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  1. Asthma, lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are three respiratory diseases characterized by complex mechanisms underlying and genetic predispositions, with asthma having the highe...

    Authors: Anne-Marie Madore, Yohan Bossé, Patricia Margaritte-Jeannin, Emily Vucic, Wan L. Lam, Emmanuelle Bouzigon, Jean Bourbeau and Catherine Laprise
    Citation: BMC Pulmonary Medicine 2022 22:155
  2. Pneumoconiosis is a diffuse interstitial fibronodular lung disease, which is caused by the inhalation of crystalline silica. Whole lung lavage (WLL) is a therapeutic procedure used to treat pneumoconiosis. Thi...

    Authors: Mingyuan Yang, Baoping Li, Bin Wang, Lei Li, Yurong Ji, Yunzhi Zhou, Rui Huang and Qinghao Cheng
    Citation: BMC Pulmonary Medicine 2022 22:152

    The Correction to this article has been published in BMC Pulmonary Medicine 2022 22:201

  3. Smoking is believed as one of the major risk factors resulting in a variety of non-communicable diseases, such as lung cancer and chronic respiratory diseases (CRDs). However, the global burden of CRDs attribu...

    Authors: Hui Gan, Xiangqing Hou, Zheng Zhu, Mingshan Xue, Teng Zhang, Zhifeng Huang, Zhangkai Jason Cheng and Baoqing Sun
    Citation: BMC Pulmonary Medicine 2022 22:149
  4. The economic burden of interstitial lung disease (ILD) is unknown, limiting informed resource allocation and planning. We sought to conduct the first systematic review on the direct, indirect, and overall cost...

    Authors: Alyson W. Wong, John Koo, Christopher J. Ryerson, Mohsen Sadatsafavi and Wenjia Chen
    Citation: BMC Pulmonary Medicine 2022 22:148
  5. Peak inspiratory and expiratory flows (PIF, PEF) are parameters used to evaluate the mechanics of the respiratory system. These parameters can vary based on whether they are measured using mechanical devices v...

    Authors: Laura Gochicoa-Rangel, Keylin Yaoska Rodríguez-Peralta, Ana Karen Gutiérrez-Bautista, Carlos Guzmán-Valderrábano, Rosario Fernández-Plata, Luis Torre-Bouscoulet and David Martínez-Briseño
    Citation: BMC Pulmonary Medicine 2022 22:147
  6. To explore if chest high-resolution computed tomography (HRCT) can make higher accurate stages for thoracic sarcoidosis stage than X-ray (CRX) only.

    Authors: Yuan Zhang, Shan-shan Du, Meng-meng Zhao, Qiu-hong Li, Ying Zhou, Jia-cui Song, Tao Chen, Jing-yun Shi, Bing Jie, Wei Li, Li Shen, Fen Zhang, Yi-liang Su, Yang Hu, Elyse E. Lower, Robert P. Baughman…
    Citation: BMC Pulmonary Medicine 2022 22:146
  7. In this study, we established a chronic obstructive pulmonary disease (COPD) model by stimulating mice with cigarette smoke, and observed the effects of dendritic cells (DCs) overexpressing SOCS1 on Th17, Treg...

    Authors: Shi-xia Liao, Jie Chen, Lan-Ying Zhang, Jing Zhang, Peng-Peng Sun and Yao Ou-Yang
    Citation: BMC Pulmonary Medicine 2022 22:145
  8. Currently, there is no effective tool for predicting the risk of nonventilator hospital-acquired pneumonia (NV-HAP) in older hospitalized patients. The current study aimed to develop and validate a simple nomo...

    Authors: Zhihui Chen, Ziqin Xu, Hongmei Wu, Shengchun Gao, Haihong Wang, Jiaru Jiang, Xiuyang Li and Le Chen
    Citation: BMC Pulmonary Medicine 2022 22:144
  9. The present study was an attempt to investigate cross-cultural adaptability and evaluate the psychometric properties of the Persian version of the Manchester respiratory activities of daily living questionnair...

