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  1. NLR is a systemic inflammatory marker that have been associated with overall survival in patients with some rapidly progressive disease. There are few data about the diagnostic and predictive value of NLR in a...

    Authors: Tao Liu, Wen Li, Zehao Zhang, Ting Jiang, Yu Fei, Jing Huang and Qibing Xie
    Citation: BMC Pulmonary Medicine 2022 22:316
  2. In women, slender body habitus has been reported to be one of the predisposing factors underlying the development and poor prognosis of non-tuberculous mycobacterial lung disease (NTM-LD). Given the lack of nu...

    Authors: Yumi Takayama, Takamasa Kitajima, Noritsugu Honda, Naoki Sakane, Yukina Yumen, Motonari Fukui and Narumi Nagai
    Citation: BMC Pulmonary Medicine 2022 22:315
  3. Acute respiratory distress syndrome (ARDS) is a rapidly progressive and fatal respiratory failure disease that often occurs in critically ill patients. Since ARDS is associated with immune dysregulation and co...

    Authors: Shiyu Nie, Hongjin Wang, Qiuyu Liu, Ze Tang, Wu Tao and Nian Wang
    Citation: BMC Pulmonary Medicine 2022 22:314
  4. The disease course of idiopathic pulmonary fibrosis (IPF) is progressive and occasionally, other types of interstitial lung disease (ILD) may progress similarly to IPF. This study aimed to evaluate risk factor...

    Authors: Minna Mononen, Eeva Saari, Hannele Hasala, Hannu-Pekka Kettunen, Sanna Suoranta, Hanna Nurmi, Miia Kärkkäinen, Tuomas Selander, Jukka Randell, Jari Laurikka, Toomas Uibu, Heikki Koskela, Riitta Kaarteenaho and Minna Purokivi
    Citation: BMC Pulmonary Medicine 2022 22:313
  5. Researchers have linked cardiovascular disease (CVD) with advancing age; however, how it drives disease progression in elderly severe community acquired pneumonia (SCAP) patients is still unclear. This study a...

    Authors: Linjing Gong, Dingxiu He, Dong Huang, Zhenru Wu, Yujun Shi and Zongan Liang
    Citation: BMC Pulmonary Medicine 2022 22:312
  6. The purpose of this study was to evaluate the usefulness of intraprocedural CT and prior PET/CT fusion imaging in improving the diagnostic yield of CT-guided transthoracic core-needle biopsy (CNB) in lung masses.

    Authors: Yue Lin, Yanyan Xu, Jie Lin, Liping Fu, Hongliang Sun, Zhenguo Huang, Bee Yen Ooi and Sheng Xie
    Citation: BMC Pulmonary Medicine 2022 22:311
  7. High mobility group protein B2 (HMGB2) is a multifunctional protein that plays various roles in different cellular compartments. Moreover, HMGB2 serves as a potential prognostic biomarker and therapeutic targe...

    Authors: Xie Qiu, Wei Liu, Yifan Zheng, Kai Zeng, Hao Wang, Haijun Sun and Jianhua Dai
    Citation: BMC Pulmonary Medicine 2022 22:310

    The Correction to this article has been published in BMC Pulmonary Medicine 2022 22:378

  8. Tuberculosis (TB) is one of the main infectious diseases that seriously threatens global health, while diagnostic delay (DD) and treatment dramatically threaten TB control.

    Authors: Xue-han Zhu, Ning-ning Tao, Qian-yun Zhang, Wan-mei Song, Qi-qi An, Si-qi Liu, Yi-fan Li, Fei Long and Huai-chen Li
    Citation: BMC Pulmonary Medicine 2022 22:309
  9. Although diffuse alveolar damage (DAD) is a histopathological hallmark of acute respiratory distress syndrome (ARDS), its detection without lung biopsy is challenging. In patients with ARDS, the specificity of...

