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  1. Reduced forced vital capacity (FVC) is a risk factor of all-cause mortality; however, the prevalence and determinants of reduced FVC are not available for the Tunisian population. This study investigated the a...

    Authors: Safa Hsan, Nadia Lakhdar, Imed Harrabi, Monia Zaouali, Peter Burney and Meriam Denguezli
    Citation: BMC Pulmonary Medicine 2022 22:267
  2. COPD combined with respiratory failure is very common in intensive care unit (ICU). We aimed to evaluate the current status and influencing factors of delirium in elderly COPD patients with undergoing mechanic...

    Authors: Xuecai Fu, Lina Wang, Guihua Wang, Xuefang Liu, Xin Wang, Shuiting Ma and Fengru Miao
    Citation: BMC Pulmonary Medicine 2022 22:266
  3. The diagnostic accuracy of computed tomography (CT)-guided percutaneous core needle biopsy (CNB) for small (≤ 20 mm) ground-glass opacity (GGO) lesions has not been reported in detail.

    Authors: Yang Li, Chao Feng Yang, Jun Peng, Bing Li, Chuan Zhang and Jin Hong Yu
    Citation: BMC Pulmonary Medicine 2022 22:265
  4. The EmPHasis-10 questionnaire is a disease-specific quality of life (QoL) measurement in patients with pulmonary hypertension. We report the results of cross-cultural validation of the Chinese version of the E...

    Authors: Yue Shi, Xingbei Dong, Xiaoyun Hu, Li Weng, Yongtai Liu, Jinzhi Lai, Zhuang Tian, Jiuliang Zhao, Mengtao Li, Jinmin Peng, Qian Wang and Xiaofeng Zeng
    Citation: BMC Pulmonary Medicine 2022 22:264
  5. Aspergillus fumigatus is the most common filamentous fungus isolated from the airways of people with cystic fibrosis (CF). The aim of this study was to investigate how chronic A. fumigatus colonization affects lu...

    Authors: Axel Blomquist, Malin Inghammar, Mahasin Al Shakirchi, Petrea Ericson, Christina Krantz, Marcus Svedberg, Anders Lindblad and Lisa I. Påhlman
    Citation: BMC Pulmonary Medicine 2022 22:263
  6. While asthma comorbidities are associated with higher health care utilisation, lower quality of life and poorer asthma control, the impact of asthma comorbidities on hospitalisation for asthma exacerbation (H-...

    Authors: Wenqiao Wang, Jiangtao Lin, Xin Zhou, Changzheng Wang, Mao Huang, Shaoxi Cai, Ping Chen, Qichang Lin, Jianying Zhou, Yuhai Gu, Yadong Yuan, Dejun Sun, Xiaohong Yang, Lan Yang, Jianmin Huo, Zhuochang Chen…
    Citation: BMC Pulmonary Medicine 2022 22:261
  7. Mesenchymal-epithelial transition exon14 (METex14) skipping is one of the therapeutic driver oncogene mutations in non-small cell lung cancer (NSCLC), and can be treated with tepotinib and capmatinib. There is...

    Authors: Naokazu Watari, Kakuhiro Yamaguchi, Hiroaki Terada, Kosuke Hamai, Ken Masuda, Yoshifumi Nishimura, Shinjiro Sakamoto, Takeshi Masuda, Yasushi Horimasu, Shintaro Miyamoto, Taku Nakashima, Hiroshi Iwamoto, Hiroyasu Shoda, Nobuhisa Ishikawa, Kazunori Fujitaka, Kozue Miyazaki…
    Citation: BMC Pulmonary Medicine 2022 22:260
  8. The expression profiles and molecular mechanisms of CXC chemokine receptors (CXCRs) in Lung adenocarcinoma (LUAD) have been extensively explored. However, the comprehensive prognostic values of CXCR members in...

    Authors: Lian-Tao Hu, Wen-Jun Deng, Zhen-Sheng Chu, Luo Sun, Chun-Bin Zhang, Shi-Zhen Lu, Jin-Ru Weng, Qiao-Sheng Ren, Xin-Yu Dong, Wei-Dong Li, Xue-Bin Li, Yun-Ting Du, Yue Li and Wei-Qun Wang
    Citation: BMC Pulmonary Medicine 2022 22:259
  9. Dupilumab, an anti-IL-4α receptor antibody, is a new treatment for severe or refractory asthma. However, real-world evidence on the efficacy of dupilumab in patients with mild to moderate bronchial asthma is l...