    Authors: Kumars Eisapareh, Mahin Nazari and Hamidreza Mokarami
    Citation: BMC Pulmonary Medicine 2022 22:143
  10. Dapagliflozin, a selective inhibitor of sodium-glucose cotransporter 2 (SGLT2), can reduce cardiovascular events and mortality in patients with heart failure. A number of mechanisms have been proposed to expla...

    Authors: Yi Tang, Siyuan Tan, Minqi Li, Yijin Tang, Xiaoping Xu, Qinghai Zhang, Qinghua Fu, Mingxiang Tang, Jin He, Yi Zhang, Zhaofen Zheng, Jianqiang Peng, Tengteng Zhu and Wenlin Xie
    Citation: BMC Pulmonary Medicine 2022 22:142
  11. Respiratory involvement is common in immunoglobulin G4-related disease (IgG4-RD). However, severe asthma as the initial clinical manifestation of IgG4-RD is rare and might be neglected by respiratory clinicia...

    Authors: Xiangning Liu, Chi Shao, Chen Yu, Hui Huang, Ruili Pan, Kai Xu, Xin Zhang and Zuojun Xu
    Citation: BMC Pulmonary Medicine 2022 22:141
  12. Pulmonary fibrosis is a fatal lung disease with complex pathogenesis and limited effective therapies. Salt-inducible kinase 2 (SIK2) is a kinase that phosphorylates CRTCs and regulates many physiological proce...

    Authors: Liangneng Zou, Dequn Hong, Kecong Li and Bingyuan Jiang
    Citation: BMC Pulmonary Medicine 2022 22:140
  13. Mesenchymal stem cells (MSCs) have shown therapeutic potential for engraftment to, differentiation into, endothelial cells (ECs). However, low-efficiency yields hinder their use as ECs for therapeutic vascular...

    Authors: Yi Cheng, Wen Gu, Guorui Zhang and Xuejun Guo
    Citation: BMC Pulmonary Medicine 2022 22:139
  14. The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is considered to be associated with chronic inflammation; however, the underlying mechanism remains unclear. Recently, altered gut micr...

    Authors: Yumiko Ikubo, Takayuki Jujo Sanada, Koji Hosomi, Jonguk Park, Akira Naito, Hiroki Shoji, Tomoko Misawa, Rika Suda, Ayumi Sekine, Toshihiko Sugiura, Ayako Shigeta, Hinako Nanri, Seiichiro Sakao, Nobuhiro Tanabe, Kenji Mizuguchi, Jun Kunisawa…
    Citation: BMC Pulmonary Medicine 2022 22:138
  15. Bronchoscopy is critical in the treatment of patients with coronavirus disease (COVID-19), and its use is associated with the challenges of stringent sterilization and virus transmission risk. We developed a d...

    Authors: Zhixin Liang, Guanzhou Zhou, Yi Li, Fei Pan, Jiaqi Zeng, Zhe Luan, Qiang Zhu, Yi Xu, Nana Zhang, Lei Xiang, Yunxiao Jia, Gang Sun and Yunsheng Yang
    Citation: BMC Pulmonary Medicine 2022 22:136
  16. The majority of lung cancer (LC) cases are diagnosed at an advanced stage. Poor awareness of LC symptoms is a contributor to late diagnosis. This study aimed to assess the awareness of LC symptoms among Palest...

    Authors: Mohamedraed Elshami, Hanan Abukmail, Wafa Aqel, Mohammed Alser, Ibrahim Al-Slaibi, Hanan Shurrab, Shahd Qassem, Faten Darwish Usrof, Malik Alruzayqat, Roba Nairoukh, Ahmad Mansour, Rahaf Kittaneh, Nawras Sawafta, Yousef M. N. Habes, Obaida Ghanim, Wesam Almajd Aabed…
    Citation: BMC Pulmonary Medicine 2022 22:135
  17. Cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are often associated with airway fluid acidification. Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene leads t...