    Authors: Ryosuke Imai, Daisuke Yamada, Yutaka Tomishima, Tomoaki Nakamura, Clara So, Shosei Ro, Kohei Okafuji, Atsushi Kitamura, Torahiko Jinta and Naoki Nishimura
    Citation: BMC Pulmonary Medicine 2022 22:308
  10. To evaluate the diagnostic value of tumor M2-pyruvate kinase (TuM2-PK) and carcinoembryonic antigen (CEA) levels in both pleural effusion and serum in the differential diagnosis of benign and malignant pleural...

    Authors: Tiantian Zhang, Wei Liu, Li Li, Zou Jue and Chunhua Xu
    Citation: BMC Pulmonary Medicine 2022 22:307
  11. Acute exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) contributes significantly to mortality among patients with COPD in Intensive care unit (ICU). This study aimed to develop a nomogram to pred...

    Authors: Jiang-Chen Peng, Wen-Wen Gong, Yan Wu, Tian-Yi Yan and Xiao-Yan Jiang
    Citation: BMC Pulmonary Medicine 2022 22:306
  12. Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) is a systemic disease that involves the infiltration of IgG4-positive plasma cells in multiple organs. Kimura disease (KD) presents as subcutaneous masses on ...

    Authors: Ye Lu, Junxiu Liu, Hengyi Yan, Wei Feng, Li Zhao and Yu Chen
    Citation: BMC Pulmonary Medicine 2022 22:305
  13. Noninvasive ventilation (NIV) has been widely used in critically ill patients after extubation. However, NIV failure is associated with poor outcomes. This study aimed to determine early predictors of NIV fail...

    Authors: Huan Wang, Qin-Yu Zhao, Jing-Chao Luo, Kai Liu, Shen-Ji Yu, Jie-Fei Ma, Ming-Hao Luo, Guang-Wei Hao, Ying Su, Yi-Jie Zhang, Guo-Wei Tu and Zhe Luo
    Citation: BMC Pulmonary Medicine 2022 22:304
  14. Hospital work environment contains various biological and chemical exposures that can affect indoor air quality and have impact on respiratory health of the staff. The objective of this study was to investigat...

    Authors: Behzad Heibati, Maritta S. Jaakkola, Taina K. Lajunen, Alan Ducatman, Rahmat Veysi, Ali Karimi and Jouni J. K. Jaakkola
    Citation: BMC Pulmonary Medicine 2022 22:303
  15. Pulmonary rehabilitation is recommended for most patients with chronic obstructive pulmonary disease (COPD). Accordingly, the aim of this study was to explore the feasibility of devising a pulmonary rehabilita...

    Authors: Mathanki Sooriyakanthan, Mark W. Orme, Kanagasabai Sivapalan, Gowry Selvaratnam, Sally J. Singh and Savithri Wimalasekera
    Citation: BMC Pulmonary Medicine 2022 22:302
  16. Little is known about the relationship between integrin subunit alpha V (ITGAV) and cancers, including small cell lung cancer (SCLC).

    Authors: Yu-Lu Tang, Guo-Sheng Li, Dong-Ming Li, Deng Tang, Jie-Zhuang Huang, Hao Feng, Rong-Quan He, Zhi-Guang Huang, Yi-Wu Dang, Jin-Liang Kong, Ting-Qing Gan, Hua-Fu Zhou, Jing-Jing Zeng and Gang Chen
    Citation: BMC Pulmonary Medicine 2022 22:300
  17. To investigate the circumstances that lead to acute exacerbation readmission of elderly patients with chronic obstructive pulmonary disease (COPD) within 30 days and to explore the influencing factors of readm...

    Authors: Hong-Yan Lu, Rui Zhang, Yan Chang, Xiao-Na Zhang, Jie Zhao, Xin-Dan Li and Xiang-Kai Feng
    Citation: BMC Pulmonary Medicine 2022 22:299
  18. Recent years, idiopathic pulmonary fibrosis (IPF) is thought to be a disease of alveoli as well as small airways. This study aimed to demonstrate the clinical feature, predictor, and prognosis of small airway ...