    Authors: Shunsuke Minagawa, Jun Araya, Naoaki Watanabe, Shota Fujimoto, Junko Watanabe, Hiromichi Hara, Takanori Numata, Kazuyoshi Kuwano and Yoshinori Matsuwaki
    Citation: BMC Pulmonary Medicine 2022 22:258
  10. Previous evidence has shown that fractional exhaled nitric oxide (FeNO) and eosinophil count in induced sputum (EO) are cost-effective relative to standard of care in guiding the management of children with pe...

    Authors: Jefferson Antonio Buendía, Diana Guerrero Patiño and Jorge Mario Sánchez Caraballo
    Citation: BMC Pulmonary Medicine 2022 22:257
  11. Chronic cough (CC) is difficult to identify in electronic health records (EHRs) due to the lack of specific diagnostic codes. We developed a natural language processing (NLP) model to identify cough in free-te...

    Authors: Vishal Bali, Jessica Weaver, Vladimir Turzhitsky, Jonathan Schelfhout, Misti L. Paudel, Erin Hulbert, Jesse Peterson-Brandt, Anne-Marie Guerra Currie and Dylan Bakka
    Citation: BMC Pulmonary Medicine 2022 22:256
  12. Data are currently insufficient to support the use of adjuvant chemotherapy (ACT) after surgical resection for stage II or III non-small cell lung cancer (NSCLC) in patients aged ≥ 75 years. In this study we e...

    Authors: Miriam Blasi, Martin E. Eichhorn, Petros Christopoulos, Hauke Winter, Claus Peter Heußel, Felix J. Herth, Rami El Shafie, Katharina Kriegsmann, Mark Kriegsmann, Albrecht Stenzinger, Helge Bischoff, Michael Thomas and Jonas Kuon
    Citation: BMC Pulmonary Medicine 2022 22:255
  13. Asthma is a chronic inflammatory disease of the airways that causes recurring episodes of wheezing, breathlessness, chest tightness and coughing. Inhaled drugs on a daily basis are the cornerstone of asthma tr...

    Authors: Konstantinos P. Exarchos, Nikoletta Rovina, George Krommidas, Dimitrios Latsios, Athena Gogali and Konstantinos Kostikas
    Citation: BMC Pulmonary Medicine 2022 22:254
  14. Early identification of plastic bronchitis (PB) is of great importance and may aid in delivering appropriate treatment. This study aimed to develop and validate a nomogram for predicting PB in patients with re...

    Authors: Lihua Zhao, Tongqiang Zhang, Xiaojian Cui, Linsheng Zhao, Jiafeng Zheng, Jing Ning, Yongsheng Xu and Chunquan Cai
    Citation: BMC Pulmonary Medicine 2022 22:253
  15. Smoking cessation in patients with diagnosed lung cancer has positive effects on cancer therapy and overall prognosis. Despite this, knowledge on smoking cessation in lung cancer patients is sparse.

    Authors: Christian Reinhardt, Markus Harden, Christoph Herrmann-Lingen, Achim Rittmeyer and Stefan Andreas
    Citation: BMC Pulmonary Medicine 2022 22:252
  16. The prognostic value of bronchoalveolar lavage (BAL) fluid analysis in non-human immunodeficiency virus (HIV)-infected patients with Pneumocystis jirovecii pneumonia (PJP) has not been well elucidated. We aimed t...

    Authors: Chiwook Chung, Chae Man Lim, Yeon-Mok Oh, Sang Bum Hong, Chang-Min Choi, Jin Won Huh, Sei Won Lee, Jae Seung Lee, Kyung-Wook Jo, Wonjun Ji, Chan-Jeoung Park, Mina Kim, Heungsup Sung, Young-Uk Cho, Hyo Sin Cho and Ho Cheol Kim
    Citation: BMC Pulmonary Medicine 2022 22:251
  17. This study was performed to develop and validate machine learning models for early detection of ventilator-associated pneumonia (VAP) 24 h before diagnosis, so that VAP patients can receive early intervention ...

    Authors: Yingjian Liang, Chengrui Zhu, Cong Tian, Qizhong Lin, Zhiliang Li, Zhifei Li, Dongshu Ni and Xiaochun Ma
    Citation: BMC Pulmonary Medicine 2022 22:250
  18. End-tidal PCO2 (PetCO2) patterns during exercise testing as well as ventilatory equivalents for CO2 have been reported for different pulmonary vascular diseases but seldomly for the significant differences in exe...