    Authors: Kata Csekő, Dóra Hargitai, Lilla Draskóczi, Adrienn Kéri, Pongsiri Jaikumpun, Beáta Kerémi, Zsuzsanna Helyes and Ákos Zsembery
    Citation: BMC Pulmonary Medicine 2022 22:131
  18. Pulmonary infection is common yet serious complication in patients with severe traumatic brain injury (STBI). We aimed to evaluate the predicators of pulmonary infection in STBI patients undergoing tracheostom...

    Authors: Xuelian Zhang, Hui Zhou, Hongying Shen and Mingli Wang
    Citation: BMC Pulmonary Medicine 2022 22:130
  19. The battery-operated hand-held fan (‘fan’) is an inexpensive and portable non-pharmacological intervention for chronic breathlessness. Evidence from randomised controlled trials suggests the fan reduces breath...

    Authors: Tim Luckett, Mary Roberts, Tracy Smith, Maja Garcia, Sarah Dunn, Flavia Swan, Caleb Ferguson, Slavica Kochovska, Jane L. Phillips, Mark Pearson, David C. Currow and Miriam J. Johnson
    Citation: BMC Pulmonary Medicine 2022 22:129
  20. Amiodarone is one of the most commonly used anti-arrhythmic agents. Amiodarone pulmonary toxicity is a potentially fatal adverse effect associated with amiodarone use. Previous studies on the epidemiology and ...

    Authors: Wang Chun Kwok, Ting Fung Ma, Johnny Wai Man Chan, Herbert H. Pang and James Chung Man Ho
    Citation: BMC Pulmonary Medicine 2022 22:128
  21. Silicosis is a chronic occupational pulmonary disease characterized by persistent inflammation and irreversible fibrosis. Considerable evidences now indicate that S100 calcium-binding protein A4 (S100A4) has b...

    Authors: Jing Zhang, Cuifang Yuan, Enhong Li, Yiming Guo, Jie Cui, Heliang Liu, Xiaohui Hao and Lingli Guo
    Citation: BMC Pulmonary Medicine 2022 22:127
  22. To explored the clinical, pathological, and bacteriological characteristics of pleural-based masses occurred during anti-tuberculosis (TB) treatment in patients with pleural TB.

    Authors: Zhengwei Dong, Wei Zhang, Wenwen Sun, Shaojun Zhang, Chenlu Yang, Chunyan Wu and Lin Fan
    Citation: BMC Pulmonary Medicine 2022 22:126
  23. Better insight in patients’ prognosis can help physicians to timely initiate advance care planning (ACP) discussions with patients with chronic obstructive pulmonary disease (COPD). We aimed to identify predic...

    Authors: Catherine Owusuaa, Simone A. Dijkland, Daan Nieboer, Carin C. D. van der Rijt and Agnes van der Heide
    Citation: BMC Pulmonary Medicine 2022 22:125
  24. The etiology of interstitial lung diseases (ILDs) is varied. Early diagnosis and a specific pathological type could significantly improve the prognosis. Mostly, it is difficult to make the etiology diagnosis o...

    Authors: Xianqiu Chen, Jie Luo, Li Yang, Likun Hou, Bing Jie, Yang Hu, Jianxiong Li, Xing Jiang, Jinfu Xu and Kebin Cheng
    Citation: BMC Pulmonary Medicine 2022 22:124

    The Correction to this article has been published in BMC Pulmonary Medicine 2022 22:150

  25. Obstructive sleep apnea (OSA) is a very common and serious health condition which is highly prevalent among U.S. military Veterans. Because the demand for sleep medicine services often overwhelms the availabil...

    Authors: Robert L. Folmer, Eilis A. Boudreau, Charles W. Atwood, Connor J. Smith, Annette M. Totten, Jamie L. Tock, Priyanka Chilakamarri and Kathleen F. Sarmiento
    Citation: BMC Pulmonary Medicine 2022 22:123
  26. Lung clearance index (LCI) is accepted as an early marker of lung disease in cystic fibrosis (CF), however the utility of LCI to identify subgroups of CF disease in the paediatric age group has never been expl...