    Authors: Xinran Zhang, Bingbing Xie, Chenjun Ban, Yanhong Ren, Qiao Ye, Min Zhu, Yan Liu, Shu Zhang, Jing Geng, Dingyuan Jiang and Huaping Dai
    Citation: BMC Pulmonary Medicine 2022 22:297
  19. Coronavirus disease 2019-associated acute respiratory distress syndrome (COVID-19 ARDS) seems to differ from the “classic ARDS”, showing initial significant hypoxemia in the face of relatively preserved compli...

    Authors: Lucia Zacchetti, Luca Longhi, Isabella Bianchi, Maria Di Matteo, Filippo Russo, Lucia Gandini, Leonardo Manesso, Martina Monti, Roberto Cosentini, Fabiano Di Marco, Stefano Fagiuoli, Lorenzo Grazioli, Paolo Gritti, Fabio Previdi, Michele Senni, Marco Ranieri…
    Citation: BMC Pulmonary Medicine 2022 22:296
  20. Connective tissue disease associated pulmonary hypertension (CTD-PH) is classified as a subgroup of WHO group 1 PH, also called pulmonary arterial hypertension (PAH). However, not all CTD-PH fit hemodynamic de...

    Authors: Xingbei Dong, Yue Shi, Ying Xia, Xiao Zhang, Junyan Qian, Jiuliang Zhao, Jinmin Peng, Qian Wang, Li Weng, Mengtao Li, Bin Du and Xiaofeng Zeng
    Citation: BMC Pulmonary Medicine 2022 22:295
  21. Few studies have assessed lung function in Hispanic subjects recovering from mild COVID-19. Therefore, we examined the prevalence of impaired pulmonary diffusing capacity for carbon monoxide (DLCO) as defined ...

    Authors: Arturo Cortes-Telles, Esperanza Figueroa-Hurtado, Diana Lizbeth Ortiz-Farias and Gerald Stanley Zavorsky
    Citation: BMC Pulmonary Medicine 2022 22:294
  22. Percutaneous needle biopsy (PNB) and bronchoscopic biopsy (BB) are widely used in the preoperative diagnosis of pulmonary nodules, but whether PNB or BB may cause tumor spread through air spaces (STAS) has not...

    Authors: Yun Ding, Jiuzhen Li, Xin Li, Meilin Xu, Hua Geng and Daqiang Sun
    Citation: BMC Pulmonary Medicine 2022 22:293
  23. Acute exacerbation of chronic obstructive pulmonary disease (COPD) is an important event in the process of disease management. Early identification of high-risk groups for readmission and appropriate measures ...

    Authors: Rui Zhang, Hongyan Lu, Yan Chang, Xiaona Zhang, Jie Zhao and Xindan Li
    Citation: BMC Pulmonary Medicine 2022 22:292
  24. Regulatory T cells (Treg cells) in the peripheral blood of patients with pulmonary tuberculosis (PTB) may be closely related to the progression of PTB. In this study, the distribution characteristics and clini...

    Authors: Xin Yu, Yao Lin, Hui Chen, Min-Juan Wu, Li-Na Huang, Yi-Yan Song, Bin-Bin Gu, Zhi-Jian Ye, Ping Xu, Jian-Ping Zhang and Jun-Chi Xu
    Citation: BMC Pulmonary Medicine 2022 22:291
  25. Fatty acids have diverse immunomodulatory functions and the potential to be associated with inflammatory responses in sarcoidosis.

    Authors: Takahito Suzuki, Masato Karayama, Yusuke Inoue, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui and Takafumi Suda
    Citation: BMC Pulmonary Medicine 2022 22:290
  26. Chronic Obstructive Pulmonary Disease (COPD) is associated with significant mortality and well-defined aetiological factors. Previous reports indicate that mortality from COPD is falling worldwide. This study ...

    Authors: Dominic C. Marshall, Omar Al Omari, Richard Goodall, Joseph Shalhoub, Ian M. Adcock, Kian Fan Chung and Justin D. Salciccioli
    Citation: BMC Pulmonary Medicine 2022 22:289
  27. Tuberculosis (TB) is a chronic infectious disease caused by the Mycobacterium tuberculosis complex (MTBC), which is the leading cause of death from infectious diseases. The rapid and accurate microbiological dete...