    Authors: Xingxing Sun, Xue Shi, Yuan Cao, Hanqing Zhu, Bigyan Pudasaini, Wenlan Yang, Ping Yuan, Lan Wang, Qinhua Zhao, Sugang Gong, Jinming Liu and Jian Guo
    Citation: BMC Pulmonary Medicine 2022 22:249
  19. Chronic respiratory failure (CRF) can be treated at home with non-invasive ventilation (NIV) and/or long-term oxygen (LTOT). The prevalence of these treatments is largely unknown. We aimed to clarify the preva...

    Authors: Petra Kotanen, Pirkko Brander and Hanna-Riikka Kreivi
    Citation: BMC Pulmonary Medicine 2022 22:248
  20. Acute respiratory distress syndrome (ARDS) has high mortality and is mainly related to the circulatory failure.Therefore, real-time monitoring of cardiac function and structural changes has important clinical ...

    Authors: Daoran Dong, Yan Wang, Chan Wang and Yuan Zong
    Citation: BMC Pulmonary Medicine 2022 22:247
  21. Cyclin-dependent kinase inhibitor 2C (CDKN2C) was identified to participate in the occurrence and development of multiple cancers; however, its roles in small cell lung carcinoma (SCLC) remain unclear.

    Authors: Guo-Sheng Li, Gang Chen, Jun Liu, Deng Tang, Jin-Hua Zheng, Jing Luo, Mei-Hua Jin, Hua-Song Lu, Chong-Xi Bao, Jia Tian, Wu-Sheng Deng, Jing-Wei Fu, Yue Feng, Neng-Yong Zeng, Hua-Fu Zhou and Jin-Liang Kong
    Citation: BMC Pulmonary Medicine 2022 22:246
  22. The survival of patients with lung cancer undergoing critical care has improved. An increasing number of patients with lung cancer have signed a predefined do-not-intubate (DNI) order before admission to the i...

    Authors: Chia-I Shen, Shan-Yao Yang, Hwa-Yen Chiu, Wei-Chih Chen, Wen-Kuang Yu and Kuang-Yao Yang
    Citation: BMC Pulmonary Medicine 2022 22:245
  23. Despite the growing evidence on efficacy, few economic evaluations have evaluated the cost-utility of Pidotimod (PDT) supplementation to decrease the probability of recurrent respiratory tract infections in ch...

    Authors: Jefferson Antonio Buendía, Diana Guerrero Patiño and Erika Fernanda Lindarte
    Citation: BMC Pulmonary Medicine 2022 22:244
  24. The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients ...

    Authors: Salla Kattainen, Anna Lindahl, Tuula Vasankari, Henriikka Ollila, Kirsi Volmonen, Päivi Piirilä, Paula Kauppi, Juuso Paajanen, Hanna-Riikka Kreivi, Linda Ulenius, Tero Varpula, Miia Aro, Jere Reijula and Johanna Hästbacka
    Citation: BMC Pulmonary Medicine 2022 22:243
  25. The prognosis of thymoma with cardiac tamponade is generally poor. Most of the reported thymomas with cardiac tamponade were type B or type AB (mixed thymoma), and cardiac tamponade due to type A thymoma, whic...

    Authors: Mika Takashima, Kozo Kagawa, Toru Sawada, Hiroyuki Hino, Keishi Naruse, Eiji Takeuchi, Shoji Sakiyama and Tsutomu Shinohara
    Citation: BMC Pulmonary Medicine 2022 22:242
  26. Airway clearance techniques are supposed to be a necessary adjunct for the enhancement of impaired peripheral clearance in cystic fibrosis (CF). The objective was to assess the effect of one physiotherapy sess...

    Authors: Plamen Bokov, Michèle Gerardin, Géraldine Brialix, Emmanuelle Da Costa Noble, Romain Juif, Antonia Vital Foucher, Laurence Le Clainche, Véronique Houdouin, Benjamin Mauroy and Christophe Delclaux
    Citation: BMC Pulmonary Medicine 2022 22:241
  27. Silicosis, as an important type of pneumoconiosis, leads to progressive and irreversible conditions from the beginning of inflammation and fibrosis. However, the data on the global burden of silicosis and long...

    Authors: Shimin Chen, Miao Liu and Fei Xie
    Citation: BMC Pulmonary Medicine 2022 22:240
  28. Strong evidence exists for the benefits of pulmonary rehabilitation (PR) for people with chronic obstructive pulmonary disease (COPD), however the availability of culturally safe PR for Aboriginal and Torres S...

