Pulmonary Medicine 2020 20:7

    Content type: Research article

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  44. The purpose of this study was to evaluate the value of serum krebs von den lungen-6 (KL-6) level as a diagnostic indicator for connective tissue disease associated with interstitial lung disease (CTD-ILD).

    Authors: Hua Ma, Junhui Lu, Yuanyuan Song, Huixuan Wang and Songlou Yin

    Citation: BMC Pulmonary Medicine 2020 20:6

    Content type: Research article

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  45. Simultaneous infection in tuberculosis (TB) is rare. The mixed infection between Streptococcus anginosus group (SAG) and M. tuberculosis (MTB) has not been reported in children. The aim of this report was to desc...

    Authors: Napoleon González Saldaña, José Iván Castillo Bejarano, Marte Hernández Porras, Eduardo Arias de la Garza, Sofia Fortes Gutiérrez, Jose Luis Copado Gutiérrez and Hugo Juarez Olguin

    Citation: BMC Pulmonary Medicine 2020 20:5

    Content type: Case report

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  46. Marfan Syndrome (MFS) is a heritable connective tissue disorder with a high degree of clinical variability including respiratory diseases; a rare case of MFS with massive intrathoracic bleeding has been report...

    Authors: Yuki Yabuuchi, Hitomi Goto, Mizu Nonaka, Hiroaki Tachi, Tatsuya Akiyama, Naoki Arai, Hiroaki Ishikawa, Kentaro Hyodo, Kenji Nemoto, Yukiko Miura, Isano Hase, Shingo Usui, Shuji Oh-ishi, Kenji Hayashihara, Takefumi Saito and Tatsuya Chonan

    Citation: BMC Pulmonary Medicine 2020 20:4

    Content type: Case report

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  47. The two 52-week INPULSIS trials investigated nintedanib versus placebo in patients with IPF, FVC ≥50% predicted and DLco 30–79% predicted. The 24-week INSTAGE trial investigated nintedanib plus sildenafil vers...

    Authors: Luca Richeldi, Martin Kolb, Stéphane Jouneau, Wim A. Wuyts, Birgit Schinzel, Susanne Stowasser, Manuel Quaresma and Ganesh Raghu

    Citation: BMC Pulmonary Medicine 2020 20:3

    Content type: Research article

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