    Authors: Meng Fu, Le-Jie Cao, Huai-Ling Xia, Zi-Mei Ji, Na-Na Hu, Zai-Jun Leng, Wang Xie, Yuan Fang, Jun-Qiang Zhang and Da-Qing Xia
    Citation: BMC Pulmonary Medicine 2022 22:288
  28. Relationships between gut microbiomes and airway immunity have been established in murine and human studies of allergy and asthma. Early life Lactobacillus supplementation alters the composition and metabolic pro...

    Authors: Kathryn J. Ray, Clark Santee, Kathryn McCauley, Ariane R. Panzer and Susan V. Lynch
    Citation: BMC Pulmonary Medicine 2022 22:287
  29. C1QTNF6 has been implicated as an essential component in multiple cellular and molecular preliminary event, including inflammation, glucose metabolism, endothelial cell modulation and carcinogenesis. However, ...

    Authors: Guofu Lin, Lanlan Lin, Hai Lin, Yingxuan Xu, Wenhan Chen, Yifei Liu, Jingyang Wu, Shaohua Chen, Qinhui Lin, Yiming Zeng and Yuan Xu
    Citation: BMC Pulmonary Medicine 2022 22:285
  30. Pulmonary tele-rehabilitation can improve adherence to pulmonary rehabilitation. However, there are few reports on home based pulmonary tele-rehabilitation. We assessed the effectiveness of home based pulmonar...

    Authors: Ling Zhang, Ayiguli Maitinuer, Zhichuang Lian, Yafang Li, Wei Ding, Wenyi Wang, Chao Wu and Xiaohong Yang
    Citation: BMC Pulmonary Medicine 2022 22:284
  31. The global prevalence and incidence of nontuberculous mycobacteria (NTM) infection are increasing. However, the prevalence of NTM infection-associated comorbidities remains understudied. Thus, we investigated ...

    Authors: Seung Won Lee, Youngmok Park, Sol Kim, Eun Ki Chung and Young Ae Kang
    Citation: BMC Pulmonary Medicine 2022 22:283
  32. The prognostic value of mixed venous oxygen tension (PvO2) at pulmonary hypertension diagnosis treated with selective pulmonary vasodilators remains unclear. This study sought to investigate the association of Pv...

    Authors: Jun Nagata, Ayumi Sekine, Nobuhiro Tanabe, Yu Taniguchi, Keiichi Ishida, Yuki Shiko, Seiichiro Sakao, Koichiro Tatsumi and Takuji Suzuki
    Citation: BMC Pulmonary Medicine 2022 22:282
  33. Authors: Mario Boehm, Nadine Arnold, Adam Braithwaite, Josephine Pickworth, Changwu Lu, Tatyana Novoyatleva, David G. Kiely, Friedrich Grimminger, Hossein A. Ghofrani, Norbert Weissmann, Werner Seeger, Allan Lawrie, Ralph T. Schermuly and Baktybek Kojonazarov
    Citation: BMC Pulmonary Medicine 2022 22:281

    The original article was published in BMC Pulmonary Medicine 2018 18:41

  34. Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a kind of hypersensitivity drug reaction involving the skin and multiple internal organ systems. Moxifloxacin has rarely been reported ...

    Authors: Yinhong Zhang, Xiaoyan Wang, Yang Cheng, Xiaofang Wang and Yunjian Zhang
    Citation: BMC Pulmonary Medicine 2022 22:279
  35. Chronic obstructive pulmonary disease (COPD) is the third cause of death worldwide. COPD is characterised by dyspnoea, limited exercise tolerance, and muscle dysfunction. Muscle dysfunction has been linked to ...

    Authors: Luis Peñailillo, Denisse Valladares-Ide, Sebastián Jannas-Velas, Marcelo Flores-Opazo, Mauricio Jalón, Laura Mendoza, Ingrid Nuñez and Orlando Diaz-Patiño
    Citation: BMC Pulmonary Medicine 2022 22:278
  36. Long-term home non-invasive ventilation (LTH-NIV) has an impact on the health-related quality of life of patients with chronic hypercapnic respiratory failure (CRF) of different causes. There are generic and s...