    Authors: David P. Meharg, Christine R. Jenkins, Graeme P. Maguire, Stephan Jan, Tim Shaw, Sarah M. Dennis, Zoe McKeough, Vanessa Lee, Kylie G. Gwynne, Debbie McCowen, Boe Rambaldini and Jennifer A. Alison
    Citation: BMC Pulmonary Medicine 2022 22:239
  29. Less is known about the risk factors for acute respiratory distress syndrome (ARDS) in sepsis patients diagnosed according to sepsis 3.0 criteria. Moreover, the risk factors for ARDS severity remain unclear.

    Authors: Yuequan Shi, Liang Wang, Sihan Yu, Xiaochun Ma and Xu Li
    Citation: BMC Pulmonary Medicine 2022 22:238
  30. Around 10% of adults suffer from clinically significant breathlessness. High quality and actionable patient education materials (PEMs) and patient decision aids (PDAs) have an important role for shared decisio...

    Authors: Anthony Paulo Sunjaya, Lexia Bao, Allison Martin, Gian Luca DiTanna and Christine R. Jenkins
    Citation: BMC Pulmonary Medicine 2022 22:237
  31. Even almost 30 years after the ban on the use of asbestos in Germany, the effects of asbestos are still highly relevant in everyday clinical practice in occupational medicine. The aim of this study was to furt...

    Authors: Lennart Ströker, Kersten Peldschus, Robert Herold, Volker Harth and Alexandra Marita Preisser
    Citation: BMC Pulmonary Medicine 2022 22:236
  32. Oscillometry is an emerging technique that offers some advantages over spirometry as it does not require forced exhalation and may detect early changes in respiratory pathology. Obstructive lung disease dispro...

    Authors: Smita Pakhale, Carly Visentin, Saania Tariq, Tina Kaur, Kelly Florence, Ted Bignell, Sadia Jama, Nina Huynh, Robert Boyd, Joanne Haddad and Gonzalo G. Alvarez
    Citation: BMC Pulmonary Medicine 2022 22:235
  33. The application of prone position (PP) in acute respiratory distress syndrome (ARDS) supported by venovenous extracorporeal membrane oxygenation (VV-ECMO) is controversial.

    Authors: Ziying Chen, Min Li, Sichao Gu, Xu Huang, Jingen Xia, Qinghua Ye, Jiangnan Zheng, Qingyuan Zhan and Chen Wang
    Citation: BMC Pulmonary Medicine 2022 22:234
  34. Most threshold limit values are based on animal experiments. Often, the question remains whether these data reflect the situation in humans. As part of a series of investigations in our exposure lab, this stud...

    Authors: Christian Monsé, Götz Westphal, Monika Raulf, Birger Jettkant, Vera van Kampen, Benjamin Kendzia, Leonie Schürmeyer, Christoph Edzard Seifert, Eike-Maximilian Marek, Felicitas Wiegand, Nina Rosenkranz, Christopher Wegener, Rolf Merget, Thomas Brüning and Jürgen Bünger
    Citation: BMC Pulmonary Medicine 2022 22:233
  35. Numerous predictive formulas based on different ethnics have been developed to determine continuous positive airway pressure (CPAP) for patients with obstructive sleep apnea (OSA) without laboratory-based manu...

    Authors: Le Wang, Xing Chen, Dong-hui Wei, Mao-li Liang, Yan Wang, Bao-yuan Chen, Jing Zhang and Jie Cao
    Citation: BMC Pulmonary Medicine 2022 22:232
  36. Lung ischemia–reperfusion injury (LIRI) is a cause of poor prognosis in several lung diseases and after lung transplantation. In LIRI, matrix metalloproteinases and pyroptosis indicators change in parallel, bo...

    Authors: Peng Zhou, Nai-Cheng Song, Zhi-Kun Zheng, Yi-Qing Li and Jin-Song Li
    Citation: BMC Pulmonary Medicine 2022 22:230
  37. Previous studies found that high levels of ventilatory ratio (VR) were associated with a poor prognosis due to worse ventilatory efficiency in acute respiratory distress syndrome patients. However, relatively ...

    Authors: Yingying Yang, Yi Chi, Siyi Yuan, Qing Zhang, Longxiang Su, Yun Long and Huaiwu He
    Citation: BMC Pulmonary Medicine 2022 22:229
  38. Asthma is a chronic inflammatory disease that affects the lungs. Variation in whole blood cell lines is caused by the progression and severity of asthma. Common hematological abnormalities encountered during a...