    Authors: Simone Gambazza, Federico Ambrogi, Federica Carta, Laura Moroni, Maria Russo, Anna Brivio and Carla Colombo
    Citation: BMC Pulmonary Medicine 2022 22:122
  27. The respiratory rate-oxygenation (ROX) index has been increasingly applied to predict the outcome of high-flow nasal cannula (HFNC) in pneumonia patients with acute hypoxemic respiratory failure (AHRF). Howeve...

    Authors: Xiaoyang Zhou, Jiequan Liu, Jianneng Pan, Zhaojun Xu and Jianfei Xu
    Citation: BMC Pulmonary Medicine 2022 22:121
  28. Anti-aminoacyl-tRNA synthetase (anti-ARS) antibodies are myositis-specific autoantibodies that have been identified in a subset of patients with interstitial pneumonia who do not present with dermatomyositis o...

    Authors: Hiroshi Ishimoto, Noriho Sakamoto, Hirokazu Yura, Atsuko Hara, Takashi Kido, Hiroyuki Yamaguchi, Kazuko Yamamoto, Yasushi Obase, Yuji Ishimatsu, Minoru Satoh and Hiroshi Mukae
    Citation: BMC Pulmonary Medicine 2022 22:120
  29. Auscultation with stethoscope has been an essential tool for diagnosing the patients with respiratory disease. Although auscultation is non-invasive, rapid, and inexpensive, it has intrinsic limitations such a...

    Authors: Yoonjoo Kim, YunKyong Hyon, Sunju Lee, Seong-Dae Woo, Taeyoung Ha and Chaeuk Chung
    Citation: BMC Pulmonary Medicine 2022 22:119
  30. To investigate the value of endobronchial ultrasound (EBUS) and virtual bronchoscopic navigation (VBN) combined with rapid on-site evaluation (ROSE) in diagnosing peripheral pulmonary lesions (PPLs).

    Authors: Jia-Chao Qi, Liping Liao, Zhiwei Zhao, HuiXue Zeng, Tiezhu Wang, Miaofen Hu, LiJv Wang, Zhi Wu, Yuming Ye, Yangwu Ou, Zhiming Cai, Qiyin Wu, Qiaozhen Xu, Weiliang Zhang, Wensen Huang, Hao Li…
    Citation: BMC Pulmonary Medicine 2022 22:117
  31. Pulmonary pleomorphic carcinoma (PPC) is a rare tumor, and it usually has an aggressive clinical course and poor prognosis. We aim to analyze the clinicopathological features, management and prognostic factors...

    Authors: Zhongzhong Chen, Jiachang Liu and Lingfeng Min
    Citation: BMC Pulmonary Medicine 2022 22:116
  32. With the growing practice of home mechanical ventilation, there is a need to identify biological markers for adequate follow-up. Red cell distribution width (RDW) is a promising candidate because it is conveni...

    Authors: Luca Valko, Szabolcs Baglyas, Eszter Podmaniczky, Zoltan Prohaszka, Janos Gal and Andras Lorx
    Citation: BMC Pulmonary Medicine 2022 22:115
  33. Lung adenocarcinoma accounts for approximately 40% of all primary lung cancers; however, the mortality rates remain high. Successfully predicting progression and overall (OS) time will provide clinicians with ...

    Authors: Jing Sun, Yan Yan, Yiming Meng, Yushu Ma, Tianzhao Du, Tao Yu and Haozhe Piao
    Citation: BMC Pulmonary Medicine 2022 22:114
  34. Authors: Sergey Udalov, Rio Dumitrascu, Soni Savai Pullamsetti, Hamza M. Al-tamari, Norbert Weissmann, Hossein Ardeschir Ghofrani, Andreas Guenther, Robert Voswinckel, Werner Seeger, Friedrich Grimminger and Ralph T. Schermuly
    Citation: BMC Pulmonary Medicine 2022 22:113

    The original article was published in BMC Pulmonary Medicine 2010 10:26

  35. This study aims to evaluate the diagnostic application and performance of the metagenomic next-generation sequencing (mNGS) in patients suspected of local pulmonary infection by comparing it to the traditional...