    Authors: Marianela Andrade, Mónica Antolini, Krishnna Canales, Cesar Maquilon, Mauricio Fuentes and Marinella Mazzei
    Citation: BMC Pulmonary Medicine 2022 22:277
  37. There has been debate on whether inhaled corticosteroids (ICS) reduce the incidence of lung cancer amongst patients with Chronic Obstructive Lung Disease (COPD). We aimed to perform a systematic review and dos...

    Authors: Tyler Pitre, Michel Kiflen, Terence Ho, Luis M. Seijo, Dena Zeraatkar and Juan P. de Torres
    Citation: BMC Pulmonary Medicine 2022 22:275
  38. The depressive symptom trajectories of COPD individuals and its’ predictors remain to be established. Therefore, this study aimed to explore the trajectories of depressive symptoms and predictors thereof in CO...

    Authors: Cui Wang, Hongbo Chen, Peiyuan Liu, Ziqiu Zou and Shaomei Shang
    Citation: BMC Pulmonary Medicine 2022 22:274
  39. Chronic Obstructive Pulmonary Disease (COPD) remains one of the leading causes of morbidity and mortality worldwide, and its epidemiology in Latin America and the Caribbean is not well described. The aim of th...

    Authors: Juan J. Olortegui-Rodriguez, David R. Soriano-Moreno, Alejandro Benites-Bullón, Pilar P. Pelayo-Luis and Jorge Huaringa-Marcelo
    Citation: BMC Pulmonary Medicine 2022 22:273
  40. Lung adenocarcinoma (LUAD) is currently the leading cause of cancer-related death worldwide. Long noncoding RNAs (lncRNAs) play key roles in tumor occurrence and development as crucial cancer regulators. The p...

    Authors: Yudong Wang, Xingke Mei, Weikang Song, Chen Wang and Xueshan Qiu
    Citation: BMC Pulmonary Medicine 2022 22:272
  41. This paper aims to develop a successful deep learning model with data augmentation technique to discover the clinical uniqueness of chest X-ray imaging features of coal workers' pneumoconiosis (CWP).

    Authors: Hantian Dong, Biaokai Zhu, Xinri Zhang and Xiaomei Kong
    Citation: BMC Pulmonary Medicine 2022 22:271
  42. Despite being minimally invasive, bronchoscopy does not always result in pathological specimens being obtained. Therefore, we investigated whether virtual bronchoscopic navigation (VBN) findings were associate...

    Authors: Atsushi Kitamura, Yutaka Tomishima, Ryosuke Imai, Naoki Nishimura, Kohei Okafuji, Shosei Ro, Torahiko Jinta and Tomohide Tamura
    Citation: BMC Pulmonary Medicine 2022 22:270
  43. The number of patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) is rapidly increasing globally, especially in the older population. However, there is a dearth of evidence regarding the impa...

    Authors: Joong-Yub Kim, Na Young Kim, Hee-Won Jung, Jae-Joon Yim and Nakwon Kwak
    Citation: BMC Pulmonary Medicine 2022 22:269
  44. Large variability in mortality exists in patients of acute respiratory distress syndrome (ARDS), especially those with invasive ventilation. The aim of this study was to develop a model to predict risk of in-h...

    Authors: Weiyan Ye, Rujian Li, Hanwen Liang, Yongbo Huang, Yonghao Xu, Yuchong Li, Limin Ou, Pu Mao, Xiaoqing Liu and Yimin Li
    Citation: BMC Pulmonary Medicine 2022 22:268
  45. Reduced forced vital capacity (FVC) is a risk factor of all-cause mortality; however, the prevalence and determinants of reduced FVC are not available for the Tunisian population. This study investigated the a...

    Authors: Safa Hsan, Nadia Lakhdar, Imed Harrabi, Monia Zaouali, Peter Burney and Meriam Denguezli
    Citation: BMC Pulmonary Medicine 2022 22:267

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