    Authors: Yenealem Solomon, Berhanu Woldu, Nebiyu Mesfin and Bamlaku Enawgaw
    Citation: BMC Pulmonary Medicine 2022 22:228
  39. This study was designed to explore the early predictive value of the respiratory rate oxygenation (ROX) index modified by PaO2 (mROX) in high-flow nasal cannula (HFNC) therapy in patients with acute hypoxemia res...

    Authors: Zhe Li, Chen Chen, Zhangjun Tan, Yulong Yao, Shunpeng Xing, Yan Li, Yuan Gao, Zhanqi Zhao, Yuxiao Deng and Mingli Zhu
    Citation: BMC Pulmonary Medicine 2022 22:227
  40. Cryobiopsy is an established technique that yields larger and higher-quality samples than does a forceps biopsy. However, it remains underutilised in the diagnosis of peripheral pulmonary lesions (PPLs), mainl...

    Authors: Midori Tanaka, Yuji Matsumoto, Tatsuya Imabayashi, Takuya Kawahara and Takaaki Tsuchida
    Citation: BMC Pulmonary Medicine 2022 22:226
  41. Pulmonary embolism (PE) is a rare complication in bronchiectasis (BE) patients associated with a high rate of mortality and morbidity. However, data regarding bronchiectasis patients complicated with PE are li...

    Authors: Tiantian Deng, Ke Xu, Beishou Wu, Fei Sheng, Xu Li, Zhuxian Zhu and Ziqiang Zhang
    Citation: BMC Pulmonary Medicine 2022 22:225
  42. Post-COVID-19 syndrome is characterized by diverse symptoms and abnormalities that persist beyond 12 weeks from the onset of acute COVID-19. Severity disease has been associated with more musculoskeletal alter...

    Authors: Dulce González-Islas, Carlos Sánchez-Moreno, Arturo Orea-Tejeda, Samantha Hernández-López, Fernanda Salgado-Fernández, Candace Keirns-Davis, Susana Galicia-Amor, Esperanza Trejo-Mellado, Laura Gochicoa-Rangel and Armando Castorena-Maldonado
    Citation: BMC Pulmonary Medicine 2022 22:223
  43. Relapsing polychondritis (RP) patients with tracheal cartilage involvement are different from other patients. The objective of this study was to compare the clinical features and disease patterns between a res...

    Authors: Dong Wang, Lujia Guan, Xin Dong, Xiaofan Zhu and Zhaohui Tong
    Citation: BMC Pulmonary Medicine 2022 22:222
  44. Iatrogenic pneumothorax is common after thoracic procedures. For patients with pneumothorax larger than 15%, simple aspiration is suggested. Although vacuum bottle plus non-tunneled catheter drainage has been ...

    Authors: Shih-Yu Chen, Yao-Wen Kuo, Chao-Chi Ho, Huey-Dong Wu and Hao-Chien Wang
    Citation: BMC Pulmonary Medicine 2022 22:221
  45. Kawasaki disease (KD) is an acute systemic vasculitis that may involve multiple organs. KD shock syndrome (KDSS) is a rare complication of KD. Pulmonary involvement is rare in KD; reports of patients with KD w...

    Authors: Jingwei Liu, Chunfeng Yang, Zhen Zhang and Yumei Li
    Citation: BMC Pulmonary Medicine 2022 22:220
  46. The diagnosis of smear-negative pulmonary tuberculosis (SNPTB) is challenging. Interferon gamma-release assays (IGRAs) may be helpful in early diagnosis among these patients resulting in prompt treatment and f...

    Authors: Tananchai Petnak, Dararat Eksombatchai, Supavit Chesdachai, Ploypin Lertjitbanjong, Pahnwat Taweesedt, Angsupat Pornchai, Charat Thongprayoon, Larry J. Prokop and Zhen Wang
    Citation: BMC Pulmonary Medicine 2022 22:219
  47. Respiratory involvement defines the clinical outcome of neuromuscular diseases (NMD). The lung clearance index (LCI) is a marker of lung ventilation inhomogeneity and indicates small airway disease. It is dete...

    Authors: Mathis Steindor, Anna Pichler, Laura Heitschmidt, Eva Pitsikoulis, Alexandra Kavvalou, Eser Orhan, Margerete Olivier and Florian Stehling
    Citation: BMC Pulmonary Medicine 2022 22:217

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