    Authors: Shan-shan Su, Xue-bing Chen, Ling-ping Zhou, Peng-cheng Lin, Jun-jie Chen, Cheng-shui Chen, Qing Wu, Jun-ru Ye and Yu-ping Li
    Citation: BMC Pulmonary Medicine 2022 22:112
  36. The zinc transporter ZIP12 is a membrane-spanning protein that transports zinc ions into the cytoplasm from the extracellular space. Recent studies demonstrated that upregulation of ZIP12 is involved in elevat...

    Authors: Chaoyi Ye, Guili Lian, Tingjun Wang, Ai Chen, Weixiao Chen, Jin Gong, Li Luo, Huajun Wang and Liangdi Xie
    Citation: BMC Pulmonary Medicine 2022 22:111
  37. Variability in triazole plasma concentrations by drug interactions is well known. An interaction between voriconazole and flucloxacillin has already been described. In our case we observed a similar interactio...

    Authors: Saartje Verfaillie, Laurent Godinas, Isabel Spriet, Robin Vos and Geert M. Verleden
    Citation: BMC Pulmonary Medicine 2022 22:110
  38. A previous study showed that the lungs are involved in the biogenesis of platelets (PLTs). Thus, the present study aimed to investigate the association between bronchopulmonary dysplasia (BPD), a chronic lung ...

    Authors: Xiaoling Wang, Yan Ma, Shenghui Wang, Wenbin Dong and Xiaoping Lei
    Citation: BMC Pulmonary Medicine 2022 22:109
  39. The clinical treatment of patients suspected of pulmonary infections often rely on empirical antibiotics. However, preliminary diagnoses were based on clinical manifestations and conventional microbiological t...

    Authors: Ping Wei, Yang Gao, Jing Zhang, Jianlong Lin, Huibin Liu, Keqiang Chen, Weikai Lin, Xiaojia Wang, Chune Wang and Chao Liu
    Citation: BMC Pulmonary Medicine 2022 22:108
  40. Neutrophilic inflammation in the airway is a hallmark of bronchiectasis. Neutrophil extracellular traps (NETs) have been reported to play an important role in the occurrence and development of bronchiectasis. ...

    Authors: Shiqi Li, Chunxiao Yu, Hongyu Jie, Xinai Han, Shujing Zou, Quanguang Tan, Shugeng Luo, Youming Chen and Jinhong Wang
    Citation: BMC Pulmonary Medicine 2022 22:107
  41. Chronic Obstructive Pulmonary Disease (COPD) is characterized by progressive and irreversible airflow limitation. Different factors that modify pulmonary function include age, sex, muscular strength, and a his...

    Authors: Nathalie Martínez-Luna, Arturo Orea-Tejeda, Dulce González-Islas, Laura Flores-Cisneros, Candace Keirns-Davis, Rocío Sánchez-Santillán, Ilse Pérez-García, Yael Gastelum-Ayala, Valeria Martínez-Vázquez and Óscar Martínez-Reyna
    Citation: BMC Pulmonary Medicine 2022 22:106
  42. Pulmonary Arterial Hypertension (PAH) is a rare, debilitating, and potentially fatal disease. This study aims to quantify the economic burden of PAH in Spain.

    Authors: Néboa Zozaya, Fernando Abdalla, Ignacio Casado Moreno, Carlos Crespo-Diz, Ana M. Ramírez Gallardo, Joaquín Rueda Soriano, Macarena Alcalá Galán and Álvaro Hidalgo-Vega
    Citation: BMC Pulmonary Medicine 2022 22:105
  43. The study objective was to investigate the use of peripheral blood biomarkers as predictors of patient survival. The aim of this study was to identify the baseline peripheral blood biomarkers associated with c...

    Authors: Jun Wang, Huawei li, Ran Xu, Tong Lu, Jiaying Zhao, Pengfei Zhang, Lidong Qu, Shengqiang Zhang, Jida Guo and Linyou Zhang
    Citation: BMC Pulmonary Medicine 2022 22:104

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